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Anzahl der Publikationen: 62
Zeitschriftenartikel
Kogan, Palgit-S.; Wirth, Felix; Tomar, Archana; Darr, Jonatan; Teperino, Raffaele; Lahm, Harald; Dressen, Martina; Puluca, Nazan; Zhang, Zhong; Neb, Irina; Beck, Nicole; Luzius, Tatjana; Osa de la Rosa, Luis de la; Gärtner, Kathrin; Hüls, Corinna; Zeidler, Reinhard; Ramanujam, Deepak; Engelhardt, Stefan; Wenk, Catharina; Holdt, Lesca M.; Mononen, Mimmi; Sahara, Makoto; Cleuziou, Julie; Hörer, Jürgen; Lange, Rüdiger; Krane, Markus und Doppler, Stefanie A.
(2022):
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing.
In: Basic Research in Cardiology, Bd. 117, Nr. 1, 11
Spix, Barbara; Butz, Elisabeth S.; Chen, Cheng-Chang; Rosato, Anna Scotto; Tang, Rachel; Jeridi, Aicha; Kudrina, Veronika; Plesch, Eva; Wartenberg, Philipp; Arlt, Elisabeth; Briukhovetska, Daria; Ansari, Meshal; Günsel, Gizem Günes; Conlon, Thomas M.; Wyatt, Amanda; Wetzel, Sandra; Teupser, Daniel; Holdt, Lesca M.; Ectors, Fabien; Boekhoff, Ingrid; Boehm, Ulrich; García-Añoveros, Jaime; Saftig, Paul; Giera, Martin; Kobold, Sebastian; Schiller, Herbert B.; Zierler, Susanna; Gudermann, Thomas; Wahl-Schott, Christian; Bracher, Franz; Yildirim, Ali Önder; Biel, Martin und Grimm, Christian
(2022):
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.
In: Nature Communications, Bd. 13, 318
[PDF, 3MB]
Jodeleit, Henrika; Winkelmann, Paula; Caesar, Janina; Sterz, Sebastian; Holdt, Lesca M.; Beigel, Florian; Stallhofer, Johannes; Breiteneicher, Simone; Bartnik, Eckart; Leeuw, Thomas; Siebeck, Matthias 
ORCID: https://orcid.org/0000-0001-5290-5344 und Gropp, Roswitha ORCID: https://orcid.org/0000-0003-4756-261X
(2021):
Head-to-head study of oxelumab and adalimumab in a mouse model of ulcerative colitis based on NOD/Scid IL2Rγnull mice reconstituted with human peripheral blood mononuclear cells.
In: Disease Models & Mechanisms, Bd. 14, Nr. 1, dmm046995
[PDF, 3MB]
ORCID: https://orcid.org/0000-0001-5290-5344 und Gropp, Roswitha ORCID: https://orcid.org/0000-0003-4756-261X
(2021):
Head-to-head study of oxelumab and adalimumab in a mouse model of ulcerative colitis based on NOD/Scid IL2Rγnull mice reconstituted with human peripheral blood mononuclear cells.
In: Disease Models & Mechanisms, Bd. 14, Nr. 1, dmm046995
[PDF, 3MB]
Buchholtz, Marie-Luise; Arend, Florian M.; Eichhorn, Peter; Weigand, Michael; Kleinhempel, Alisa; Häusler, Kurt; Bruegel, Mathias; Holdt, Lesca M. und Teupser, Daniel
(2021):
SARS-CoV-2 antibody immunoassays in serial samples reveal earlier seroconversion in acutely ill COVID-19 patients developing ARDS.
In: PLOS One 16(5), e0251587
In: PLOS One 16(5), e0251587
Gabel, Gabor; Northoff, Bernd H.; Balboa, Amanda; Becirovic-Agic, Mediha; Petri, Marcelo; Busch, Albert; Maegdefessel, Lars; Mahlmann, Adrian; Ludwig, Stefan; Teupser, Daniel; de Waard, Vivian; Golledge, Jonathan; Wanhainen, Anders; Wagsater, Dick; Holdt, Lesca M. und Lindeman, Jan H. N.
(2021):
Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression.
In: Journal of the American Heart Association, Bd. 10, Nr. 17, e020231
Geyer, Philipp E.; Arend, Florian M.; Doll, Sophia; Louiset, Marie-Luise; Winter, Sebastian Virreira; Müller-Reif, Johannes B.; Torun, Furkan M.; Weigand, Michael; Eichhorn, Peter; Brügel, Mathias; Strauss, Maximilian T.; Holdt, Lesca M.; Mann, Matthias und Teupser, Daniel
(2021):
High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion.
In: EMBO Molecular Medicine, Bd. 13, Nr. 8, e14167
Jodeleit, Henrika; Winkelmann, Paula; Caesar, Janina; Sterz, Sebastian; Holdt, Lesca M.; Beigel, Florian; Stallhofer, Johannes; Breiteneicher, Simone; Bartnik, Eckart; Leeuw, Thomas; Siebeck, Matthias und Gropp, Roswitha
(2021):
Head-to-head study of oxelumab and adalimumab in a mouse reconstituted with human peripheral blood mononuclear cells.
