Publikationen von Haass, Christian

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Anzahl der Publikationen: 109

Zeitschriftenartikel

Ali, Muhammad M.; Sung, Yun Ju; Wang, Fengxian; Fernandez, Maria; Morris, John M.; Fagan, Anne; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella R.; Kleinberger, Gernot J.; Haass, Christian; Ewers, Michael; Levin, Johannes; Farlow, Martin; Perrin, Richard und Cruchaga, Carlos (2022): Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk.
In: PLOS One 17(5), e0267298

Eninger, Timo; Mueller, Stephan A.; Bacioglu, Mehtap; Schweighauser, Manuel; Lambert, Marius; Maia, Luis F.; Neher, Jonas J.; Hornfeck, Sarah M.; Obermueller, Ulrike; Kleinberger, Gernot; Haass, Christian; Kahle, Philipp J.; Staufenbiel, Matthias; Ping, Lingyan; Duong, Duc M.; Levey, Allan I.; Seyfried, Nicholas T.; Lichtenthaler, Stefan F.; Jucker, Mathias und Kaeser, Stephan A. (2022): Signatures of glial activity can be detected in the CSF proteome. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 119, Nr. 24, e2119804119

Rizzo, Giuseppe; Gropper, Julius; Piollet, Marie; Vafadarnejad, Ehsan; Rizakou, Anna; Bandi, Sourish Reddy; Arampatzi, Panagiota; Krammer, Tobias; DiFabion, Nina; Dietrich, Oliver; Arias-Loza, Anahi Paula; Prinz, Marco; Mack, Matthias; Schlepckow, Kai; Haass, Christian; Silvestre, Jean Sebastien; Zernecke, Alma; Saliba, Antoine Emmanuel und Cochain, Clement (2022): Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction. In: Cardiovascular Research, Bd. 119, Nr. 3: S. 772-785

Xia, Dan; Lianoglou, Steve; Sandmann, Thomas; Calvert, Meredith; Suh, Jung H.; Thomsen, Elliot; Dugas, Jason; Pizzo, Michelle E.; DeVos, Sarah L.; Earr, Timothy K.; Lin, Chia-Ching; Davis, Sonnet; Ha, Connie; Leung, Amy Wing-Sze; Hoang, Nguyen; Chau, Roni; Yulyaningsih, Ernie; Lopez, Isabel; Solanoy, Hilda; Masoud, Shababa T.; Liang, Chun-chi; Lin, Karin; Astarita, Giuseppe; Khoury, Nathalie; Zuchero, Joy Yu; Thorne, Robert G.; Shen, Kevin; Miller, Stephanie; Palop, Jorge J.; Garceau, Dylan; Sasner, Michael; Whitesell, Jennifer D.; Harris, Julie A.; Hummel, Selina; Gnorich, Johannes; Wind, Karin; Kunze, Lea; Zatcepin, Artem; Brendel, Matthias; Willem, Michael; Haass, Christian; Barnett, Daniel; Zimmer, Till S.; Orr, Anna G.; Scearce-Levie, Kimberly; Lewcock, Joseph W.; Di Paolo, Gilbert und Sanchez, Pascal E. (2022): Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia. In: Molecular Neurodegeneration, Bd. 17, Nr. 1, 41

Haass, Christian und Selkoe, Dennis (2022): If amyloid drives Alzheimer disease, why have anti-amyloid therapies not yet slowed cognitive decline?
In: PLOS Biology 20(7), e3001694

Paolicelli, Rosa C.; Sierra, Amanda; Stevens, Beth; Tremblay, Marie-Eve; Aguzzi, Adriano; Ajami, Bahareh; Amit, Ido; Audinat, Etienne; Bechmann, Ingo; Bennett, Mariko; Bennett, Frederick; Bessis, Alain; Biber, Knut; Bilbo, Staci; Blurton-Jones, Mathew; Boddeke, Erik; Brites, Dora; Brone, Bert; Brown, Guy C.; Butovsky, Oleg; Carson, Monica J.; Castellano, Bernardo; Colonna, Marco; Cowley, Sally A.; Cunningham, Colm; Davalos, Dimitrios; De Jager, Philip L.; de Strooper, Bart; Denes, Adam; Eggen, Bart J. L.; Eyo, Ukpong; Galea, Elena; Garel, Sonia; Ginhoux, Florent; Glass, Christopher K.; Gokce, Ozgun; Gomez-Nicola, Diego; Gonzalez, Berta; Gordon, Siamon; Graeber, Manuel B.; Greenhalgh, Andrew D.; Gressens, Pierre; Greter, Melanie; Gutmann, David H.; Haass, Christian; Heneka, Michael T.; Heppner, Frank L.; Hong, Soyon; Hume, David A.; Jung, Steffen; Kettenmann, Helmut; Kipnis, Jonathan; Koyama, Ryuta; Lemke, Greg; Lynch, Marina; Majewska, Ania; Malcangio, Marzia; Malm, Tarja; Mancuso, Renzo; Masuda, Takahiro; Matteoli, Michela; McColl, Barry W.; Miron, Veronique E.; Molofsky, Anna Victoria; Monje, Michelle; Mracsko, Eva; Nadjar, Agnes; Neher, Jonas J.; Neniskyte, Urte; Neumann, Harald; Noda, Mami; Peng, Bo; Peri, Francesca; Perry, V. Hugh; Popovich, Phillip G.; Pridans, Clare; Priller, Josef; Prinz, Marco; Ragozzino, Davide; Ransohoff, Richard M.; Salter, Michael W.; Schaefer, Anne; Schafer, Dorothy P.; Schwartz, Michal; Simons, Mikael; Smith, Cody J.; Streit, Wolfgang J.; Tuan, Leng Tay; Tsai, Li-Huei; Verkhratsky, Alexei; Bernhardi, Rommy von; Wake, Hiroaki; Wittamer, Valerie; Wolf, Susanne A.; Wu, Long-Jun und Wyss-Coray, Tony (2022): Microglia states and nomenclature: A field at its crossroads. In: Neuron, Bd. 110, Nr. 21: S. 3458-3483

Morenas-Rodriguez, Estrella; Li, Yan; Nuscher, Brigitte; Franzmeier, Nicolai; Xiong, Chengjie; Suarez-Calvet, Marc; Fagan, Anne M.; Schultz, Stephanie; Gordon, Brian A.; Benzinger, Tammie L. S.; Hassenstab, Jason; McDade, Eric; Feederle, Regina; Karch, Celeste M.; Schlepckow, Kai; Morris, John C.; Kleinberger, Gernot; Nellgard, Bengt; Voglein, Jonathan; Blennow, Kaj; Zetterberg, Henrik; Ewers, Michael; Jucker, Mathias; Levin, Johannes; Bateman, Randall J. und Haass, Christian (2022): Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study. In: Lancet Neurology, Bd. 21, Nr. 4: S. 329-341

