Logo
DeutschClear Cookie - decide language by browser settings
Scherthan, Harry and Cremer, Thomas and Arnason, U. and Weier, Heinz-Ulrich and Lima-de-Faria, A. and Fönicke, L. (1994): Comparative chromosome painting discloses homologous Segments in distantly related mammals. In: Nature Genetics, Vol. 6: pp. 342-347
[img]
Preview

PDF

1MB

Abstract

Comparative chromosome painting, termed ZOO-FISH, using DNA libraries from flow sorted human chromosomes 1,16,17 and X, and mouse chromosome 11 discloses the presence of syntenic groups in distantly related mammalian Orders ranging from primates (Homo sapiens), rodents (Mus musculus), even-toed ungulates (Muntiacus muntjak vaginalis and Muntiacus reevesi) and whales (Balaenoptera physalus). These mammalian Orders have evolved separately for 55-80 million years (Myr). We conclude that ZOO-FISH can be used to generate comparative chromosome maps of a large number of mammalian species.