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Veröffentlichungsdatum
Anzahl der Publikationen: 44
2023
Hapfelmeier, Alexander 
ORCID: https://orcid.org/0000-0001-6765-6352; On, Begum Irmak; Mühlau, Mark; Kirschke, Jan S.; Berthele, Achim; Gasperi, Christiane; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Wuschek, Alexander; Bussas, Matthias; Boeker, Martin; Bayas, Antonios; Senel, Makbule ORCID: https://orcid.org/0000-0002-2737-7495; Havla, Joachim ORCID: https://orcid.org/0000-0002-4386-1340; Kowarik, Markus C. ORCID: https://orcid.org/0000-0003-1389-5539; Kuhn, Klaus; Gatz, Ingrid; Spengler, Helmut; Wiestler, Benedikt; Grundl, Lioba; Sepp, Dominik und Hemmer, Bernhard
(2023):
Retrospective cohort study to devise a treatment decision score predicting adverse 24-month radiological activity in early multiple sclerosis.
In: Therapeutic Advances in Neurological Disorders, Bd. 16
[PDF, 1MB]
ORCID: https://orcid.org/0000-0001-6765-6352; On, Begum Irmak; Mühlau, Mark; Kirschke, Jan S.; Berthele, Achim; Gasperi, Christiane; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Wuschek, Alexander; Bussas, Matthias; Boeker, Martin; Bayas, Antonios; Senel, Makbule ORCID: https://orcid.org/0000-0002-2737-7495; Havla, Joachim ORCID: https://orcid.org/0000-0002-4386-1340; Kowarik, Markus C. ORCID: https://orcid.org/0000-0003-1389-5539; Kuhn, Klaus; Gatz, Ingrid; Spengler, Helmut; Wiestler, Benedikt; Grundl, Lioba; Sepp, Dominik und Hemmer, Bernhard
(2023):
Retrospective cohort study to devise a treatment decision score predicting adverse 24-month radiological activity in early multiple sclerosis.
In: Therapeutic Advances in Neurological Disorders, Bd. 16
[PDF, 1MB]
2022
Teusen, Clara; Hapfelmeier, Alexander; Schrottenberg, Victoria von; Goekce, Feyza; Pitschel-Walz, Gabriele; Henningsen, Peter; Gensichen, Jochen und Schneider, Antonius
(2022):
Combining the GP's assessment and the PHQ-9 questionnaire leads to more reliable and clinically relevant diagnoses in primary care.
In: PLOS One 17(10), e0276534
In: PLOS One 17(10), e0276534
Nückel, Julius; Planatscher, Elisa; Mohr, Anne Wiebe; Deichl, Karolin; Mijocevic, Hrvoje; Feuerherd, Martin; Wolff, Lisa; Erber, Johanna; Schneider, Jochen; Quante, Michael; Winter, Christoph; Ruland, Jürgen; Hapfelmeier, Alexander; Hammerschmidt, Wolfgang; Moosmann, Andreas; Protzer, Ulrike; Behrends, Uta und Mautner, Josef
(2022):
Association between IgG responses against the nucleocapsid proteins of alphacoronaviruses and COVID-19 severity.
In: Frontiers in Immunology, Bd. 13, 889836
Lahu, Shqipdona; Presch, Antonia; Ndrepepa, Gjin; Menichelli, Maurizio; Valina, Christian; Hemetsberger, Rayyan; Witzenbichler, Bernhard; Bernlochner, Isabell; Joner, Michael; Xhepa, Erion; Hapfelmeier, Alexander; Kufner, Sebastian; Rifatov, Nonglag; Sager, Hendrik B.; Mayer, Katharina; Kessler, Thorsten; Laugwitz, Karl-Ludwig; Richardt, Gert; Schunkert, Heribert; Neumann, Franz-Josef; Sibbing, Dirk; Angiolillo, Dominick J.; Kastrati, Adnan und Cassese, Salvatore
(2022):
Ticagrelor or Prasugrel in Patients With Acute Coronary Syndrome and High Bleeding Risk.
