Publikationen von Hohlfeld, Reinhard

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Anzahl der Publikationen: 70

Zeitschriftenartikel

Ingelfinger, Florian; Gerdes, Lisa Ann; Kavaka, Vladyslav; Krishnarajah, Sinduya; Friebel, Ekaterina; Galli, Edoardo; Zwicky, Pascale; Furrer, Reinhard; Peukert, Christian; Dutertre, Charles-Antoine; Eglseer, Klara Magdalena; Ginhoux, Florent; Flierl-Hecht, Andrea; Kümpfel, Tania; De Feo, Donatella; Schreiner, Bettina; Mundt, Sarah; Kerschensteiner, Martin; Hohlfeld, Reinhard; Beltran, Eduardo und Becher, Burkhard (2022): Twin study reveals non-heritable immune perturbations in multiple sclerosis. In: Nature, Bd. 603, Nr. 7899: S. 152-158

Hohlfeld, Reinhard (2022): Finding cures for neurological diseases: 'The Brain Under Siege: Solving the Mystery of Brain Disease, and How Scientists are Following the Clues to a Cure'. In: Brain, Bd. 145, Nr. 11, awac282: S. 4138-4140

Schneider-Hohendorf, Tilman; Gerdes, Lisa Ann; Pignolet, Beatrice; Gittelman, Rachel; Ostkamp, Patrick; Rubelt, Florian; Raposo, Catarina; Tackenberg, Bjoern; Riepenhausen, Marianne; Janoschka, Claudia; Wuensch, Christian; Bucciarelli, Florence; Flierl-Hecht, Andrea; Beltran, Eduardo; Kuempfel, Tania; Anslinger, Katja; Gross, Catharina C.; Chapman, Heidi; Kaplan, Ian; Brassat, David; Wekerle, Hartmut; Kerschensteiner, Martin; Klotz, Luisa; Luenemann, Jan D.; Hohlfeld, Reinhard; Liblau, Roland; Wiendl, Heinz und Schwab, Nicholas (2022): Broader Epstein-Barr virus-specific T cell receptor repertoire in patients with multiple sclerosis. In: Journal of Experimental Medicine, Bd. 219, Nr. 11, e20220650

Correale, Jorge; Hohlfeld, Reinhard und Baranzini, Sergio E. (2022): The role of the gut microbiota in multiple sclerosis. In: Nature Reviews Neurology, Bd. 18, Nr. 9: S. 544-558

Havla, Joachim; Schultz, Yannick; Zimmermann, Hanna; Hohlfeld, Reinhard; Danek, Adrian

und Kümpfel, Tania (2022): First manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine. In: Journal of neurology, Bd. 269, Nr. 1: S. 55-58 [PDF, 746kB]

Havla, Joachim

und Hohlfeld, Reinhard (2022): Antibody Therapies for Progressive Multiple Sclerosis and for Promoting Repair. In: Neurotherapeutics, Bd. 19, Nr. 3: S. 774-784 [PDF, 586kB]

Ostkamp, Patrick; Salmen, Anke; Pignolet, Beatrice; Görlich, Dennis; Andlauer, Till F. M.; Schulte-Mecklenbeck, Andreas; Gonzalez-Escamilla, Gabriel; Bucciarelli, Florence; Gennero, Isabelle; Breuer, Johanna; Antony, Gisela; Schneider-Hohendorf, Tilman; Mykicki, Nadine; Bayas, Antonios; Bergh, Florian Then; Bittner, Stefan; Hartung, Hans-Peter; Friese, Manuel A.; Linker, Ralf A.; Luessi, Felix; Lehmann-Horn, Klaus; Mühlau, Mark; Paul, Friedemann; Stangel, Martin; Tackenberg, Björn; Tumani, Hayrettin; Warnke, Clemens; Weber, Frank; Wildemann, Brigitte; Zettl, Uwe K.; Ziemann, Ulf; Müller-Myhsok, Bertram; Kümpfel, Tania; Klotz, Luisa; Meuth, Sven G.; Zipp, Frauke; Hemmer, Bernhard; Hohlfeld, Reinhard; Brassat, David; Gold, Ralf; Gross, Catharina C.; Lukas, Carsten; Groppa, Sergiu; Loser, Karin; Wiendl, Heinz und Schwab, Nicholas (2021): Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 1, e2018457118

Mortazavi, Matin; Hizarci, Oeznur; Gerdes, Lisa Ann; Havla, Joachim; Kuempfel, Tania; Hohlfeld, Reinhard; Stoecklein, Sophia; Keeser, Daniel und Ertl-Wagner, Birgit (2021): Multiple sclerosis and subclinical neuropathology in healthy individuals with familial risk: A scoping review of MRI studies. In: Neuroimage-Clinical, Bd. 31, 102734

