Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma

Rohrmoser, B. and Lüdecke, D. K. and Scriba, Peter Christian (1985): Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma. In: Journal of Molecular Medicine, Vol. 53, No. 10: pp. 475-477

Abstract

Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a normal X-ray of the sella turcica. Despite these findings, the diagnosis of pituitary was confirmed Cushing's syndrome by computerized tomography and a transphenoidal operation.

• Item Type: Article
• Keywords: Corticotropin-releasing factor (CRF), Cushing's disease, ACTH
• Collections: Medicine
• Subjects: 600 Technology > 610 Medicine and health