Reifschneider, Anika; Robinson, Sophie; Lengerich, Bettina van; Gnörich, Johannes; Logan, Todd; Heindl, Steffanie; Vogt, Miriam A.; Weidinger, Endy; Riedl, Lina; Wind, Karin; Zatcepin, Artem; Pesaemaa, Ida; Haberl, Sophie; Nuscher, Brigitte; Kleinberger, Gernot; Klimmt, Julien; Götzl, Julia K.; Liesz, Arthur; Bürger, Katharina; Brendel, Matthias; Levin, Johannes; Diehl-Schmid, Janine; Suh, Jung; Di Paolo, Gilbert; Lewcock, Joseph W.; Monroe, Kathryn M.; Paquet, Dominik; Capell, Anja und Haass, Christian (2022): Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency. In: EMBO Journal, Bd. 41, Nr. 4, e109108

Riemenschneider, Henrick; Guo, Qiang; Bader, Jakob; Frottin, Frederic; Farny, Daniel; Kleinberger, Gernot; Haass, Christian; Mann, Matthias; Hartl, F. Ulrich; Baumeister, Wolfgang; Hipp, Mark S.; Meissner, Felix; Fernandez-Busnadiego, Ruben und Edbauer, Dieter (2022): Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. In: EMBO Reports, Bd. 23, Nr. 6, e53890

Biechele, Gloria; Monasor, Laura Sebastian; Wind, Karin; Blume, Tanja; Parhizkar, Samira; Arzberger, Thomas; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen; Lichtenthaler, Stefan F.; Haass, Christian; Tahirovic, Sabina und Brendel, Matthias (2022): Glitter in the Darkness? Nonfibrillar beta-Amyloid Plaque Components Significantly Impact the beta-Amyloid PET Signal in Mouse Models of Alzheimer Disease. In: Journal of Nuclear Medicine, Bd. 63, Nr. 1: S. 117-124

Bartos, Laura M.; Kunte, Sebastian T.; Beumers, Philipp; Xiang, Xianyuan; Wind, Karin; Ziegler, Sibylle; Bartenstein, Peter; Choi, Hongyoon; Lee, Dong Soo; Haass, Christian; Baumgarten, Louisa von; Tahirovic, Sabina; Albert, Nathalie L.; Lindner, Simon und Brendel, Matthias (2022): Single-Cell Radiotracer Allocation via Immunomagnetic Sorting to Disentangle PET Signals at Cellular Resolution. In: Journal of Nuclear Medicine, Bd. 63, Nr. 10: S. 1459-1462

Schmitt, Julia; Palleis, Carla; Sauerbeck, Julia; Unterrainer, Marcus; Harris, Stefanie; Prix, Catharina; Weidinger, Endy; Katzdobler, Sabrina; Wagemann, Olivia; Danek, Adrian; Beyer, Leonie; Rauchmann, Boris-Stephan; Rominger, Axel; Simons, Mikael; Bartenstein, Peter; Perneczky, Robert; Haass, Christian; Levin, Johannes; Hoeglinger, Gunter U. und Brendel, Matthias (13. Mai 2021): Dual-Phase β-Amyloid PET Captures Neuronal Injury and Amyloidosis in Corticobasal Syndrome. In: Frontiers in Aging Neuroscience, Bd. 13, 661284 [PDF, 2MB]

Aly, Lilian; Strauss, Eva-Maria; Feucht, Nikolaus; Weiss, Isabella; Berthele, Achim; Mitsdoerffer, Meike; Haass, Christian; Hemmer, Bernhard

; Maier, Mathias; Korn, Thomas und Knier, Benjamin

(2021): Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders. In: Multiple Sclerosis Journal, Bd. 28, Nr. 4, 13524585211028831: S. 522-531 [PDF, 2MB]

Bosch-Queralt, Mar; Cantuti-Castelvetri, Ludovico; Damkou, Alkmini; Schifferer, Martina; Schlepckow, Kai; Alexopoulos, Ioannis; Luetjohann, Dieter; Klose, Christian; Vaculciakova, Lenka; Masuda, Takahiro; Prinz, Marco; Monroe, Kathryn M.; Di Paolo, Gilbert; Lewcock, Joseph W.; Haass, Christian und Simons, Mikael (2021): Diet-dependent regulation of TGF beta impairs reparative innate immune responses after demyelination. In: Nature Metabolism, Bd. 3, Nr. 2: S. 211-227

Colombo, Alessio Vittorio; Sadler, Rebecca Katie; Llovera, Gemma; Singh, Vikramjeet; Roth, Stefan; Heindl, Steffanie; Monasor, Laura Sebastian; Verhoeven, Aswin; Peters, Finn; Parhizkar, Samira; Kamp, Frits; de Aguero, Mercedes Gomez; MacPherson, Andrew J.; Winkler, Edith; Herms, Jochen; Benakis, Corinne; Dichgans, Martin; Steiner, Harald; Giera, Martin; Haass, Christian; Tahirovic, Sabina und Liesz, Arthur (2021): Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition. In: eLife, Bd. 10, e59826 [PDF, 2MB]

Ende, Emma L. van der; Morenas-Rodriguez, Estrella; McMillan, Corey; Grossman, Murray; Irwin, David; Sanchez-Valle, Raquel; Graff, Caroline; Vandenberghe, Rik; Pijnenburg, Yolande A. L.; Laforce, Robert; Le Ber, Isabelle; Lleo, Alberto; Haass, Christian; Suarez-Calvet, Marc; Swieten, John C. van und Seelaar, Harro (2021): CSF sTREM2 is elevated in a subset in GRN-related frontotemporal dementia. In: Neurobiology of Aging, Bd. 103

Franzmeier, Nicolai; Ren, Jinyi; Damm, Alexander; Monte-Rubio, Gemma; Boada, Merce; Ruiz, Agustin; Ramirez, Alfredo; Jessen, Frank; Duezel, Emrah; Rodriguez Gomez, Octavio; Benzinger, Tammie; Goate, Alison; Karch, Celeste M.; Fagan, Anne M.; McDade, Eric; Buerger, Katharina; Levin, Johannes; Duering, Marco; Dichgans, Martin; Suarez-Calvet, Marc; Haass, Christian; Gordon, Brian A.; Lim, Yen Ying; Masters, Colin L.; Janowitz, Daniel; Catak, Cihan; Wolfsgruber, Steffen; Wagner, Michael; Milz, Esther; Moreno-Grau, Sonia; Teipel, Stefan; Grothe, Michel J.; Kilimann, Ingo; Rossor, Martin; Fox, Nick; Laske, Christoph; Chhatwal, Jasmeer; Falkai, Peter; Perneczky, Robert; Lee, Jae-Hong; Spottke, Annika; Boecker, Henning; Brosseron, Frederic; Fliessbach, Klaus; Heneka, Michael T.; Nestor, Peter; Peters, Oliver; Fuentes, Manuel; Menne, Felix; Priller, Josef; Spruth, Eike J.; Franke, Christiana; Schneider, Anja; Westerteicher, Christine; Speck, Oliver; Wiltfang, Jens; Bartels, Claudia; Araque Caballero, Miguel angel; Metzger, Coraline; Bittner, Daniel; Salloway, Stephen; Danek, Adrian; Hassenstab, Jason; Yakushev, Igor; Schofield, Peter R.; Morris, John C.; Bateman, Randall J. und Ewers, Michael (2021): The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. In: Molecular Psychiatry, Bd. 26, Nr. 2: S. 614-628