In: Circulation: Cardiovascular Interventions, Bd. 15, Nr. 10, E012204: S. 789-799
Olm, Michaela; Roos, Marco; Hapfelmeier, Alexander; Schneider, Dagmar; Gensichen, Jochen; Berberat, Pascal O. und Schneider, Antonius
(2022):
Bedeutung der Lernumgebung und Reduzierung von Burnout in der stationären Weiterbildung – Analyse des Kompetenzzentrums Weiterbildung Allgemeinmedizin Bayern (KWAB).
In: Zeitschrift für Evidenz Fortbildung und Qualität im Gesundheitswesen, Bd. 168: S. 88-95
Schneider, Antonius; Brunn, Benjamin; Hapfelmeier, Alexander; Schultz, Konrad; Kellerer, Christina und Jörres, Rudolf A.
(2022):
Diagnostic accuracy of FeNO in asthma and predictive value for inhaled corticosteroid responsiveness: A multicentre.
In: Eclinicalmedicine, Bd. 50, 101533
Behnes, Michael; Lahu, Shqipdona; Ndrepepa, Gjin; Menichelli, Maurizio; Mayer, Katharina; Woehrle, Jochen; Bernlochner, Isabell; Gewalt, Senta; Witzenbichler, Bernhard; Hochholzer, Willibald; Sibbing, Dirk; Cassese, Salvatore; Angiolillo, Dominick J.; Hemetsberger, Rayyan; Valina, Christian; Mueller, Arne; Kufner, Sebastian; Hamm, Christian W.; Xhepa, Erion; Hapfelmeier, Alexander; Sager, Hendrik B.; Joner, Michael; Fusaro, Massimiliano; Richardt, Gert; Laugwitz, Karl-Ludwig; Neumann, Franz-Josef; Schunkert, Heribert; Schupke, Stefanie; Kastrati, Adnan und Akin, Ibrahim
(2022):
Ticagrelor or prasugrel in patients with acute coronary syndrome with off-hour versus on-hour presentation: a subgroup analysis of the ISAR-REACT 5 trial.
In: Clinical Research in Cardiology, Bd. 112, Nr. 4: S. 518-528
2021
Buchka, Stefan; Hapfelmeier, Alexander; Gardner, Paul P.; Wilson, Rory und Boulesteix, Anne-Laure
(11. Mai 2021):
On the optimistic performance evaluation of newly introduced bioinformatic methods.
In: Genome Biology, Bd. 22, Nr. 152
[PDF, 526kB]
Kraemer, Bjoern F.; Tesche, Christian; Hapfelmeier, Alexander; Finsterer, Sebastian; Ebersberger, Ullrich; Schluter, Mathis; Ziegler, Martin; Martens, Eimo; Laugwitz, Karl-Ludwig und Schmidt, Martin
(2021):
Radiation Dose Reduction Using a Novel Fluoroscopy System in Patients Undergoing Diagnostic Invasive Coronary Angiography.
In: Journal of Thoracic Imaging, Bd. 36, Nr. 1: S. 52-56
Buchka, Stefan; Hapfelmeier, Alexander; Gardner, Paul P.; Wilson, Rory und Boulesteix, Anne-Laure
(2021):
On the optimistic performance evaluation of newly introduced bioinformatic methods.
In: Genome Biology, Bd. 22, Nr. 1, 152
Coughlan, J. J.; Aytekin, Alp; Lahu, Shqipdona; Ndrepepa, Gjin; Menichelli, Maurizio; Mayer, Katharina; Wohrle, Jochen; Bernlochner, Isabell; Gewalt, Senta; Witzenbichler, Bernhard; Hochholzer, Willibald; Sibbing, Dirk; Cassese, Salvatore; Angiolillo, Dominick J.; Hemetsberger, Rayyan; Valina, Christian; Mueller, Arne; Kufner, Sebastian; Liebetrau, Christoph; Xhepa, Erion; Hapfelmeier, Alexander; Sager, Hendrik B.; Joner, Michael; Fusaro, Massimiliano; Richardt, Gert; Laugwitz, Karl Ludwig; Neumann, Franz Josef; Schunkert, Heribert; Schuepke, Stefanie und Kastrati, Adnan
(2021):
Ticagrelor or Prasugrel for Patients With Acute Coronary Syndrome Treated With Percutaneous Coronary Intervention A Prespecified Subgroup Analysis of a Randomized Clinical Trial.