Macrini, Caterina; Gerhards, Ramona; Winklmeier, Stephan; Bergmann, Lena; Mader, Simone; Spadaro, Melania; Vural, Atay; Smolle, Michaela; Hohlfeld, Reinhard; Kuempfel, Tania; Lichtenthaler, Stefan F.; Franquelim, Henri G.; Jenne, Dieter und Meinl, Edgar (2021): Features of MOG required for recognition by patients with MOG antibody-associated disorders. In: Brain, Bd. 144: S. 2375-2389

Kappos, Ludwig; Fox, Robert J.; Burcklen, Michel; Freedman, Mark S.; Havrdova, Eva K.; Hennessy, Brian; Hohlfeld, Reinhard; Lublin, Fred; Montalban, Xavier; Pozzilli, Carlo; Scherz, Tatiana; D'Ambrosio, Daniele; Linscheid, Philippe; Vaclavkova, Andrea; Pirozek-Lawniczek, Magdalena; Kracker, Hilke und Sprenger, Till (2021): Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study A Randomized Clinical Trial. In: Jama Neurology, Bd. 78, Nr. 5: S. 558-567

Dangond, Fernando; Donnelly, Alexis; Hohlfeld, Reinhard; Lubetzki, Catherine; Kohlhaas, Susan; Leocani, Letizia; Ciccarelli, Olga; Stankoff, Bruno; Sormani, Maria Pia; Chataway, Jeremy; Bozzoli, Federico; Cucca, Francesco; Melton, Lisa; Coetzee, Timothy und Salvetti, Marco (2021): Facing the urgency of therapies for progressive MS - a Progressive MS Alliance proposal. In: Nature Reviews Neurology, Bd. 17, Nr. 3: S. 185-192

Braendle, Simone M.; Cerina, Manuela; Weber, Susanne; Held, Kathrin; Menke, Amelie F.; Alcala, Carmen; Gebert, David; Herrmann, Alexander M.; Pellkofer, Hannah; Gerdes, Lisa Ann; Bittner, Stefan; Leypoldt, Frank; Teegen, Bianca; Komorowski, Lars; Kuempfel, Tania; Hohlfeld, Reinhard; Meuth, Sven G.; Casanova, Bonaventura; Melzer, Nico; Beltran, Eduardo und Dornmair, Klaus (2021): Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABA(A) receptor encephalitis. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 9, e1916337118

Hohlfeld, Reinhard (2021): Correcting gut dysbiosis can ameliorate inflammation and promote remyelination in multiple sclerosis - Commentary. In: Multiple sclerosis, Bd. 27, Nr. 8: S. 1164-1165 [PDF, 62kB]

Thompson, Alan J.; Carroll, William; Ciccarelli, Olga; Comi, Giancarlo; Cross, Anne; Donnelly, Alexis; Feinstein, Anthony; Fox, Robert J.; Helme, Anne; Hohlfeld, Reinhard; Hyde, Robert; Kanellis, Pamela; Landsman, Douglas; Lubetzki, Catherine; Marrie, Ruth Ann; Morahan, Julia; Montalban, Xavier; Musch, Bruno; Rawlings, Sarah; Salvetti, Marco; Sellebjerg, Finn; Sincock, Caroline; Smith, Kathryn E.; Strum, Jon; Zaratin, Paola und Coetzee, Timothy (2021): Charting a global research strategy for progressive MS-An international progressive MS Alliance proposal. In: Multiple Sclerosis Journal, Bd. 28, Nr. 1, 13524585211059766: S. 16-28

Meinl, Edgar

und Hohlfeld, Reinhard (2021): CD20+ T Cells as Pathogenic Players and Therapeutic Targets in MS. In: Annals of Neurology, Bd. 90, Nr. 5: S. 722-724 [PDF, 84kB]

Bracher, Aline; Alcalá, Carmen; Ferrer, Jaime; Melzer, Nico; Hohlfeld, Reinhard; Casanova, Bonaventura; Beltrán, Eduardo und Dornmair, Klaus (2020): An expanded parenchymal CD8+ T cell clone in GABAA receptor encephalitis. In: Annals of Clinical and Translational Neurology, Bd. 7, Nr. 2: S. 239-244 [PDF, 1MB]

