| Ziegler, Andreas and Kastner, C. (1997): A Minimum Distance Estimation Approach to Estimate the Recombination Fraction from a Marker Locus in Robust Linkage Analysis for Quantitative Traits. Collaborative Research Center 386, Discussion Paper 65 |
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Abstract
Olson and Wijsman (1993) have proposed a robust linkage analysis between quantitative traits and a marker locus using all relative pairs. We extend their work to estimate the recombination fraction using minimum distance estimation after robust linkage analysis requiring a single marker locus. The relevant parameters of the genetic model can also be estimated in the presence of linkage. We illustrate our approach by simulations.
| Item Type: | Paper (Research Paper) |
|---|---|
| Collections: | Mathematics, Computer Science and Statistics > Statistics > Collaborative Research Center 386 Special Research Fields > Special Research Field 386 |
| Subjects: | 500 Science > 510 Mathematics |
| URN: | urn:nbn:de:bvb:19-epub-1459-8 |
| Language: | English |
| ID Code: | 1459 |
| Deposited On: | 04. Apr 2007 |
| Last Modified: | 08. Jan 2013 15:53 |
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