In: Jama Cardiology, Bd. 6, Nr. 10: S. 1121-1129
Kellerer, Christina; Hapfelmeier, Alexander; Joerres, Rudolf A.; Schultz, Konrad; Brunn, Benjamin und Schneider, Antonius
(2021):
Evaluation of the diagnostic accuracy of fractional exhaled nitric oxide (FeNO) in patients with suspected asthma: study protocol for a prospective diagnostic study.
In: BMJ Open, Bd. 11, Nr. 2, e045420
Kellerer, Christina; Joerres, Rudolf A.; Schneider, Antonius; Alter, Peter; Kauczor, Hans-Ulrich; Jobst, Bertram; Biederer, Jürgen; Bals, Robert; Watz, Henrik; Behr, Jürgen; Kauffmann-Guerrero, Diego; Lutter, Johanna; Hapfelmeier, Alexander; Magnussen, Helgo; Trudzinski, Franziska C.; Welte, Tobias; Vogelmeier, Claus F. und Kahnert, Kathrin
(2021):
Prediction of lung emphysema in COPD by spirometry and clinical symptoms: results from COSYCONET.
In: Respiratory Research, Bd. 22, Nr. 1, 242
Kellerer, Christina; Wagenpfeil, Stefan; Daines, Luke; Joerres, Rudolf A.; Hapfelmeier, Alexander und Schneider, Antonius
(2021):
Diagnostic accuracy of FeNO [fractional exhaled nitric oxide] and asthma symptoms increased when evaluated with a superior reference standard.
In: Journal of Clinical Epidemiology, Bd. 129: S. 86-96
Mayer, Katharina; Hein-Rothweiler, Ralph; Schupke, Stefanie; Janisch, Marion; Bernlochner, Isabell; Ndrepepa, Gjin; Sibbing, Dirk; Gori, Tommaso; Borst, Oliver; Holdenrieder, Stefan; Kupka, Danny; Petzold, Tobias; Bradaric, Christian; Okrojek, Rainer; Leistner, David M.; Trippel, Tobias D.; Muenzel, Thomas; Landmesser, Ulf; Pieske, Burkert; Zeiher, Andreas M.; Gawaz, Meinrad P.; Hapfelmeier, Alexander; Laugwitz, Karl-Ludwig; Schunkert, Heribert; Kastrati, Adnan und Massberg, Steffen
(2021):
Efficacy and Safety of Revacept, a Novel Lesion-Directed Competitive Antagonist to Platelet Glycoprotein VI, in Patients Undergoing Elective Percutaneous Coronary Intervention for Stable Ischemic Heart Disease The Randomized, Double-blind, Placebo-Controlled ISAR-PLASTER Phase 2 Trial.
In: Jama Cardiology, Bd. 6, Nr. 7: S. 753-761
Olm, Michaela; Roos, Marco; Hapfelmeier, Alexander; Schneider, Dagmar; Gensichen, Jochen; Berberat, Pascal O. und Schneider, Antonius
(2021):
Increased professionalization and lower burnout scores were associated with structured residency training program: results of a cross sectional survey.
In: Medical Education Online, Bd. 26, Nr. 1, 1959284
Schneider, Antonius; Buhner, Markus; Herzog, Therese; Laverty, Siona; Ziehfreund, Stefanie; Hapfelmeier, Alexander; Schneider, Dagmar; Berberat, Pascal O. und Roos, Marco
(2021):
Educational Intervention Reduced Family Medicine Residents' Intention to Request Diagnostic Tests: Results of a Controlled Trial.
In: Medical Decision Making, Bd. 41, Nr. 3: S. 329-339
Woehrle, Jochen; Seeger, Julia; Lahu, Shqipdona; Mayer, Katharina; Bernlochner, Isabell; Gewalt, Senta; Menichelli, Maurizio; Witzenbichler, Bernhard; Hochholzer, Willibald; Sibbing, Dirk; Cassese, Salvatore; Angiolillo, Dominick J.; Hemetsberger, Rayyan; Valina, Christian; Kufner, Sebastian; Xhepa, Erion; Hapfelmeier, Alexander; Sager, Hendrik B.; Joner, Michael; Richardt, Gert; Laugwitz, Karl-Ludwig; Neumann, Franz Josef; Schunkert, Heribert; Schuepke, Stefanie; Kastrati, Adnan und Ndrepepa, Gjin
(2021):
Ticagrelor or Prasugrel in Patients With Acute Coronary Syndrome in Relation to Estimated Glomerular Filtration Rate.