Penkert, Horst; Lauber, Chris; Gerl, Mathias J.; Klose, Christian; Damm, Markus; Fitzner, Dirk; Flierl-Hecht, Andrea; Kuempfel, Tania; Kerschensteiner, Martin; Hohlfeld, Reinhard; Gerdes, Lisa A. und Simons, Mikael (2020): Plasma lipidomics of monozygotic twins discordant for multiple sclerosis. In: Annals of Clinical and Translational Neurology, Bd. 7, Nr. 12: S. 2461-2466

Gerdes, Lisa Ann; Janoschka, Claudia; Eveslage, Maria; Mannig, Bianca; Wirth, Timo; Schulte-Mecklenbeck, Andreas; Lauks, Sarah; Glau, Laura; Gross, Catharina C.; Tolosa, Eva; Flierl-Hecht, Andrea; Ertl-Wagner, Birgit; Barkhof, Frederik; Meuth, Sven G.; Kuempfel, Tania; Wiendl, Heinz; Hohlfeld, Reinhard und Klotz, Luisa (2020): Immune signatures of prodromal multiple sclerosis in monozygotic twins. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 117, Nr. 35: S. 21546-21556

Comi, Giancarlo; Bar-Or, Amit; Lassmann, Hans; Uccelli, Antonio; Hartung, Hans-Peter; Montalban, Xavier; Sorensen, Per Solberg; Hohlfeld, Reinhard und Hauser, Stephen L. (2020): Role of B Cells in Multiple Sclerosis and Related Disorders. In: Annals of Neurology, Bd. 89, Nr. 1: S. 13-23

Gerhards, Ramona; Pfeffer, Lena Kristina; Lorenz, Jessica; Starost, Laura; Nowack, Luise; Thaler, Franziska S.; Schlueter, Miriam; Ruebsamen, Heike; Macrini, Caterina; Winklmeier, Stephan; Mader, Simone; Bronge, Mattias; Groenlund, Hans; Feederle, Regina; Hsia, Hung-En; Lichtenthaler, Stefan F.; Merl-Pham, Juliane; Hauck, Stefanie M.; Kuhlmann, Tanja; Bauer, Isabel J.; Beltran, Eduardo; Gerdes, Lisa Ann; Mezydlo, Aleksandra; Bar-Or, Amit; Banwell, Brenda; Khademi, Mohsen; Olsson, Tomas; Hohlfeld, Reinhard; Lassmann, Hans; Kuempfel, Tania; Kawakami, Naoto und Meinl, Edgar (2020): Oligodendrocyte myelin glycoprotein as a novel target for pathogenic autoimmunity in the CNS. In: Acta Neuropathologica Communications, Bd. 8, Nr. 1, 207

Fernandez, Iris Marti; Macrini, Caterina; Krumbholz, Markus; Hensbergen, Paul J.; Ederveen, Agnes L. Hipgrave; Winklmeier, Stephan; Vural, Atay; Kurne, Asli; Jenne, Dieter; Kamp, Frits; Gerdes, Lisa Ann; Hohlfeld, Reinhard; Wuhrer, Manfred; Kuempfel, Tania und Meinl, Edgar (11. Juni 2019): The Glycosylation Site of Myelin Oligodendrocyte Glycoprotein Affects Autoantibody Recognition in a Large Proportion of Patients. In: Frontiers in Immunology, Bd. 10, 1189: S. 1-10 [PDF, 717kB]

Beltran, Eduardo; Gerdes, Lisa Ann; Hansen, Julia; Flierl-Hecht, Andrea; Krebs, Stefan; Blum, Helmut; Ertl-Wagner, Birgit; Barkhof, Frederik; Kuempfel, Tania; Hohlfeld, Reinhard und Dornmair, Klaus (2019): Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis. In: Journal of Clinical Investigation, Bd. 129, Nr. 11: S. 4758-4768

Winklmeier, Stephan; Schlueter, Miriam; Spadaro, Melania; Thaler, Franziska S.; Vural, Atay; Gerhards, Ramona; Macrini, Caterina; Mader, Simone A.; Kurne, Asli; Inan, Berin; Karabudak, Rana; Ozbay, Feyza Gul; Esendagli, Gunes; Hohlfeld, Reinhard; Kuempfel, Tania und Meinl, Edgar (2019): Identification of circulating MOG-specific B cells in patients with MOG antibodies. In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 6, Nr. 6, e625

Souren, Nicole Y.; Gerdes, Lisa A.; Lutsik, Pavlo; Gasparoni, Gilles; Beltrán, Eduardo; Salhab, Abdulrahman; Kümpfel, Tania; Weichenhan, Dieter; Plass, Christoph; Hohlfeld, Reinhard und Walter, Jörn (2019): DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis. In: Nature Communications, Bd. 10, 2094: S. 1-12 [PDF, 793kB]

