Synthesis of γ-lactones from alkenes employing p-methoxybenzyl chloride as +CH2---CO−2 equivalent

Bäuml, Englbert and Tscheschlok, Kai and Pock, Rudolf and Mayr, Herbert (1988): Synthesis of γ-lactones from alkenes employing p-methoxybenzyl chloride as +CH2---CO−2 equivalent. In: Tetrahedron Letters, Vol. 29, No. 52: pp. 6925-6926

Abstract

The ZnCl2 catalyzed reaction of p-methoxybenzyl chloride with alkenes yields the 1:1 addition products 3, which are converted into the γ-lactones 4 via Ru(VIII) catalyzed oxidative degradation of the aromatic ring.

• Item Type: Article
• Collections: Chemistry and Pharmacy
• Subjects: 500 Science > 540 Chemistry