In: Jacc-Cardiovascular Interventions, Bd. 14, Nr. 17: S. 1857-1866
2020
Schmidt, Martin; Tesche, Christian; Hapfelmeier, Alexander; Finsterer, Sebastian; Valassis, Gregorius; Ebersberger, Ullrich; Schlueter, Mathis; Ziegler, Martin und Kraemer, Björn F.
(2020):
Significant Radiation Dose Reduction Using a Novel Angiography Platform in Patients Undergoing Cryoballoon Pulmonary Vein Isolation.
In: Journal of Thoracic Imaging, Bd. 35, Nr. 3: S. 167-172
Menichelli, Maurizio; Neumann, Franz-Josef; Ndrepepa, Gjin; Mayer, Katharina; Woehrle, Jochen; Bernlochner, Isabell; Richardt, Gert; Witzenbichler, Bernhard; Sibbing, Dirk; Gewalt, Senta; Angiolillo, Dominick J.; Lahu, Shqipdona; Hamm, Christian W.; Hapfelmeier, Alexander; Trenk, Dietmar; Laugwitz, Karl-Ludwig; Schunkert, Heribert; Schüpke, Stefanie und Kastrati, Adnan
(2020):
Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes Results From a Randomized Trial.
In: Annals of Internal Medicine, Bd. 173, Nr. 6: S. 436-444
Stern, Heiko; Seidenbusch, Michael; Hapfelmeier, Alexander; Meierhofer, Christian; Naumann, Susanne; Schmid, Irene; Spix, Claudia und Ewert, Peter
(2020):
Increased Cancer Incidence Following up to 15 Years after Cardiac Catheterization in Infants under One Year between 1980 and 1998-A Single Center Observational Study.
In: Journal of Clinical Medicine, Bd. 9, Nr. 2, 315
Novotny, Julia; Oberdieck, Paul; Titova, Anna; Pelisek, Jaroslav; Chandraratne, Sue; Nicol, Philipp; Hapfelmeier, Alexander; Joner, Michael; Maegdefessel, Lars; Poppert, Holger; Pircher, Joachim; Massberg, Steffen; Friedrich, Benjamin; Zimmer, Claus; Schulz, Christian und Boeckh-Behrens, Tobias
(2020):
Thrombus NET content is associated with clinical outcome in stroke and myocardial infarction.
In: Neurology, Bd. 94, Nr. 22, E2346-E2360
Aytekin, Alp; Ndrepepa, Gjin; Neumann, Franz-Josef; Menichelli, Maurizio; Mayer, Katharina; Wohrle, Jochen; Bernlochner, Isabell; Lahu, Shqipdona; Richardt, Gert; Witzenbichler, Bernhard; Sibbing, Dirk; Cassese, Salvatore; Angiolillo, Dominick J.; Valina, Christian; Kufner, Sebastian; Liebetrau, Christoph; Hamm, Christian W.; Xhepa, Erion; Hapfelmeier, Alexander; Sager, Hendrik B.; Wustrow, Isabel; Joner, Michael; Trenk, Dietmar; Fusaro, Massimiliano; Laugwitz, Karl-Ludwig; Schunkert, Heribert; Schupke, Stefanie und Kastrati, Adnan
(2020):
Ticagrelor or Prasugrel in Patients With ST-SegmentElevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
In: Circulation, Bd. 142, Nr. 24: S. 2329-2337
Ndrepepa, Gjin; Kastrati, Adnan; Menichelli, Maurizio; Neumann, Franz-Josef; Woehrle, Jochen; Bernlochner, Isabell; Richardt, Gert; Witzenbichler, Bernhard; Sibbing, Dirk; Gewalt, Senta; Angiolillo, Dominick J.; Hamm, Christian W.; Hapfelmeier, Alexander; Trenk, Dietmar; Laugwitz, Karl-Ludwig; Schunkert, Heribert; Schuepke, Stefanie und Mayer, Katharina
(2020):
Ticagrelor or Prasugrel in PatientsWith Acute Coronary Syndromes and Diabetes Mellitus.