Konjevic Sabolek, Matea; Held, Kathrin; Beltrán, Eduardo; Niedl, Anna G.; Meinl, Edgar; Hohlfeld, Reinhard; Lassmann, Hans und Dornmair, Klaus (2019): Communication of CD8+ T cells with mononuclear phagocytes in multiple sclerosis. In: Annals of Clinical and Translational Neurology, Bd. 6, Nr. 7: S. 1151-1164 [PDF, 3MB]

Oertel, Frederike C.; Outteryck, Olivier; Knier, Benjamin; Zimmermann, Hanna; Borisow, Nadja; Bellmann-Strobl, Judith; Blaschek, Astrid; Jarius, Sven; Reindl, Markus; Ruprecht, Klemens; Meinl, Edgar; Hohlfeld, Reinhard; Paul, Friedemann; Brandt, Alexander U.; Kuempfel, Tania und Havla, Joachim (2019): Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study. In: Journal of Neuroinflammation, Bd. 16, 154

Gasperi, Christiane; Salmen, Anke; Antony, Gisela; Bayas, Antonios; Heesen, Christoph; Kuempfel, Tania; Linker, Ralf A.; Paul, Friedemann; Stangel, Martin; Tackenberg, Björn; Bergh, Florian Then; Warnke, Clemens; Weber, Frank; Wiendl, Heinz; Wildemann, Brigitte; Zettl, Uwe K.; Ziemann, Ulf; Zipp, Frauke; Tumani, Hayrettin; Gold, Ralf; Hemmer, Bernhard; Aktas, Orhan; Antony, Gisela; Ayzenberg, Ilya; Gold, Ralf; Hellwig, Kerstin; Salmen, Anke; Lukas, Carsten; Bahn, Erik; Brueck, Wolfgang; Fluegel, Alexander; Friede, Tim; Lodygin, Dmitri; Meissner, Tina; Berger, Klaus; Buck, Dorothea; Hemmer, Bernhard; Muehlau, Mark; Korn, Thomas; Friese, Manuel; Heesen, Christoph; Stellmann, Jan-Patrick; Groppa, Sergiu; Luessi, Felix; Zipp, Frauke; Gross, Catharina; Klotz, Luisa; Meuth, Sven; Ruck, Tobias; Wiendl, Heinz; Haas, Jürgen; Wildemann, Brigitte; Hohlfeld, Reinhard; Kerschensteiner, Martin; Kuempfel, Tania; Meinl, Edgar; Hohlfeld, Reinhard; Kerschensteiner, Martin; Korn, Thomas; Hemmer, Bernhard; König, Inke; Kowarik, Markus; Ziemann, Ulf; Krishnamoorthy, Gurumoorthy; Müller-Myhsok, Bertram; Nischwitz, Sandra; Müller-Myhsok, Bertram; Prinz, Marco; Salmen, Anke; Stangel, Martin; Trebst, Corinna; Tumani, Hayrettin; Bayas, Antonios; Hartung, Hans-Peter; Linker, Ralf; Nischwitz, Sandra; Paul, Friedemann; Tackenberg, Björn; Bergh, Florian Then und Zettl, Uwe (2019): Association of Intrathecal Immunoglobulin G Synthesis With Disability Worsening in Multiple Sclerosis. In: Jama Neurology, Bd. 76, Nr. 7: S. 841-849

Foerster, Moritz; Kuery, Patrick; Aktas, Orhan; Warnke, Clemens; Havla, Joachim; Hohlfeld, Reinhard; Mares, Jan; Hartung, Hans-Peter und Kremer, David (2019): Managing Risks with Immune Therapies in Multiple Sclerosis. In: Drug Safety, Bd. 42, Nr. 5: S. 633-647

Graetz, Christiane; Groeger, Adriane; Luessi, Felix; Salmen, Anke; Zoeller, Daniela; Schultz, Janine; Siller, Nelly; Fleischer, Vinzenz; Bellenberg, Barbara; Berthele, Achim; Biberacher, Viola; Havla, Joachim; Hecker, Michael; Hohlfeld, Reinhard; Infante-Duarte, Carmen; Kirschke, Jan S.; Kuempfel, Tania; Linker, Ralf; Paul, Friedemann; Pfeuffer, Steffen; Saemann, Philipp; Toenges, Gerrit; Weber, Frank; Zettl, Uwe K.; Jahn-Eimermacher, Antje; Antony, Gisela; Groppa, Sergiu; Wiendl, Heinz; Hemmer, Bernhard; Muehlau, Mark; Lukas, Carsten; Gold, Ralf; Lill, Christina M. und Zipp, Frauke (2019): Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis. In: Multiple Sclerosis Journal, Bd. 25, Nr. 5: S. 661-668