Joshi, Pranav; Riffel, Florian; Kumar, Sathish; Villacampa, Nadia; Theil, Sandra; Parhizkar, Samira; Haass, Christian; Colonna, Marco; Heneka, Michael T.; Arzberger, Thomas; Herms, Jochen und Walter, Jochen (2021): TREM2 modulates differential deposition of modified and non-modified A beta species in extracellular plaques and intraneuronal deposits. In: Acta Neuropathologica Communications, Bd. 9, Nr. 1, 168

Joshi, Pranav; Riffel, Florian; Satoh, Kanayo; Enomoto, Masahiro; Qamar, Seema; Scheiblich, Hannah; Villacampa, Nadia; Kumar, Sathish; Theil, Sandra; Parhizkar, Samira; Haass, Christian; Heneka, Michael T.; Fraser, Paul E. und Walter, Jochen (2021): Differential interaction with TREM2 modulates microglial uptake of modified A beta species. In: Glia, Bd. 69, Nr. 12: S. 2917-2932

McDade, Eric; Voytyuk, Iryna; Aisen, Paul; Bateman, Randall J.; Carrillo, Maria C.; De Strooper, Bart; Haass, Christian; Reiman, Eric M.; Sperling, Reisa; Tariot, Pierre N.; Yan, Riqiang; Masters, Colin L.; Vassar, Robert und Lichtenthaler, Stefan E. (2021): The case for low-level BACE1 inhibition for the prevention of Alzheimer disease. In: Nature Reviews Neurology, Bd. 17, Nr. 11: S. 703-714

Mori, Kohji; Gotoh, Shiho; Yamashita, Tomoko; Uozumi, Ryota; Kawabe, Yuya; Tagami, Shinji; Kamp, Frits; Nuscher, Brigitte; Edbauer, Dieter; Haass, Christian; Nagai, Yoshitaka und Ikeda, Manabu (2021): The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene. In: Journal of Biological Chemistry, Bd. 297, Nr. 4, 101120

Palleis, Carla; Brendel, Matthias; Finze, Anika; Weidinger, Endy; Boetzel, Kai; Danek, Adrian; Beyer, Leonie; Nitschmann, Alexander; Kern, Maike; Biechele, Gloria; Rauchmann, Boris-Stephan; Haeckert, Jan; Hoellerhage, Matthias; Stephens, Andrew W.; Drzezga, Alexander; Eimeren, Thilo van; Villemagne, Victor L.; Schildan, Andreas; Barthel, Henryk; Patt, Marianne; Sabri, Osama; Bartenstein, Peter; Perneczky, Robert; Haass, Christian; Levin, Johannes und Höglinger, Günter U. (2021): Cortical [F-18]PI-2620 Binding Differentiates Corticobasal Syndrome Subtypes. In: Movement Disorders, Bd. 36, Nr. 9: S. 2104-2115

Vettermann, Franziska J.; Harris, Stefanie; Schmitt, Julia; Unterrainer, Marcus; Lindner, Simon; Rauchmann, Boris-Stephan; Palleis, Carla; Weidinger, Endy; Beyer, Leonie; Eckenweber, Florian; Schuster, Sebastian; Biechele, Gloria; Ferschmann, Christian; Milenkovic, Vladimir M.; Wetzel, Christian H.; Rupprecht, Rainer; Janowitz, Daniel; Buerger, Katharina; Perneczky, Robert; Hoeglinger, Guenter U.; Levin, Johannes; Haass, Christian; Tonn, Joerg C.; Niyazi, Maximilian; Bartenstein, Peter; Albert, Nathalie L. und Brendel, Matthias (2021): Impact of TSPO Receptor Polymorphism on [F-18]GE-180 Binding in Healthy Brain and Pseudo-Reference Regions of Neurooncological and Neurodegenerative Disorders. In: Life-Basel, Bd. 11, Nr. 6, 484

Xiang, Xianyuan; Wind, Karin; Wiedemann, Thomas; Blume, Tanja; Shi, Yuan; Briel, Nils; Beyer, Leonie; Biechele, Gloria; Eckenweber, Florian; Zatcepin, Artem; Lammich, Sven; Ribicic, Sara; Tahirovic, Sabina; Willem, Michael; Deussing, Maximilian; Palleis, Carla; Rauchmann, Boris-Stephan; Gildehaus, Franz-Josef; Lindner, Simon; Spitz, Charlotte; Franzmeier, Nicolai; Baumann, Karlheinz; Rominger, Axel; Bartenstein, Peter; Ziegler, Sibylle; Drzezga, Alexander; Respondek, Gesine; Buerger, Katharina; Perneczky, Robert; Levin, Johannes; Hoeglinger, Guenter U.; Herms, Jochen; Haass, Christian und Brendel, Matthias (2021): Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases. In: Science Translational Medicine, Bd. 13, Nr. 615, eabe5640

Schlepckow, Kai; Monroe, Kathryn M.; Kleinberger, Gernot; Cantuti‐Castelvetri, Ludovico; Parhizkar, Samira; Xia, Dan; Willem, Michael; Werner, Georg; Pettkus, Nadine; Brunner, Bettina; Sülzen, Alice; Nuscher, Brigitte; Hampel, Heike; Xiang, Xianyuan; Feederle, Regina; Tahirovic, Sabina; Park, Joshua I.; Prorok, Rachel; Mahon, Cathal; Liang, Chun‐Chi; Shi, Ju; Kim, Do Jin; Sabelström, Hanna; Huang, Fen; Paolo, Gilbert di; Simons, Mikael; Lewcock, Joseph W. und Haass, Christian

(7. April 2020): Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region. , Bd. 12, Nr. 4, e11227 [PDF, 4MB]

Ewers, Michael; Biechele, Gloria; Suárez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian

und Franzmeier, Nicolai (2020): Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation. In: EMBO, Bd. 12, Nr. 9, e12308 [PDF, 1MB]

Ewers, Michael; Biechele, Gloria; Suarez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian und Franzmeier, Nicolai (2020): Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation. In: EMBO Molecular Medicine, Bd. 12, Nr. 9, e12308

Palleis, Carla; Sauerbeck, Julia; Beyer, Leonie; Harris, Stefanie; Schmitt, Julia; Morenas-Rodriguez, Estrella; Finze, Anika; Nitschmann, Alexander; Ruch-Rubinstein, Francois; Eckenweber, Florian; Biechele, Gloria; Blume, Tanja; Shi, Yuan; Weidinger, Endy; Prix, Catharina; Bötzel, Kai; Danek, Adrian; Rauchmann, Boris-Stephan; Stoecklein, Sophia; Lindner, Simon; Unterrainer, Marcus; Albert, Nathalie L.

