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Anzahl der Publikationen: 29
Zeitschriftenartikel
Bosmans, Laura A.; Tiel, Claudia M. van; Aarts, Suzanne A. B. M.; Willemsen, Lisa; Baardman, Jeroen; Os, Bram W. van; Toom, Myrthe den; Beckers, Linda; Ahern, David J.; Levels, Johannes H. M.; Jongejan, Aldo; Moerland, Perry D.; Verberk, Sanne G. S.; Bossche, Jan van den; Winther, Menno M. P. J. de; Weber, Christian; Atzler, Dorothee; Monaco, Claudia; Gerdes, Norbert; Shami, Annelie und Lutgens, Esther
(2022):
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state.
In: Cardiovascular Research, Bd. 119, Nr. 5: S. 1146-1160
Lacy, Michael; Buerger, Christina; Shami, Annelie; Ahmadsei, Maiwand; Winkels, Holger; Nitz, Katrin; Tiel, Claudia M. van; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Karshovka, Ela; Prange, Koen H. M.; Wu, Yuting; Brouns, Sanne L. N.; Unterlugauer, Sigrid; Kuijpers, Marijke J. E.; Reiche, Myrthe E.; Steffens, Sabine; Edsfeldt, Andreas; Megens, Remco T. A.; Heemskerk, Johan W. M.; Goncalves, Isabel; Weber, Christian; Gerdes, Norbert; Atzler, Dorothee und Lutgens, Esther
(2021):
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease.
In: Nature Communications, Bd. 12, Nr. 1, 3754
Petzold, Tobias; Thienel, Manuela; Dannenberg, Lisa; Mourikis, Philipp; Helten, Carolin; Ayhan, Aysel; M'Pembele, Rene; Achilles, Alina; Trojovky, Kajetan; Konsek, Daniel; Zhang, Zhe; Regenauer, Ron; Pircher, Joachim; Ehrlich, Andreas; Luesebrink, Enzo; Nicolai, Leo; Stocker, Thomas J.; Brandl, Richard; Roeschenthaler, Franz; Strecker, Jan; Saleh, Inas; Spannagl, Michael; Mayr, Christoph H.; Schiller, Herbert B.; Jung, Christian; Gerdes, Norbert; Hoffmann, Till; Levkau, Bodo; Hohlfeld, Thomas; Zeus, Tobias; Schulz, Christian; Kelm, Malte und Polzin, Amin
(2020):
Rivaroxaban Reduces Arterial Thrombosis by Inhibition of FXa-Driven Platelet Activation via Protease Activated Receptor-1.
In: Circulation Research, Bd. 126, Nr. 4: S. 486-500
Shami, Annelie; Atzler, Dorothee; Bosmans, Laura A.; Winkels, Holger; Meiler, Svenja; Lacy, Michael; Tiel, Claudia van; Megens, Remco Ta; Nitz, Katrin; Baardman, Jeroen; Kusters, Pascal; Seijkens, Tom; Buerger, Christina; Janjic, Aleksandar; Riccardi, Carlo; Edsfeldt, Andreas; Monaco, Claudia; Daemen, Mat; Winther, Menno P. J. de; Nilsson, Jan; Weber, Christian; Gerdes, Norbert; Goncalves, Isabel und Lutgens, Esther
(2020):
Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans.
In: European Heart Journal, Bd. 41, Nr. 31: S. 2938-2948
Reiche, Myrthe E.; den Toom, Myrthe; Willemsen, Lisa; van Os, Bram; Gijbels, Marion J. J.; Gerdes, Norbert; Aarts, Suzanne A. B. M. und Lutgens, Esther
(2019):
Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction.
In: BMJ Open Diabetes Research & Care, Bd. 7, Nr. 1, e000829
[PDF, 1MB]
Aarts, Suzanne; Reiche, Myrthe; Toom, Myrthe den; Gijbels, Marion; Beckers, Linda; Gerdes, Norbert und Lutgens, Esther
(2019):
Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH.
In: Scientific Reports, Bd. 9, 14702
[PDF, 4MB]
Seijkens, Tom T. P.; Poels, Kikkie; Meiler, Svenja; van Tiel, Claudia M.; Kusters, Pascal J. H.; Reiche, Myrthe; Atzler, Dorothee; Winkels, Holger; Tjwa, Marc; Poelman, Hessel; Slutter, Bram; Kuiper, Johan; Gijbels, Marion; Kuivenhoven, Jan Albert; Matic, Ljubica Perisic; Paulsson-Berne, Gabrielle; Hedin, Ulf; Hansson, Goran K.; Nicolaes, Gerry A. F.; Daemen, Mat J. A. P.; Weber, Christian; Gerdes, Norbert; de Winther, Menno P. J. und Lutgens, Esther
(2019):
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death.