Klotz, Luisa; Havla, Joachim; Schwab, Nicholas; Hohlfeld, Reinhard; Barnett, Michael; Reddel, Stephen und Wiendl, Heinz (2019): Risks and risk management in modern multiple sclerosis immunotherapeutic treatment. In: Therapeutic Advances in Neurological Disorders, Bd. 12: S. 1-31 [PDF, 193kB]

Thaler, Franziska S.; Thaller, Anna L.; Biljecki, Michelle; Schuh, Elisabeth; Winklmeier, Stephan; Mahler, Christoph F.; Gerhards, Ramona; Voelk, Stefanie; Schnorfeil, Frauke; Subklewe, Marion; Hohlfeld, Reinhard; Kuempfel, Tania und Meinl, Edgar (2019): Abundant glutamic acid decarboxylase (GAD)-reactive B cells in gad-antibody-associated neurological disorders. In: Annals of Neurology, Bd. 85, Nr. 3: S. 448-454

Meinl, Ingrid; Havla, Joachim; Hohlfeld, Reinhard und Kuempfel, Tania (2018): Recurrence of disease activity during pregnancy after cessation of fingolimod in multiple sclerosis. In: Multiple Sclerosis Journal, Bd. 24, Nr. 7: S. 991-994 [PDF, 181kB]

Hohlfeld, Reinhard (2018): B-cells as therapeutic targets in neuro-inflammatory diseases. In: Clinical Immunology, Bd. 186: S. 51-53

Spadaro, Melania; Winklmeier, Stephan; Beltran, Eduardo; Macrini, Caterina; Hoeftberger, Romana; Schuh, Elisabeth; Thaler, Franziska S.; Gerdes, Lisa Ann; Laurent, Sarah; Gerhards, Ramona; Braendle, Simone; Dornmair, Klaus; Breithaupt, Constanze; Krumbholz, Markus; Moser, Markus; Krishnamoorthy, Gurumoorthy; Kamp, Frits; Jenne, Dieter; Hohlfeld, Reinhard; Kuempfel, Tania; Lassmann, Hans; Kawakami, Naoto und Meinl, Edgar (2018): Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein. In: Annals of Neurology, Bd. 84, Nr. 2: S. 315-328

Schuh, Elisabeth; Musumeci, Andrea; Thaler, Franziska S.; Laurent, Sarah; Ellwart, Joachim W.; Hohlfeld, Reinhard; Krug, Anne und Meinl, Edgar (2017): Human Plasmacytoid Dendritic Cells Display and Shed B Cell Maturation Antigen upon TLR Engagement. In: Journal of Immunology, Bd. 198, Nr. 8: S. 3081-3088

Berer, Kerstin; Gerdes, Lisa Ann; Cekanaviciute, Egle; Jia, Xiaoming; Xiao, Liang; Xia, Zhongkui; Liu, Chuan; Klotz, Luisa; Stauffer, Uta; Baranzini, Sergio E.; Kümpfel, Tania; Hohlfeld, Reinhard; Krishnamoorthy, Gurumoorthy und Wekerle, Hartmut (2017): Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 40: S. 10719-10724

Yshii, Lidia M.; Hohlfeld, Reinhard und Liblau, Roland S. (2017): Y Inflammatory CNS disease caused by immune checkpoint inhibitors: status and perspectives. In: Nature Reviews Neurology, Bd. 13, Nr. 12: S. 755-763

Hohlfeld, Reinhard und Meinl, Edgar (2017): Ocrelizumab in multiple sclerosis: markers and mechanisms. In: Lancet Neurology, Bd. 16, Nr. 4: S. 259-261

Hohlfeld, Reinhard; Havla, Joachim und Kümpfel, Tania (2017): Patient-to-patient transmission of natalizumab-associated PML? In: Multiple Sclerosis Journal, Bd. 23, Nr. 11: S. 1564-1565 [PDF, 49kB]

Ingrisch, Michael

; Sourbron, Steven; Herberich, Sina; Schneider, Moritz Jörg; Kümpfel, Tania; Hohlfeld, Reinhard; Reiser, Maximilian F. und Ertl-Wagner, Birgit (2017): Dynamic Contrast-Enhanced Magnetic Resonance Imaging Suggests Normal Perfusion in Normal-Appearing White Matter in Multiple Sclerosis. In: Investigative Radiology, Bd. 52, Nr. 3: S. 135-141 [PDF, 512kB]