; Wetzel, Christian; Rupprecht, Rainer; Rominger, Axel; Bartenstein, Peter; Herms, Jochen; Perneczky, Robert; Haass, Christian; Levin, Johannes; Höglinger, Günter U. und Brendel, Matthias (2020): In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies. In: Movement Disorders, Bd. 36, Nr. 4: S. 883-894

Lüningschöor, Patrick; Wemer, Georg; Stroobants, Stijn; Kakuta, Soichiro; Dombert, Benjamin; Sinske, Daniela; Wanner, Renate; Luellmann-Rauch, Renate; Wefers, Benedikt; Wurst, Wolfgang; D'Hooge, Rudi; Uchiyama, Yasuo; Sendtner, Michael; Haass, Christian; Saftig, Paul; Knöll, Bernd; Capell, Anja und Damme, Markus (2020): The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons. In: Cell Reports, Bd. 30, Nr. 10: S. 3506-3519

Palleis, Carla; Morenas-Rodriguez, Estrella; Martinez Murcia, Francisco Jesus; Giese, Armin; Nuscher, Brigitte; Haass, Christian; Höglinger, Günter; Bötzel, Kai und Levin, Johannes (2020): Longitudinal correlation between neurofilament light chain and UMSARS in Multiple System Atrophy. In: Clinical Neurology and Neurosurgery, Bd. 195, 105924

Berner, Dennis Kristopher; Wessolowski, Luisa; Armbrust, Fred; Schneppenheim, Janna; Schlepckow, Kai; Koudelka, Tomas; Scharfenberg, Franka; Lucius, Ralph; Tholey, Andreas; Kleinberger, Gernot; Haass, Christian; Arnold, Philipp und Becker-Pauly, Christoph (2020): Meprin beta cleaves TREM2 and controls its phagocytic activity on macrophages. In: FASEB Journal, Bd. 34, Nr. 5: S. 6675-6687

Katzmarski, Natalie; Ziegler-Waldkirch, Stephanie; Scheffler, Nina; Witt, Christian; Abou-Ajram, Claudia; Nuscher, Brigitte; Prinz, Marco; Haass, Christian und Meyer-Luehmann, Melanie (2020): A beta oligomers trigger and accelerate A beta seeding. In: Brain Pathology, Bd. 30, Nr. 1: S. 36-45

Takalo, Mari; Wittrahm, Rebekka; Wefers, Benedikt; Parhizkar, Samira; Jokivarsi, Kimmo; Kuulasmaa, Teemu; Makinen, Petra; Martiskainen, Henna; Wurst, Wolfgang; Xiang, Xianyuan; Marttinen, Mikael; Poutiainen, Pekka; Haapasalo, Annakaisa; Hiltunen, Mikko und Haass, Christian (2020): The Alzheimer's disease-associated protective Plc gamma 2-P522R variant promotes immune functions. In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 52

Franzmeier, Nicolai; Suarez-Calvet, M.; Frontzkowski, Lukas; Moore, Annah; Hohman, Timothy J.; Morenas-Rodriguez, Estrella; Nuscher, Brigitte; Shaw, Leslie; Trojanowski, John Q.; Dichgans, Martin; Kleinberger, Gernot; Haass, Christian und Ewers, Michael (2020): Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration. In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 57

Steiner, Andrea; Schlepckow, Kai; Brunner, Bettina; Steiner, Harald; Haass, Christian und Hagn, Franz (2020): gamma-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics. In: EMBO Journal, Bd. 39, Nr. 20, e104247

Werner, Georg; Damme, Markus; Schludi, Martin; Gnoerich, Johannes; Wind, Karin; Fellerer, Katrin; Wefers, Benedikt; Wurst, Wolfgang; Edbauer, Dieter; Brendel, Matthias; Haass, Christian und Capell, Anja (2020): Loss ofTMEM106B potentiates lysosomal andFTLD-like pathology in progranulin-deficient mice. In: EMBO Reports, Bd. 21, Nr. 10, e50241

Sacher, Christian; Blume, Tanja; Beyer, Leonie; Biechele, Gloria; Sauerbeck, Julia; Eckenweber, Florian; Deussing, Maximilian; Focke, Carola; Parhizkar, Samira; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Tahirovic, Sabina; Kleinberger, Gernot; Willem, Michael; Haass, Christian; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen und Brendel, Matthias (2020): Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models. In: Journal of Nuclear Medicine, Bd. 61, Nr. 12

Monasor, Laura Sebastian; Müller, Stephan A.; Colombo, Alessio Vittorio; Tanrioever, Gaye; König, Jasmin; Roth, Stefan; Liesz, Arthur; Berghofer, Anna; Piechotta, Anke; Prestel, Matthias; Saito, Takashi; Saido, Takaomi C.; Herms, Jochen; Willem, Michael; Haass, Christian; Lichtenthaler, Stefan F. und Tahirovic, Sabina (2020): Fibrillar Aβ (beta) triggers microglial proteome alterations and dysfunction in Alzheimer mouse models. In: eLife, Bd. 9, e54083 [PDF, 14MB]

Lewcock, Joseph W.; Schlepckow, Kai; Di Paolo, Gilbert; Tahirovic, Sabina; Monroe, Kathryn M. und Haass, Christian (2020): Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer's Disease. In: Neuron, Bd. 108, Nr. 5: S. 801-821

Abdelhak, Ahmed; Hottenrott, Tilman; Morenas-Rodriguez, Estrella; Suarez-Calvet, Marc; Zettl, Uwe K.; Haass, Christian; Meuth, Sven G.; Rauer, Sebastian; Otto, Markus; Tumani, Hayrettin und Huss, Andre (März 2019): Glial Activation Markers in CSF and Serum From Patients With Primary Progressive Multiple Sclerosis: Potential of Serum GFAP as Disease Severity Marker? In: Frontiers in Neurology, Bd. 10, 280: S. 1-9 [PDF, 1MB]