In: Jacc-Cardiovascular Interventions, Bd. 13, Nr. 19: S. 2238-2247
Valina, Christian; Neumann, Franz-Josef; Menichelli, Maurizio; Mayer, Katharina; Woehrle, Jochen; Bernlochner, Isabell; Aytekin, Alp; Richardt, Gert; Witzenbichler, Bernhard; Sibbing, Dirk; Cassese, Salvatore; Angiolillo, Dominick J.; Kufner, Sebastian; Liebetrau, Christoph; Hamm, Christian W.; Xhepa, Erion; Hapfelmeier, Alexander; Sager, Hendrik B.; Wustrow, Isabel; Joner, Michael; Trenk, Dietmar; Laugwitz, Karl-Ludwig; Schunkert, Heribert; Schupke, Stefanie und Kastrati, Adnan
(2020):
Ticagrelor or Prasugrel in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.
In: Journal of the American College of Cardiology, Bd. 76, Nr. 21: S. 2436-2446
Haller, Bernhard; Mansmann, Ulrich; Dobler, Dennis; Ulm, Kurt und Hapfelmeier, Alexander
(2020):
Confidence interval estimation for the changepoint of treatment stratification in the presence of a qualitative covariate-treatment interaction.
In: Statistics in Medicine, Bd. 39, Nr. 1: S. 70-96
[PDF, 1MB]
2019
Wuerstle, Silvia; Hapfelmeier, Alexander; Woehrle, Caroline; Dichtl, Karl; Lahmer, Tobias; Rasch, Sebastian; Huber, Wolfgang; Weber, Andreas; Alguel, Hana; Spinner, Christoph; Pichler, Matthias; Schmid, Roland M.; Mayerle, Julia und Schneider, Jochen
(2019):
Changes in pathogen spectrum and antimicrobial resistance development in the time-course of acute necrotizing pancreatitis.
In: Journal of Gastroenterology and Hepatology, Bd. 34, Nr. 12: S. 2096-2103
Jochheim, David; Barbanti, Marco; Capretti, Giuliana; Stefanini, Giulio G.; Hapfelmeier, Alexander; Zadrozny, Magda; Baquet, Moritz; Fischer, Julius; Theiss, Hans; Todaro, Denise; Chieffo, Alaide; Presbitero, Patrizia; Colombo, Antonio; Massberg, Steffen; Tamburino, Corrado und Mehilli, Julinda
(2019):
Oral Anticoagulant Type and Outcomes After Transcatheter Aortic Valve Replacement.
In: Jacc-Cardiovascular Interventions, Bd. 12, Nr. 16: S. 1566-1576
Weber, Lukas M.; Saelens, Wouter; Cannoodt, Robrecht; Soneson, Charlotte; Hapfelmeier, Alexander; Gardner, Paul P.; Boulesteix, Anne-Laure; Saeys, Yvan und Robinson, Mark D.
(2019):
Essential guidelines for computational method benchmarking.
In: Genome Biology
20
[PDF, 868kB]
Boulesteix, Anne-Laure; Janitza, Silke; Hornung, Roman; Probst, Philipp; Busen, Hannah und Hapfelmeier, Alexander
(2019):
Making complex prediction rules applicable for readers: Current practice in random forest literature and recommendations.
In: Biometrical Journal, Bd. 61, Nr. 5: S. 1314-1328
2018
Daltrozzo, Tanja; Hapfelmeier, Alexander; Donnachie, Ewan; Schneider, Antonius und Hemmer, Bernhard
(2018):
A Systematic Assessment of Prevalence, Incidence and Regional Distribution of Multiple Sclerosis in Bavaria From 2006 to 2015.
In: Frontiers in Neurology, Bd. 9, 871
[PDF, 1MB]
2017
Umgelter, Andreas; Hapfelmeier, Alexander; Kopp, Wouter; Rosmalen, Marieke van; Rogiers, Xavier und Guba, Markus
(2017):
Disparities in Eurotransplant Liver Transplantation Wait-List Outcome Between Patients With and Without Model for End-Stage Liver Disease Exceptions.