Hohlfeld, Reinhard (2017): Stop inflammation and you stop neurodegeneration in MS - Commentary. In: Multiple Sclerosis Journal, Bd. 23, Nr. 10: S. 1323-1324

Havla, Joachim; Warnke, Clemens; Derfuss, Tobias; Kappos, Ludwig; Hartung, Hans-Peter und Hohlfeld, Reinhard (2016): Interdisciplinary Risk Management in the Treatment of Multiple Sclerosis. In: Deutsches Ärzteblatt international, Bd. 113, Nr. 51-52: S. 879-886

Rühl, Geraldine; Niedl, Anna G.; Patronov, Atanas; Siewert, Katherina; Pinkert, Stefan; Kalemanov, Maria; Friese, Manuel A.; Attfield, Kathrine E.; Antes, Iris; Hohlfeld, Reinhard und Dornmair, Klaus (2016): Multiple sclerosis Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor. In: Neurology: Neuroimmunology & Neuroinflammation, Bd. 3, Nr. 4, e241 [PDF, 730kB]

Hohlfeld, Reinhard und Kümpfel, Tania (2016): Alemtuzumab and Multiple Sclerosis Another Note of Caution. In: Jama Neurology, Bd. 73, Nr. 6: S. 637-638

Melzer, Nico; Ruck, Tobias; Fuhr, Peter; Gold, Ralf; Hohlfeld, Reinhard; Marx, Alexander; Melms, Arthur; Tackenberg, Björn; Schalke, Berthold; Schneider-Gold, Christiane; Zimprich, Fritz; Meuth, Sven G. und Wiendl, Heinz (2016): Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the Guidelines of the German Neurological Society. In: Journal of Neurology, Bd. 263, Nr. 8: S. 1473-1494

Hohlfeld, Reinhard; Dornmair, Klaus; Meinl, Edgar und Wekerle, Hartmut (2016): The search for the target antigens of multiple sclerosis, part 2: CD8+T cells, B cells, and antibodies in the focus of reverse-translational research. In: Lancet Neurology, Bd. 15, Nr. 3: S. 317-331

Hohlfeld, Reinhard; Dornmair, Klaus; Meinl, Edgar und Wekerle, Hartmut (2016): The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+T lymphocytes as pathogenic effectors and therapeutic targets. In: Lancet Neurology, Bd. 15, Nr. 2: S. 198-209

Brändle, Simone M.; Obermeier, Birgit; Senel, Makbule; Bruder, Jessica; Mentele, Reinhard; Khademi, Mohsen; Olsson, Tomas; Tumani, Hayrettin; Kristoferitsch, Wolfgang; Lottspeich, Friedrich; Wekerle, Hartmut; Hohlfeld, Reinhard und Dornmair, Klaus (2016): Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 113, Nr. 28: S. 7864-7869

Gross, Catharina C.; Schulte-Mecklenbeck, Andreas; Rünzi, Anna; Kuhlmann, Tanja; Posevitz-Fejfár, Anita; Schwab, Nicholas; Schneider-Hohendorf, Tilman; Herich, Sebastian; Held, Kathrin; Konjević, Matea; Hartwig, Marvin; Dornmair, Klaus; Hohlfeld, Reinhard; Ziemssen, Tjalf; Klotz, Luisa; Meuth, Sven G. und Wiendl, Heinz (2016): Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 113, Nr. 21, E2973-E2982

Sunderkötter, Cord; Nast, Alexander; Worm, Margitta; Dengler, Reinhard; Dörner, Thomas; Ganter, Horst; Hohlfeld, Reinhard; Melms, Arthur; Melzer, Nico; Rösler, Kai; Schmidt, Jens; Sinnreich, Michael; Walter, Maggi C.; Wanschitz, Julia und Wiendl, Heinz (2016): Guidelines on dermatomyositis excerpt from the interdisciplinary S2k guidelines on myositis syndromes by the German Society of Neurology. In: Journal Der Deutschen Dermatologischen Gesellschaft, Bd. 14, Nr. 3: S. 321-333

Gerdes, Lisa Ann; Held, Kathrin; Beltrán, Eduardo; Berking, Carola; Prinz, Jörg C.; Junker, Andreas; Tietze, Julia K.; Ertl-Wagner, Birgit; Straube, Andreas; Kümpfel, Tania; Dornmair, Klaus und Hohlfeld, Reinhard (2016): CTLA4 as Immunological Checkpoint in the Development of Multiple Sclerosis. In: Annals of Neurology, Bd. 80, Nr. 2: S. 294-300