Götzl, Julia K.; Brendel, Matthias; Werner, Georg; Parhizkar, Samira; Monasor, Laura Sebastian; Kleinberger, Gernot; Colombo, Alessio‐Vittorio; Deussing, Maximilian; Wagner, Matias; Winkelmann, Juliane; Diehl‐Schmid, Janine; Levin, Johannes; Fellerer, Katrin; Reifschneider, Anika; Bultmann, Sebastian; Bartenstein, Peter; Rominger, Axel; Tahirovic, Sabina; Smith, Scott T.; Madore, Charlotte; Butovsky, Oleg; Capell, Anja und Haass, Christian (2019): Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism. In: Embo Molecular Medicine, Bd. 11, Nr. 6 [PDF, 1MB]

Zhou, Qihui; Mareljic, Nikola; Michaelsen, Meike; Parhizkar, Samira; Heindl, Steffanie; Nuscher, Brigitte; Farny, Daniel; Czuppa, Mareike; Schludi, Carina; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Feederle, Regina; Roth, Stefan; Haass, Christian; Arzberger, Thomas; Liesz, Arthur und Edbauer, Dieter (2019): Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. In: EMBO Molecular Medicine, e10919

Voeglein, Jonathan; Willem, Michael; Trambauer, Johannes; Schönecker, Sonja; Dieterich, Marianne; Biskup, Saskia; Giudici, Camilla; Utz, Kathrin; Oberstein, Timo; Brendel, Matthias; Rominger, Axel; Danek, Adrian; Steiner, Harald; Haass, Christian und Levin, Johannes (2019): Identification of a rare presenilin 1 single amino acid deletion mutation (F175del) with unusual amyloid-beta processing effects. In: Neurobiology of Aging, Bd. 84

Nihei, Yoshihiro; Mori, Kohji; Werner, Georg; Arzberger, Thomas; Zhou, Qihui; Khosravi, Barham; Japtok, Julia; Hermann, Andreas; Sommacal, Andreas; Weber, Markus; Kamp, Frits; Nuscher, Brigitte; Edbauer, Dieter und Haass, Christian (2019): Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. In: Acta Neuropathologica, Bd. 139, Nr. 1: S. 99-118

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Deming, Yuetiva; Filipello, Fabia; Cignarella, Francesca; Cantoni, Claudia; Hsu, Simon; Mikesell, Robert; Li, Zeran; Del-Aguila, Jörge L.; Dube, Umber; Farias, Fabiana Geraldo; Bradley, Joseph; Budde, John; Ibanez, Laura; Fernandez, Maria Victoria; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per M.; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Ewers, Michael; Harari, Oscar; Haass, Christian; Brett, Thomas J.; Benitez, Bruno A.; Karch, Celeste M.; Piccio, Laura und Cruchaga, Carlos (2019): The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk. In: Science Translational Medicine, Bd. 11, Nr. 505, eaau2291

Morenas-Rodriguez, Estrella; Alcolea, Daniel; Suarez-Calvet, Marc; Munoz-Llahuna, Laia; Vilaplana, Eduard; Sala, Isabel; Subirana, Andrea; Querol-Vilaseca, Marta; Carmona-Iragui, Maria; Illan-Gala, Ignacio; Ribosa-Nogue, Roser; Blesa, Rafael; Haass, Christian; Fortea, Juan und Lleo, Alberto (2019): Different pattern of CSF glial markers between dementia with Lewy bodies and Alzheimer's disease. In: Scientific Reports, Bd. 9, 7803 [PDF, 2MB]

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Focke, Carola; Blume, Tanja; Zott, Benedikt; Shi, Yuan; Deussing, Maximilian; Peters, Finn; Schmidt, Claudio; Kleinberger, Gernot; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Ozmen, Laurence; Baumann, Karlheinz; Dorostkar, Mario M.; Haass, Christian; Adelsberger, Helmuth; Herms, Jochen; Rominger, Axel und Brendel, Matthias (2019): Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice. In: Journal of Nuclear Medicine, Bd. 60, Nr. 4: S. 548-554

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Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Schlepckow, Kai; Caballero, Miguel Angel Araque; Franzmeier, Nicolai; Capell, Anja; Fellerer, Katrin; Nuscher, Brigitte; Eren, Erden; Levin, Johannes; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian (2019): Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid- pathology. In: Molecular Neurodegeneration, Bd. 14, 1

Falcon, Caries; Monte-Rubio, Gemma C.; Grau-Rivera, Oriol; Suarez-Calvet, Marc; Sanchez-Valle, Raquel; Rami, Lorena; Bosch, Beatriz; Haass, Christian; Domingo Gispert, Juan und Luis Molinuevo, Jose (2019): CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals. In: Neuroimage-Clinical, Bd. 23, UNSP 101801

Zhu, Kaichuan; Xiang, Xianyuan; Filser, Severin; Marinkovic, Petar; Dorostkar, Mario M.; Crux, Sophie; Neumann, Ulf; Shimshek, Derya R.; Rammes, Gerhard; Haass, Christian

; Lichtenthaler, Stefan F.; Gunnersen, Jenny M. und Herms, Jochen (2018): Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6. In: Biological Psychiatry, Bd. 83, Nr. 5: S. 428-437

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; Okamura, Nobuyuki; Herms, Jochen; Yakushev, Igor und Rominger, Axel (2018): Comparison of F-18-T807 and F-18-THK5117 PET in a Mouse Mode of Tau Pathology. In: Frontiers in Aging Neuroscience, Bd. 10, 174 [PDF, 1MB]

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; Suarez-Calvet, Marc; Fagan, Anne M.; Paumier, Katrina; Benzinger, Tammie; Masters, Colin L.; Morris, John C.; Perneczky, Robert; Janowitz, Daniel; Catak, Cihan; Wolfsgruber, Steffen; Wagner, Michael; Teipel, Stefan; Kilimann, Ingo; Ramirez, Alfredo; Rossor, Martin; Jucker, Mathias; Chhatwal, Jasmeer; Spottke, Annika; Böcker, Henning; Brosseron, Frederic; Falkai, Peter

; Fliessbach, Klaus; Heneka, Michael T.; Laske, Christoph; Nestor, Peter; Peters, Oliver; Fuentes, Manuel; Menne, Felix; Priller, Josef; Spruth, Eike J.; Franke, Christiana; Schneider, Anja; Kofler, Barbara; Westerteicher, Christine; Speck, Oliver; Wiltfang, Jens; Bartels, Claudia; Caballero, Miguel Angel Araque; Metzger, Coraline; Bittner, Daniel; Weiner, Michael; Lee, Jae-Hong; Salloway, Stephen; Danek, Adrian; Goate, Alison; Schofield, Peter R.; Bateman, Randall J. und Ewers, Michael (2018): Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease. In: Brain, Bd. 141: S. 1186-1200