In: European Heart Journal, Bd. 40, Nr. 4
Bianchini, Mariaelvy; Duchene, Johan; Santovito, Donato; Schloss, Maximilian J.; Evrard, Maximilien; Winkels, Holger; Aslani, Maria; Mohanta, Sarajo K.; Horckmans, Michael; Blanchet, Xavier; Lacy, Michael; Hundelshausen, Philipp von; Atzler, Dorothee; Habenicht, Andreas; Gerdes, Norbert; Pelisek, Jaroslav; Ng, Lai Guan; Steffens, Sabine; Weber, Christian und Megens, Remco T. A.
(2019):
PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function.
In: Science Immunology, Bd. 4, Nr. 36, eaar3054
Pfeiler, Susanne; Winkels, Holger; Kelm, Make und Gerdes, Norbert
(2019):
IL-1 family cytokines in cardiovascular disease.
In: Cytokine, Bd. 122, UNSP 154215
Seijkens, Tom T. P.; Tiel, Claudia M. van; Kusters, Pascal J. H.; Atzler, Dorothee; Soehnlein, Oliver; Zarzycka, Barbara; Aarts, Suzanne A. B. M.; Lameijer, Marnix; Gijbels, Marion J.; Beckers, Linda; Toom, Myrthe den; Slutter, Bram; Kuiper, Johan; Duchene, Johan; Aslani, Maria; Megens, Remco T. A.; Veer, Cornelis van 't; Kooij, Gijs; Schrijver, Roy; Hoeksema, Marten A.; Boon, Louis; Fay, Francois; Tang, Jun; Baxter, Samantha; Jongejan, Aldo; Moerland, Perry D.; Vriend, Gert; Bleijlevens, Boris; Fisher, Edward A.; Duivenvoorden, Raphael; Gerdes, Norbert; Winther, Menno P. J. de; Nicolaes, Gerry A.; Mulder, Willem J. M.; Weber, Christian und Lutgens, Esther
(2018):
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
In: Journal of the American College of Cardiology, Bd. 71, Nr. 5: S. 527-542
Kusters, Pascal J. H.; Seijkens, Tom T. P.; Beckers, Linda; Lievens, Dirk; Winkels, Holger; Waard, Vivian de; Duijvestijn, Adriaan; Liljeqvist, Moritz Lindquist; Roy, Joy; Daugherty, Alan; Newby, Andrew; Gerdes, Norbert und Lutgens, Esther
(2018):
CD40L Deficiency Protects Against Aneurysm Formation.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 5: S. 1076-1085
[PDF, 1MB]
Schmitz, Corinna; Noels, Heidi; El Bounkari, Omar; Straussfeld, Eva; Megens, Remco T. A.; Sternkopf, Marieke; Alampour-Rajabi, Setareh; Krammer, Christine; Tilstam, Pathricia V.; Gerdes, Norbert; Bürger, Christina; Kapurniotu, Aphrodite; Bucala, Richard; Jankowski, Joachim; Weber, Christian und Bernhagen, Jürgen
(2018):
Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis.
In: FASEB Journal, Bd. 32, Nr. 8: S. 4428-4443
Ferrari, Elena; Lutgens, Esther; Weber, Christian und Gerdes, Norbert
(2017):
Atherosclerosis: cell biology and lipoproteins focus on epigenetic modification and macrophage biology.
In: Current Opinion in Lipidology, Bd. 28, Nr. 2: S. 220-221
Seijkens, Tom T.; Winkels, Holger; Gijbels, Marion; Kuivenhoven, Jan A.; Perisic, Ljubica; Paulsson-Berne, Gabrielle; Hedin, Ulf; Hansson, Goran K.; Weber, Christian; Gerdes, Norbert; Winther, Menno P. de und Lutgens, Esther
(2017):
Deficiency of the T Cell Regulator Cbl-B Aggravates Atherosclerosis by Inducing CD8(+) T Cell-Mediated Macrophage Death.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37
Gerdes, Norbert; Bürger, Christina; Winkels, Holger; Weber, Christian und Lutgens, Esther
(2017):
CD40L on T Cells is a Major Contributor to Atherosclerosis in Hyperlipidemic Mice. Abstract 586.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37, Nr. Suppl 1, A586
Ley, Klaus; Gerdes, Norbert und Winkels, Holger
(2017):
ATVB Distinguished Scientist Award How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37, Nr. 5: S. 764-777
[PDF, 612kB]
Shami, Annelie; Meiler, Svenja; Winkels, Holger; Gerdes, Norbert und Lutgens, Esther
(2017):
GITR Activation Promotes Regulatory CD4+T-cell Responses and Stimulates Leukocyte Recruitment in Atherosclerotic Plaques.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37
Willecke, Florian; Gissler, Mark Colin; Michel, Nathaly Anto; Pfeiffer, Katharina; Haertner, Carmen; Hilgendorf, Ingo; Wolf, Dennis; Stachon, Peter; Lutgens, Esther; Holdt, Lesca M.; Bode, Christoph; Gerdes, Norbert und Zirlik, Andreas Zirlik
(2017):
CD40 deficiency in smooth muscle cells ameliorates atherogenesis and promotes a stable plaque phenotype in the aortic root.