Souren, Nicole Y. P.; Gerdes, Lisa A.; Kümpfel, Tania; Lutsik, Pavlo; Klopstock, Thomas; Hohlfeld, Reinhard und Walter, Jörn (2016): Mitochondrial DNA Variation and Heteroplasmy in Monozygotic Twins Clinically Discordant for Multiple Sclerosis. In: Human Mutation, Bd. 37, Nr. 8: S. 765-775

Hohlfeld, Reinhard und Schulze-Koops, Hendrik (2016): Cytotoxic T cells go awry in inclusion body myositis. In: Brain, Bd. 139: S. 1312-1314

Hohlfeld, Reinhard und Kerschensteiner, Martin (2016): Antiglutamatergic therapy for multiple sclerosis? In: Lancet Neurology, Bd. 15, Nr. 10: S. 1003-1004

Schwab, Nicholas; Schneider-Hohendorf, Tilman; Pignolet, Béatrice; Spadaro, Michela; Görlich, Dennis; Meinl, Ingrid; Windhagen, Susanne; Tackenberg, Björn; Breuer, Johanna; Cantó, Ester; Kümpfel, Tania; Hohlfeld, Reinhard; Siffrin, Volker; Luessi, Felix; Posevitz-Fejfár, Anita; Montalban, Xavier; Meuth, Sven G.; Zipp, Frauke; Gold, Ralf; Du Pasquier, Renaud A.; Kleinschnitz, Christoph; Jacobi, Annett; Comabella, Manuel; Bertolotto, Antonio; Brassat, David und Wiendl, Heinz (2016): PML risk stratification using anti-JCV antibody index and L-selectin. In: Multiple Sclerosis Journal, Bd. 22, Nr. 8: S. 1048-1060 [PDF, 1MB]

Schuh, Elisabeth; Berer, Kerstin; Mulazzani, Matthias; Feil, Katharina; Meinl, Ingrid; Lahm, Harald; Krane, Markus; Lange, Rüdiger; Pfannes, Kristina; Subklewe, Marion; Gürkov, Robert; Bradl, Monika; Hohlfeld, Reinhard; Kümpfel, Tania; Meinl, Edgar und Krumbholz, Markus (2016): Features of Human CD3(+)CD20(+) T Cells. In: Journal of Immunology, Bd. 197, Nr. 4: S. 1111-1117

Spadaro, Melania; Gerdes, Lisa Ann; Krumbholz, Markus; Ertl-Wagner, Birgit; Thaler, Franziska Sabrina; Schuh, Elisabeth; Metz, Imke; Blaschek, Astrid; Dick, Andrea; Brück, Wolfgang; Hohlfeld, Reinhard; Meinl, Edgar und Kümpfel, Tania (2016): Autoantibodies to MOG in a distinct subgroup of adult multiple sclerosis. In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 3, Nr. 5, e257 [PDF, 747kB]

Spadaro, Melania; Gerdes, Lisa Ann; Mayer, Marie C.; Ertl-Wagner, Birgit; Laurent, Sarah; Krumbholz, Markus; Breithaupt, Constanze; Högen, Tobias; Straube, Andreas; Giese, Armin; Hohlfeld, Reinhard; Lassmann, Hans; Meinl, Edgar und Kümpfel, Tania (2015): Histopathology and clinical course of MOG-antibody-associated encephalomyelitis. In: Annals of Clinical and Translational Neurology, Bd. 2, Nr. 3: S. 295-301

Laurent, Sarah A.; Hoffmann, Franziska S.; Kuhn, Peer-Hendrik; Cheng, Qingyu; Chu, Yuanyuan; Schmidt-Supprian, Marc; Hauck, Stefanie M.; Schuh, Elisabeth; Krumbholz, Markus; Ruebsamen, Heike; Wanngren, Johanna; Khademi, Mohsen; Olsson, Tomas; Alexander, Tobias; Hiepe, Falk; Pfister, Hans-Walter; Weber, Frank; Jenne, Dieter; Wekerle, Hartmut; Hohlfeld, Reinhard; Lichtenthaler, Stefan F. und Meinl, Edgar (2015): gamma-secretase directly sheds the survival receptor BCMA from plasma cells. In: Nature Communications, Bd. 6, 7333 [PDF, 1MB]

Wuhrer, Manfred; Selman, Maurice H. J.; McDonnell, Liam A.; Kümpfel, Tania; Derfuss, Tobias; Khademi, Mohsen; Olsson, Tomas; Hohlfeld, Reinhard; Meinl, Edgar und Krumbholz, Markus (2015): Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid. In: Journal of Neuroinflammation 12:235 [PDF, 1MB]