Caballero, Miguel Angel Araque; Suarez-Calvet, Marc; Duering, Marco; Franzmeier, Nicolai; Benzinger, Tammie; Fagan, Anne M.; Bateman, Randall J.; Jack, Clifford R.; Levin, Johannes; Dichgans, Martin; Jucker, Mathias; Karch, Celeste; Masters, Colin L.; Morris, John C.; Weiner, Michael; Rossor, Martin; Fox, Nick C.; Lee, Jae-Hong; Salloway, Stephen; Danek, Adrian; Goate, Alison; Yakushev, Igor; Hassenstab, Jason; Schofield, Peter R.; Haass, Christian

und Ewers, Michael (2018): White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease. In: Brain, Bd. 141: S. 3065-3080

Brendel, Matthias; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Probst, Federico; Gildehaus, Franz-Josef; Bartenstein, Peter; Haass, Christian

; Bohrmann, Bernd; Herms, Jochen; Willem, Michael und Rominger, Axel (2018): Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional A beta deposition rate and plaque burden at treatment initiation. In: Theranostics, Bd. 8, Nr. 18: S. 4957-4968 [PDF, 3MB]

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(2018): CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712

Hong, Wei; Wang, Zemin; Liu, Wen; O'Malley, Tiernan T.; Jin, Ming; Willem, Michael; Haass, Christian

; Frosch, Matthew P. und Walsh, Dominic M. (2018): Diffusible, highly bioactive oligomers represent a critical minority of soluble A beta in Alzheimer's disease brain. In: Acta Neuropathologica, Bd. 136, Nr. 1: S. 19-40

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(2018): The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans. In: Molecular Neurodegeneration 13:49 [PDF, 2MB]

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; Castillo-Lizardo, Melissa; Biskup, Saskia; Maetzler, Walter; Rizzu, Patrizia; Heutink, Peter und Synofzik, Matthis (2018): The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects. In: Genetics in Medicine, Bd. 20, Nr. 2: S. 240-249

Götzl, Julia K.; Colombo, Alessio-Vittorio; Fellerer, Katrin; Reifschneider, Anika; Werner, Georg; Tahirovic, Sabina; Haass, Christian

und Capell, Anja (2018): Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice. In: Molecular Neurodegeneration 13:48 [PDF, 4MB]

Brendel, Matthias; Kleinberger, Gernot; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Albert, Nathalie L.; Carlsen, Janette; Lindner, Simon; Gildehaus, Franz Josef; Ozmen, Laurence; Suarez-Calvet, Marc; Bartenstein, Peter; Baumann, Karlheinz; Ewers, Michael; Herms, Jochen; Haass, Christian

und Rominger, Axel (Januar 2017): Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis. In: Frontiers in aging neuroscience, Bd. 9, 8 [PDF, 2MB]

Mazaheri, Fargol; Snaidero, Nicolas; Kleinberger, Gernot; Madore, Charlotte; Daria, Anna; Werner, Georg; Krasemann, Susanne; Capell, Anja; Trümbach, Dietrich; Wurst, Wolfgang; Brunner, Bettina; Bultmann, Sebastian; Tahirovic, Sabina; Kerschensteiner, Martin; Misgeld, Thomas; Butovsky, Oleg und Haass, Christian

(2017): TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury. In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198

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; Lindner, Simon; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Haass, Christian

; Kleinberger, Gernot; Herms, Jochen und Rominger, Axel (2017): Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study. In: Journal of Nuclear Medicine, Bd. 58, Nr. 12: S. 1984-1990

Schlepckow, Kai; Kleinberger, Gernot; Fukumori, Akio; Feederle, Regina; Lichtenthaler, Stefan F.; Steiner, Harald und Haass, Christian

(2017): An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function. In: Embo Molecular Medicine, Bd. 9, Nr. 10: S. 1356-1365 [PDF, 1MB]

Kleinberger, Gernot; Brendel, Matthias; Mracsko, Eva; Wefers, Benedikt; Groeneweg, Linda; Xiang, Xianyuan; Focke, Carola; Deußing, Maximilian; Suarez-Calvet, Marc; Mazaheri, Fargol; Parhizkar, Samira; Pettkus, Nadine; Wurst, Wolfgang; Feederle, Regina; Bartenstein, Peter; Mueggler, Thomas; Arzberger, Thomas; Knuesel, Irene; Rominger, Axel und Haass, Christian

(2017): The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism. In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853

Daria, Anna; Colombo, Alessio; Llovera, Gemma; Hampel, Heike; Willem, Michael; Liesz, Arthur; Haass, Christian

und Tahirovic, Sabina (2017): Young microglia restore amyloid plaque clearance of aged microglia. In: Embo Journal, Bd. 36, Nr. 5: S. 583-603

Scekic-Zahirovic, Jelena; El Oussini, Hajer; Mersmann, Sina; Drenner, Kevin; Wagner, Marina; Sun, Ying; Allmeroth, Kira; Dieterle, Stephane; Sinniger, Jerome; Dirrig-Grosch, Sylvie; Rene, Frederique; Dormann, Dorothee; Haass, Christian

; Ludolph, Albert C.; Lagier-Tourenne, Clotilde; Storkebaum, Erik und Dupuis, Luc (2017): Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis. In: Acta Neuropathologica, Bd. 133, Nr. 6: S. 887-906

Zhou, Qihui; Lehmer, Carina; Michaelsen, Meike; Mori, Kohji; Alterauge, Dominik; Baumjohann, Dirk; Schludi, Martin H.; Greiling, Johanna; Farny, Daniel; Flatley, Andrew; Feederle, Regina; May, Stephanie; Schreiber, Franziska; Arzberger, Thomas; Kuhm, Christoph; Klopstock, Thomas; Hermann, Andreas; Haass, Christian

und Edbauer, Dieter (2017): Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins. In: Embo Molecular Medicine, Bd. 9, Nr. 5: S. 687-702

Davidson, Yvonne S.; Flood, Louis; Robinson, Andrew C.; Nihei, Yoshihiro; Mori, Kohji; Rollinson, Sara; Richardson, Anna; Benson, Bridget C.; Jones, Matthew; Snowden, Julie S.; Pickering-Brown, Stuart; Haass, Christian

; Lashley, Tammaryn und Mann, David M. A. (2017): Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene. In: Acta Neuropathologica Communications 5:31 [PDF, 1MB]

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und Butovsky, Oleg (2017): The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases. In: Immunity, Bd. 47, Nr. 3: S. 566-581

Ohki, Yu; Wenninger-Weinzierl, Andrea; Hruscha, Alexander; Asakawa, Kazuhide; Kawakami, Koichi; Haass, Christian

; Edbauer, Dieter und Schmid, Bettina (2017): Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration. In: Molecular Neurodegeneration 12:6 [PDF, 1MB]

