| Ziegler, Andreas and Kastner, C. (1997): A Minimum Distance Estimation Approach to Estimate the Recombination Fraction from a Marker Locus in Robust Linkage Analysis for Quantitative Traits. Collaborative Research Center 386, Discussion Paper 65 |
Olson and Wijsman (1993) have proposed a robust linkage analysis between quantitative traits and a marker locus using all relative pairs. We extend their work to estimate the recombination fraction using minimum distance estimation after robust linkage analysis requiring a single marker locus. The relevant parameters of the genetic model can also be estimated in the presence of linkage. We illustrate our approach by simulations.
| Item Type: | Paper (Research Paper) |
|---|---|
| Subjects: | Mathematics, Computer Science and Statistics Mathematics, Computer Science and Statistics > Statistics Mathematics, Computer Science and Statistics > Statistics > Collaborative Research Center 386 |
| Dewey Classification: | 600 Natural sciences and mathematics 600 Natural sciences and mathematics > 510 Mathematics |
| URN: | urn:nbn:de:bvb:19-epub-1459-8 |
| ID Code: | 1459 |
| Deposited On: | 04. Apr 2007 |
| Last Modified: | 28. Jun 2010 14:32 |