In: Liver Transplantation, Bd. 23, Nr. 10: S. 1256-1265
Boulesteix, Anne-Laure; Wilson, Rory und Hapfelmeier, Alexander
(2017):
Towards evidence-based computational statistics: Lessons from clinical research on the role and design of real-data benchmark studies.
In: BMC medical research methodology
:17:138
[PDF, 534kB]
2016
Boulesteix, Anne-Laure; Janitza, Silke; Hornung, Roman; Probst, Philipp; Busen, Hannah und Hapfelmeier, Alexander
(19. Dezember 2016):
Making Complex Prediction Rules Applicable for Readers: Current Practice in Random Forest Literature and Recommendations.
Department of Statistics: Technical Reports, Nr. 199
[PDF, 456kB]
Boulesteix, Anne-Laure; Wilson, Rory und Hapfelmeier, Alexander
(27. Oktober 2016):
Towards evidence-based computational statistics: lessons from clinical research on the role and design of real-data benchmark studies.
Department of Statistics: Technical Reports, Nr. 198
[PDF, 270kB]
Strassen, Ulrich; Greve, Jens; Stelter, Klaus; Havel, Miriam; Rotter, Nicole; Veit, Johannes; Schossow, Beate; Hapfelmeier, Alexander; Kehl, Victoria; Kojda, Georg; Hoffmann, Thomas K. und Bas, Murat
(2016):
A Randomized Trial of Icatibant in ACE-Inhibitor-Induced Angioedema.
In: Journal of Allergy and Clinical Immunology, Bd. 137, Nr. 2:
AB243-AB243
Heuser, Fabian; Schulz, Christian M.; Hapfelmeier, Alexander; Lehnen, Nadine; Kochs, Eberhard F. und Wagner, Klaus J.
(2016):
A period of immobility after remifentanil administration protects from nausea: an experimental randomized cross-over study.
In: BMC Anesthesiology
16:90
[PDF, 674kB]
Schneider, Jochen; Hapfelmeier, Alexander; Thöres, Sieglinde; Obermeier, Andreas; Schulz, Christoph; Pförringer, Dominik; Nennstiel, Simon; Spinner, Christoph; Schmid, Roland M.; Algül, Hana; Huber, Wolfgang und Weber, Andreas
(2016):
Mortality Risk for Acute Cholangitis (MAC): a risk prediction model for in-hospital mortality in patients with acute cholangitis.
In: BMC Gastroenterology
16:15
[PDF, 626kB]
2015
Boulesteix, Anne-Laure; Stierle, Veronika und Hapfelmeier, Alexander
(2015):
Publication Bias in Methodological Computational Research.
In: Cancer informatics, Bd. 14: S. 11-19
2014
Hapfelmeier, Alexander; Hothorn, Torsten; Ulm, Kurt und Strobl, Carolin
(2014):
A New Variable Importance Measure for Random Forests with Missing Data.
In: Statistics and Computing, Bd. 24, Nr. 1: S. 21-34
2013
Hapfelmeier, Alexander und Ulm, Kurt
(15. Januar 2013):
Variable selection with Random Forests for missing data.
Department of Statistics: Technical Reports, Nr. 137
[PDF, 563kB]
2012
Hapfelmeier, Alexander; Hothorn, Torsten und Ulm, Kurt
(15. Februar 2012):
Random Forest variable importance with missing data.
Department of Statistics: Technical Reports, Nr. 121
[PDF, 567kB]
Hapfelmeier, Alexander; Hothorn, Torsten und Ulm, Kurt
(2012):
Recursive partitioning on incomplete data using surrogate decisions and multiple imputation.
In: Computational Statistics & Data Analysis, Bd. 56, Nr. 6: S. 1552-1565
2011
Lehmann-Horn, Klaus; Schleich, Eva; Hertzenberg, Deetje; Hapfelmeier, Alexander; Kümpfel, Tania; Bubnoff, Nikolas von; Hohlfeld, Reinhard; Berthele, Achim; Hemmer, Bernhard und Weber, Martin S.
(2011):
Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders.
In: Journal of Neuroinflammation
8:146
[PDF, 490kB]