In: Atherosclerosis, Bd. 263, E62-E63
Jung, Christian; Lichtenauer, Michael; Strodthoff, Daniela; Winkels, Holger; Wernly, Bernhard; Buerger, Christina; Kamchybekov, Uran; Lutgens, Esther; Figulla, Hans-Reiner und Gerdes, Norbert
(2017):
Alterations in systemic levels of Th1, Th2, and Th17 cytokines in overweight adolescents and obese mice.
In: Pediatric Diabetes, Bd. 18, Nr. 8: S. 714-721
Garg, Garima; Nikolouli, Eirini; Hardtke-Wolenski, Matthias; Toker, Aras; Ohkura, Naganari; Beckstette, Michael; Miyao, Takahisa; Geffers, Robert; Flöss, Stefan; Gerdes, Norbert; Lutgens, Esther; Osterloh, Anke; Hori, Shohei; Sakaguchi, Shimon; Jaeckel, Elmar und Huehn, Jochen
(2017):
Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.
In: Oncotarget, Bd. 8, Nr. 22: S. 35542-35557
Kusters, Pascal; Seijkens, Tom; Bürger, Christina; Legein, Bart; Winkels, Holger; Gijbels, Marion; Barthels, Christian; Bennett, Remy; Beckers, Linda; Atzler, Dorothee; Biessen, Erik; Brocker, Thomas; Weber, Christian; Gerdes, Norbert und Lutgens, Esther
(2017):
Constitutive CD40 Signaling in Dendritic Cells Limits Atherosclerosis by Provoking Inflammatory Bowel Disease and Ensuing Cholesterol Malabsorption.
In: American Journal of Pathology, Bd. 187, Nr. 12: S. 2912-2919
Winkels, Holger; Meiler, Svenja; Smeets, Esther; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Rinne, Petteri; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Bossche, Jan van den; Holdt, Lesca M.; Megens, Remco T. A.; Schmitt, Martin M.; Winther, Menno de; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther und Gerdes, Norbert
(2017):
CD70 limits atherosclerosis and promotes macrophage function.
In: Thrombosis and Haemostasis, Bd. 117, Nr. 1: S. 164-175
Winkels, Holger; Meiler, Svenja; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Hartwig, Helene; Holdt, Lesca M.; Hristov, Michael; Megens, Remco T. A.; Schmitt, Martin M.; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther und Gerdes, Norbert
(2017):
CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice.
In: European Heart Journal, Bd. 38, Nr. 48:
3590-U42
Spitz, Charlotte; Winkels, Holger; Bürger, Christina; Weber, Christian; Lutgens, Esther; Hansson, Göran K. und Gerdes, Norbert
(2016):
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential.
In: Cellular and Molecular Life Sciences, Bd. 73, Nr. 5: S. 901-922
Meiler, Svenja; Lutgens, Esther; Weber, Christian und Gerdes, Norbert
(2016):
Atherosclerosis: cell biology and lipoproteins-focus on interleukin-18 signaling, chemotactic heteromers, and microRNAs.
In: Current Opinion in Lipidology, Bd. 27, Nr. 3: S. 308-309
Meiler, Svenja; Smeets, Esther; Winkels, Holger; Shami, Annelie; Pascutti, Maria Fernanda; Nolte, Martijn A.; Beckers, Linda; Weber, Christian; Gerdes, Norbert und Lutgens, Esther
(2016):
Constitutive GITR Activation Reduces Atherosclerosis by Promoting Regulatory CD4(+) T-Cell ResponsesBrief Report.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 9: S. 1748-1752
Gerdes, Norbert; Seijkens, Tom; Lievens, Dirk; Kuijpers, Marijke J. E.; Winkels, Holger; Projahn, Delia; Hartwig, Helene; Beckers, Linda; Megens, Remco T. A.; Boon, Louis; Noelle, Randolph J.; Soehnlein, Oliver; Heemskerk, Johan W. M.; Weber, Christian und Lutgens, Esther
(2016):
Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 3: S. 482-490
Lichtenauer, Michael; Franz, Marcus; Fritzenwanger, Michael; Figulla, Hans-Reiner; Gerdes, Norbert und Jung, Christian
(2015):
Elevated Plasma Levels of Interleukin-12p40 and Interleukin-16 in Overweight Adolescents.
In: Biomed Research International, 940910
[PDF, 1MB]
Gerdes, Norbert; Winkels, Holger und Weber, Christian
(April 2013):
Atherosclerosis: cell biology and lipoproteins-focus on anti-inflammatory mechanisms as therapeutic options.
In: Current Opinion in Lipidology, Bd. 24, Nr. 2: S. 187-188
[PDF, 146kB]