Suarez-Calvet, Marc; Kleinberger, Gernot; Araque Caballero, Miguel Angel; Brendel, Matthias; Rominger, Axel; Alcolea, Daniel; Fortea, Juan; Lleo, Alberto; Blesa, Rafael; Gispert, Juan Domingo; Sanchez-Valle, Raquel; Antonell, Anna; Rami, Lorena; Molinuevo, Jose L.; Brosseron, Frederic; Traschutz, Andreas; Heneka, Michael T.; Struyfs, Hanne; Engelborghs, Sebastiaan; Sleegers, Kristel; Broeckhoven, Christine van; Zetterberg, Henrik; Nellgard, Bengt; Blennow, Kaj; Crispin, Alexander; Ewers, Michael und Haass, Christian

(2016): sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. In: EMBO Molecular Medicine, Bd. 8, Nr. 5: S. 466-476

Xiang, Xianyuan; Werner, Georg; Bohrmann, Bernd; Liesz, Arthur; Mazaheri, Fargol; Capell, Anja; Feederle, Regina; Knuesel, Irene; Kleinberger, Gernot und Haass, Christian

(2016): TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance. In: Embo Molecular Medicine, Bd. 8, Nr. 9: S. 992-1004 [PDF, 1MB]

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; Arzberger, Thomas und Steiner, Harald (2016): Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease. In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465 [PDF, 1MB]

Ben Halima, Saoussen; Mishra, Sabyashachi; Raja, K. Muruga Poopathi; Willem, Michael; Baici, Antonio; Simons, Kai; Bruestle, Oliver; Koch, Philipp; Haass, Christian

; Caflisch, Amedeo und Rajendran, Lawrence (2016): Specific Inhibition of beta-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. In: Cell Reports, Bd. 14, Nr. 9: S. 2127-2141 [PDF, 13MB]

Overhoff, Felix; Brendel, Matthias; Jaworska, Anna; Korzhova, Viktoria; Delker, Andreas; Probst, Federico; Focke, Carola; Gildehaus, Franz-Josef; Carlsen, Janette; Baumann, Karlheinz; Haass, Christian

; Bartenstein, Peter; Herms, Jochen und Rominger, Axel (2016): Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [F-18]-Florbetaben PET Quantitation in Alzheimer's Model Mice. In: Frontiers in Neuroscience, Bd. 10, 45 [PDF, 2MB]

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(2016): Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury. In: Science Translational Medicine, Bd. 8, Nr. 369, 369ra178

Mori, Kohji; Nihei, Yoshihiro; Arzberger, Thomas; Zhou, Qihui; Mackenzie, Ian R.; Hermann, Andreas; Hanisch, Frank; Kamp, Frits; Nuscher, Brigitte; Orozco, Denise; Edbauer, Dieter und Haass, Christian

(2016): Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition. In: Embo Reports, Bd. 17, Nr. 9: S. 1314-1325

Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian

Fleck, Daniel; Voss, Matthias; Brankatschk, Ben; Giudici, Camilla; Hampel, Heike; Schwenk, Benjamin; Edbauer, Dieter; Fukumori, Akio; Steiner, Harald; Kremmer, Elisabeth; Haug-Kröper, Martina; Rossner, Moritz J.; Fluhrer, Regina; Willem, Michael und Haass, Christian

(2016): Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases. In: Journal of Biological Chemistry, Bd. 291, Nr. 1: S. 318-333

Edbauer, Dieter und Haass, Christian

(2016): An amyloid-like cascade hypothesis for C9orf72 ALS/FTD. In: Current Opinion in Neurobiology, Bd. 36: S. 99-106

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und Capell, Anja (2016): Impaired protein degradation in FTLD and related disorders. In: Ageing Research Reviews, Bd. 32: S. 122-139

Gispert, Juan Domingo; Suárez-Calvet, Marc; Monté, Gemma C.; Tucholka, Alan; Falcon, Caries; Rojas, Santiago; Rami, Lorena; Sanchez-Valle, Raquel; Lladó, Albert; Kleinberger, Gemot; Haass, Christian

und Molinuevo, José Luis (2016): Cerebrospinal fluid sTREM2 levels are associated with gray matter volume increases and reduced diffusivity in early Alzheimer's disease. In: Alzheimers & Dementia, Bd. 12, Nr. 12: S. 1259-1272

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(2016): Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin. In: Neurobiology of Aging, Bd. 39, 220.e17

Eichner, Ruth; Heider, Michael; Fernández-Sáiz, Vanesa; Bebber, Frauke van; Garz, Anne-Kathrin; Lemeer, Simone; Rudelius, Martina; Targosz, Bianca-Sabrina; Jacobs, Laura; Knorn, Anna-Maria; Slawska, Jolanta; Platzbecker, Uwe; Germing, Ulrich; Langer, Christian; Knop, Stefan; Einsele, Herrmann; Peschel, Christian; Haass, Christian

; Keller, Ulrich; Schmid, Bettina; Götze, Katharina S.; Kuster, Bernhard und Bassermann, Florian (2016): Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. In: Nature Medicine, Bd. 22, Nr. 7: S. 735-743

Halder, Rashi; Hennion, Magali; Vidal, Ramon O.; Shomroni, Orr; Rahman, Raza-Ur; Rajput, Ashish; Centeno, Tonatiuh Pena; Bebber, Frauke van; Capece, Vincenzo; Vizcaino, Julio C. Garcia; Schuetz, Anna-Lena; Burkhardt, Susanne; Benito, Eva; Sala, Magdalena Navarro; Javan, Sanaz Bahari; Haass, Christian

; Schmid, Bettina; Fischer, Andre und Bonn, Stefan (2016): DNA methylation changes in plasticity genes accompany the formation and maintenance of memory. In: Nature Neuroscience, Bd. 19, Nr. 1: S. 102-110

Haass, Christian

und Neumann, Manuela (2016): Frontotemporal dementias: From molecular mechanisms to therapy PREFACE. In: Journal of Neurochemistry, Bd. 138: S. 3-5

Brendel, Matthias; Jaworska, Anna; Probst, Federico; Overhoff, Felix; Korzhova, Viktoria; Lindner, Simon; Carlsen, Janette; Bartenstein, Peter; Harada, Ryuichi; Kudo, Yukitsuka; Haass, Christian

; Leuven, Fred van; Okamura, Nobuyuki; Herms, Jochen und Rominger, Axel (2016): Small-Animal PET Imaging of Tau Pathology with F-18-THK5117 in 2 Transgenic Mouse Models. In: Journal of Nuclear Medicine, Bd. 57, Nr. 5: S. 792-798

Brendel, Matthias; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Korzhova, Viktoria; Albert, Nathalie L.; Beck, Roswitha; Lindner, Simon; Gildehaus, Franz-Josef; Baumann, Karlheinz; Bartenstein, Peter; Kleinberger, Gernot; Haass, Christian

; Herms, Jochen und Rominger, Axel (2016): Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study. In: Journal of Nuclear Medicine, Bd. 57, Nr. 6: S. 954-960

