|Ziegler, Andreas and Kastner, C. (1997): A Minimum Distance Estimation Approach to Estimate the Recombination Fraction from a Marker Locus in Robust Linkage Analysis for Quantitative Traits. Collaborative Research Center 386, Discussion Paper 65|
Olson and Wijsman (1993) have proposed a robust linkage analysis between quantitative traits and a marker locus using all relative pairs. We extend their work to estimate the recombination fraction using minimum distance estimation after robust linkage analysis requiring a single marker locus. The relevant parameters of the genetic model can also be estimated in the presence of linkage. We illustrate our approach by simulations.
|Item Type:||Paper (Research Paper)|
|Collections:||Mathematics, Computer Science and Statistics > Statistics > Collaborative Research Center 386|
Special Research Fields > Special Research Field 386
|Subjects:||500 Science > 510 Mathematics|
|Deposited On:||04. Apr 2007|
|Last Modified:||11. Feb 2015 18:08|