Outcome of renal grafts after simultaneous kidney/ pancreas transplantation

Hillebrand, Günther and Illner, Wolf-Dieter and Abendroth, D. and Schneeberger, H. and Petry, I. and Schleibner, S. and Landgraf, R. and Land, Walter (1991): Outcome of renal grafts after simultaneous kidney/ pancreas transplantation. In: Diabetologia, Vol. 34, No. Supple: pp. 16-17

Abstract

Nineteen patients with endstage renal failure due to Type 1 (insulin-dependent) diabetes mellitus received simultaneous pancreas/kidney transplants using bladder drainage technique. Another group of 25 Type 1 diabetic patients received pancreas/kidney transplants by the duct occlusion technique. We observed a higher incidence of rejection episodes in the patients of the bladder drainage group than those in the duct occlusion group, 14 of 19 patients (74%) vs 7 of 25 (28%) respectively. Anti CD3 antibodies (Orthoclone, OKT3) as a part of induction treatment was used more often in the bladder drainage group (58%) than in the control group (20%).

• Item Type: Article
• Keywords: Pancreas/kidney transplantation, Diabetes mellitus, Bladder drainage technique, Renal rejection episode
• Collections: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• Signature: UBM:0760/4 Med.GZ 54(34

References

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Hillebrand O, Castro LA, Landgraf R, Schleibner S, Illner WD, Abendroth D, Land W (1987) Combined/kidney pancreas transplantation — poor long-term outcome of renal grafts. Transpl.Proc. 19:3909–3910

Illner WD, Abendroth D, Landgraf R, Land W (1991) Long-term results in pancreatic transplantation with special emphasis on the use of prolamin. Diabetologia 34 [Suppl 2]

Knechtle SJ, Pirsch JD, Groshek M, et al. (1991) OKT3 vs ALG induction therapy in combined pancreas-kidney transplantation. Transpl.Proc. 23:1581–1582