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Lech, Maciej; Kantner, Claudia; Kulkarni, Onkar P.; Ryu, Mi; Vlasova, Ekaterina; Heesemann, Jürgen; Anz, David; Endres, Stefan; Kobayashi, Koichi S.; Flavell, Richard A.; Martin, Javier und Anders, Hans-Joachim (Dezember 2011): Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus. In: Annals of the rheumatic diseases, Bd. 70, Nr. 12: S. 2207-17 [PDF, 778kB]

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Abstract

Interleukin-1 receptor-associated kinase (IRAK)-M suppresses Toll-like receptor (TLR)-mediated activation of innate immunity during infection. A similar role was hypothesised for IRAK-M in autoimmunity.

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