Hoffmann, Franziska S.; Hofereiter, Johann; Rübsamen, Heike; Melms, Johannes; Schwarz, Sigrid; Faber, Hans; Weber, Peter; Pütz, Benno; Loleit, Verena; Weber, Frank; Hohlfeld, Reinhard; Meinl, Edgar und Krumbholz, Markus (2015): Fingolimod induces neuroprotective factors in human astrocytes. In: Journal of Neuroinflammation 12:184 [PDF, 1MB]

Mohan, Hema; Friese, Anita; Albrecht, Stefanie; Krumbholz, Markus; Elliott, Christina L.; Arthur, Ariel; Menon, Ramesh; Farina, Cinthia; Junker, Andreas; Stadelmann, Christine; Barnett, Susan C; Huitinga, Inge; Wekerle, Hartmut; Hohlfeld, Reinhard; Lassmann, Hans; Kuhlmann, Tanja; Linington, Chris und Meinl, Edgar (11. Dezember 2014): Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination. In: Acta Neuropathologica Communications 2:178 [PDF, 2MB]

Warnke, Clemens; Stettner, Mark; Lehmensiek, Vera; Dehmel, Thomas; Mausberg, Anne K.; Geldern, Gloria von; Gold, Ralf; Kümpfel, Tania; Hohlfeld, Reinhard; Mäurer, Mathias; Stangel, Martin; Straeten, Vera; Limmroth, Volker; Weber, Thomas; Kleinschnitz, Christoph; Wattjes, Mike P.; Svenningsson, Anders; Olsson, Tomas; Hartung, Hans-Peter; Hermsen, Derik; Tumani, Hayrettin; Adams, Ortwin und Kieseier, Bernd C. (2014): Natalizumab exerts a suppressive effect on surrogates of B cell function in blood and CSF. In: Multiple Sclerosis Journal, Bd. 21, Nr. 8: S. 1036-1044 [PDF, 407kB]

Hoepner, Robert; Havla, Joachim; Eienbröker, Christian; Tackenberg, Björn; Hellwig, Kerstin; Meinl, Ingrid; Hohlfeld, Reinhard; Gold, Ralf; Kümpfel, Tania und Kleiter, Ingo (2014): Predictors for multiple sclerosis relapses after switching from natalizumab to fingolimod. In: Multiple Sclerosis Journal, Bd. 20, Nr. 13: S. 1714-1720 [PDF, 115kB]

Hohlfeld, Reinhard (Oktober 2013): Natalizumab-induced PML: can the beast be tamed? In: Journal of Neurology, Neurosurgery and Psychiatry, Bd. 84, Nr. 10: S. 1065 [PDF, 93kB]

Havla, Joachim; Berthele, A.; Kümpfel, Tania; Krumbholz, Markus; Jochim, A.; Kronsbein, H.; Ryschkewitsch, C.; Jensen, P.; Lippmann, K.; Hemmer, B.; Major, E. und Hohlfeld, Reinhard (August 2013): Co-occurrence of two cases of progressive multifocal leukoencephalopathy in a natalizumab ``infusion group''. In: Multiple Sclerosis Journal, Bd. 19, Nr. 9: S. 1213-1215 [PDF, 638kB]

Ertl-Wagner, Birgit; Koerte, Inga; Kümpfel, Tania; Blaschek, Astrid; Laubender, Rüdiger P.; Schick, Max; Steffinger, Denise; Kaufmann, David; Heinen, Florian; Reiser, Maximilian; Alperin, Noam und Hohlfeld, Reinhard (2012): Non-specific alterations of craniocervical venous drainage in multiple sclerosis revealed by cardiac-gated phase-contrast MRI. In: Multiple Sclerosis, Bd. 18, Nr. 7: S. 1000-1007

Lehmann-Horn, Klaus; Schleich, Eva; Hertzenberg, Deetje; Hapfelmeier, Alexander; Kümpfel, Tania; Bubnoff, Nikolas von; Hohlfeld, Reinhard; Berthele, Achim; Hemmer, Bernhard und Weber, Martin S. (2011): Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders. In: Journal of Neuroinflammation 8:146 [PDF, 490kB]

Hohlfeld, Reinhard (2010): Review: ‘Gimme five’: future challenges in multiple sclerosis. ECTRIMS Lecture 2009. In: Multiple Sclerosis, Bd. 16, Nr. 1: S. 3-14 [PDF, 913kB]

Clanet, M.; Kappos, L.; Hartung, H.-P. und Hohlfeld, Reinhard (2004): Interferon β-1a in relapsing multiple sclerosis: four-year extension of the European IFNβ-1a Dose-C omparison Study. In: Multiple Sclerosis, Bd. 10, Nr. 2: S. 139-144 [PDF, 240kB]

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