|Langhals, Elke and Langhals, Heinz (1990): Alkylation of ketones by use of solid KOH in dimethyl sulfoxide. In: Tetrahedron Letters, Vol. 31, No. 6: pp. 859-862|
A mixture of solid KOH in dimethyl sulfoxide has a strong basicity, but only a low nucleophilicity and is used for methylation of ketones. With this simple and inexpensive reagent complete methylation with yields up to 90% can be achieved.
|Collections:||Chemistry and Pharmacy|
|Subjects:||500 Science > 540 Chemistry|
|Deposited On:||02. May 2008 14:36|
|Last Modified:||08. Jan 2013 16:06|