Suárez-Calvet, Marc; Neumann, Manuela; Arzberger, Thomas; Abou-Ajram, Claudia; Funk, Eva; Hartmann, Hannelore; Edbauer, Dieter; Kremmer, Elisabeth; Göbl, Christoph; Resch, Moritz; Bourgeois, Benjamin; Madl, Tobias; Reber, Stefan; Jutzi, Daniel; Ruepp, Marc-David; Mackenzie, Ian R. A.; Ansorge, Olaf; Dormann, Dorothee und Haass, Christian

(2016): Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS. In: Acta Neuropathologica, Bd. 131, Nr. 4: S. 587-604

Janssens, Jonathan; Philtjens, Stephanie; Kleinberger, Gernot; Mossevelde, Sara van; Zee, Julie van der; Cacace, Rita; Engelborghs, Sebastiaan; Sieben, Anne; Banzhaf-Strathmann, Julia; Dillen, Lubina; Merlin, Celine; Cuijt, Ivy; Robberecht, Caroline; Schmid, Bettina; Santens, Patrick; Ivanoiu, Adrian; Vandenbulcke, Mathieu; Vandenberghe, Rik; Cras, Patrick; De Deyn, Peter P.; Martin, Jean-Jacques; Maudsley, Stuart; Haass, Christian

; Cruts, Marc und Broeckhoven, Christine van (2015): Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains. In: Acta Neuropathologica Communications 3:68 [PDF, 3MB]

Solchenberger, Barbara; Russell, Claire; Kremmer, Elisabeth; Haass, Christian

und Schmid, Bettina (2015): Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology.
In: PLOS ONE 10(3), e0118956 [PDF, 3MB]

Brendel, Matthias; Jaworska, Anna; Grieinger, Eric; Rötzer, Christina; Burgold, Steffen; Gildehaus, Franz-Josef; Carlsen, Janette; Cumming, Paul; Baumann, Karlheinz; Haass, Christian

; Steiner, Harald; Bartenstein, Peter; Herms, Jochen und Rominger, Axel (2015): Cross-Sectional Comparison of Small Animal [F-18]-Florbetaben Amyloid-PET between Transgenic AD Mouse Models.
In: PLOS ONE 10(2), e0116678 [PDF, 1MB]

Kragh, Christine L.; Fillon, Gwenaëlle; Gysbers, Amanda; Hansen, Hanne D.; Neumann, Manuela; Richter-Landsberg, Christiane; Haass, Christian

; Zalc, Bernard; Lubetzki, Catherine; Gai, Wei-Ping; Halliday, Glenda M.; Kahle, Philipp J. und Jensen, Poul H. (2013): FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy.
In: PLOS ONE 8(1), e55243 [PDF, 849kB]

Fluhrer, Regina; Kamp, Frits; Grammer, Gudula; Nuscher, Brigitte; Steiner, Harald; Beyer, Klaus und Haass, Christian

(2011): The Nicastrin ectodomain adopts a highly thermostable structure. In: Biological Chemistry, Bd. 392, Nr. 11: S. 995-1001 [PDF, 1MB]

Fett, Mareike E.; Pilsl, Anna; Paquet, Dominik; Bebber, Frauke van; Haass, Christian

; Tatzelt, Jörg; Schmid, Bettina und Winklhofer, Konstanze F. (30. Juli 2010): Parkin is protective against proteotoxic stress in a transgenic zebrafish model.
In: PLOS ONE 5(7), e11783 [PDF, 3MB]

Paquet, Dominik; Schmid, Bettina und Haass, Christian

(2010): Transgenic Zebrafish as a Novel Animal Model to Study Tauopathies and Other Neurodegenerative Disorders in vivo. In: Neurodegenerative Diseases, Nr. 1-3, S: S. 99-102 [PDF, 100kB]

Fournier, Margot; Vitte, Jérémie; Garrigue, Jérôme; Langui, Dominique; Dullin, Jean-Philippe; Saurini, Françoise; Hanoun, Naïma; Perez-Diaz, Fernando; Cornilleau, Fabien; Joubert, Chantal; Ardila-Osorio, Héctor; Traver, Sabine; Duchateau, René; Goujet-Zalc, Cécile; Paleologou, Katerina; Lashuel, Hilal A.; Haass, Christian

; Duyckaerts, Charles; Cohen-Salmon, Charles; Kahle, Philipp J.; Hamon, Michel; Brice, Alexis und Corti, Olga (2009): Parkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy.
In: PLOS ONE 4(8), e6629 [PDF, 2MB]

Itoh, Naohiro; Okochi, Masayasu; Tagami, Shinji; Nishitomi, Kouhei; Nakayama, Taisuke; Yanagida, Kanta; Fukumori, Akio; Jiang, Jingwei; Mori, Kohji; Hosono, Motoko; Kikuchi, Jyunko; Nakano, Yuko; Takinami, Yoshihiko; Dohi, Keiji; Nishigaki, Atsuko; Takemoto, Hiroshi; Minagawa, Kazuyuki; Katoh, Takaaki; Willem, Michael; Haass, Christian

; Morihara, Takashi; Tanaka, Toshihisa; Kudo, Takashi; Hasegawa, Hiroshi; Nishimura, Masaki; Sakaguchi, Gaku; Kato, Akira und Takeda, Masatoshi (2009): Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor. In: Neurodegenerative Diseases, Nr. 5-6: S. 230-239 [PDF, 556kB]

Fluhrer, Regina und Haass, Christian

(2007): Signal peptide peptidases and gamma-secretase: Cousins of the same protease family? In: Neurodegenerative Diseases, Nr. 2-3: S. 112-116 [PDF, 214kB]

Haass, Christian

und Multhaup, Gerd (2006): Six years of collaborative Alzheimer's disease research in Germany. In: Neurodegenerative Diseases, Nr. 4-5: S. 193-196 [PDF, 904kB]

Kaether, Christoph; Haass, Christian

und Steiner, Harald (2006): Assembly, trafficking and function of gamma-secretase. In: Neurodegenerative Diseases, Nr. 4-5: S. 275-283 [PDF, 402kB]

Haffner, Christof und Haass, Christian

(2006): Cellular functions of gamma-secretase-related proteins. In: Neurodegenerative Diseases, Nr. 4-5: S. 284-289 [PDF, 423kB]

Haffner, Christof und Haass, Christian

(2004): The Biochemical and Genetic Odyssey to the Function of a Nicastrin-Like Protein. In: Neurodegenerative Diseases, Nr. 4-5: S. 192-195 [PDF, 194kB]

Zeitungsartikel

Haass, Christian

und Sewald, Bettina (19. Dezember 2020): Weder Gans noch Rotwein schmecken. In: Münchner Merkur Ausgabe Geretsrieder Merkur, Nr. 294: S. 4

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