In: Disease Models & Mechanisms, Bd. 14, Nr. 1
Krane, Markus; Dressen, Martina; Santamaria, Gianluca; My, Ilaria; Schneider, Christine M.; Dorn, Tatjana; Laue, Svenja; Mastantuono, Elisa; Berutti, Riccardo; Rawat, Hilansi; Gilsbach, Ralf; Schneider, Pedro; Lahm, Harald; Schwarz, Sascha; Doppler, Stefanie A.; Paige, Sharon; Puluca, Nazan; Doll, Sophia; Neb, Irina; Brade, Thomas; Zhang, Zhong; Abou-Ajram, Claudia; Northoff, Bernd; Holdt, Lesca M.; Sudhop, Stefanie; Sahara, Makoto; Goedel, Alexander; Dendorfer, Andreas; Tjong, Fleur V. Y.; Rijlaarsdam, Maria E.; Cleuziou, Julie; Lang, Nora; Kupatt, Christian; Bezzina, Connie; Lange, Rudiger; Bowles, Neil E.; Mann, Matthias; Gelb, Bruce D.; Crotti, Lia; Hein, Lutz; Meitinger, Thomas; Wu, Sean; Sinnecker, Daniel; Gruber, Peter J.; Laugwitz, Karl-Ludwig und Moretti, Alessandra
(2021):
Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome.
In: Circulation, Bd. 144, Nr. 17: S. 1409-1428
Lokerse, Wouter J. M.; Lazarian, Artur; Kleinhempel, Alisa; Petrini, Matteo; Schwarz, Patricia; Hossann, Martin; Holdt, Lesca M.; Mailänder, Volker und Lindner, Lars H.
(2021):
Mechanistic investigation of thermosensitive liposome immunogenicity and understanding the drivers for circulation half-life: A polyethylene glycol versus 1,2-dipalmitoyl-sn-glycero-3-phosphodiglycerol study.
In: Journal of Controlled Release, Bd. 333: S. 1-15
Schmidt, Frank M.; Mergl, Roland; Minkwitz, Juliane; Holdt, Lesca M.; Teupser, Daniel; Hegerl, Ulrich; Himmerich, Hubertus und Sander, Christian
(25. Juni 2020):
Is There an Association or Not?—Investigating the Association of Depressiveness, Physical Activity, Body Composition and Sleep With Mediators of Inflammation.
In: Frontiers in Psychiatry, Bd. 11, 563: S. 1-11
[PDF, 518kB]
Sadler, Rebecca; Cramer, Julia V.; Heindl, Steffanie; Kostidis, Sarantos; Betz, Dene; Zuurbier, Kielen R.; Northoff, Bernd H.; Heijink, Marieke; Goldberg, Mark P.; Plautz, Erik J.; Roth, Stefan; Malik, Rainer; Dichgans, Martin; Holdt, Lesca M.; Benakis, Corinne; Giera, Martin; Stowe, Ann M. und Liesz, Arthur
(2020):
Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms.
In: Journal of Neuroscience, Bd. 40, Nr. 5: S. 1162-1173
Kouwenhoven, Stefanie M. P.; Antl, Nadja; Finken, Martijn J. J.; Twisk, Jos W. R.; Beek, Eline M. van der; Abrahamse-Berkeveld, Marieke; Heijning, Bert J. M. van de; Schierbeek, Henk; Holdt, Lesca M.; Goudoever, Johannes B. van und Koletzko, Berthold V.
(2020):
A modified low-protein infant formula supports adequate growth in healthy, term infants: a randomized, double-blind, equivalence trial.
In: American Journal of Clinical Nutrition, Bd. 111, Nr. 5: S. 962-974
Bux, Esther Marie; Solis-Mezarino, Victor; Kuhm, Christoph; Northoff, Bernd H.; Karin, Ivan; Klopstock, Thomas; Holdt, Lesca M.; Voelker-Albert, Moritz; Imhof, Axel und Peleg, Shahaf
(2020):
Determining histone H4 acetylation patterns in human peripheral blood mononuclear cells using mass spectrometry.
In: Clinical Mass Spectrometry, Bd. 15: S. 54-60
Grützner, Eva M.; Neizert, Ashley; Stirner, Renate; Conca, Raffaele; Andrä, Immanuel; Wolff, Lisa; Schiemann, Matthias; Holdt, Lesca M.; Klein, Christoph; Bogner, Johannes R. und Draenert, Rika
(2020):
High frequencies of PMN-MDSCs are associated with low suppressive capacity in advanced stages of HIV-1 infection.
In: Translational Medicine Communications
5:1
[PDF, 1MB]
Tiedt, Steffen; Brandmaier, Stefan; Kollmeier, Hanna; Duering, Marco; Artati, Anna; Adamski, Jerzy; Klein, Matthias; Liebig, Thomas; Holdt, Lesca M.; Teupser, Daniel; Wang‐Sattler, Rui; Schwedhelm, Edzard; Gieger, Christian und Dichgans, Martin
(2020):
Circulating Metabolites Differentiate Acute Ischemic Stroke from Stroke Mimics.
In: Annals of Neurology, Bd. 88, Nr. 4
[PDF, 1MB]
Holdt, Lesca M.; Kohlmaier, Alexander und Teupser, Daniel
(2019):
Long Noncoding RNAs of the Arterial Wall as Therapeutic Agents and Targets in Atherosclerosis.
In: Thrombosis and Haemostasis, Bd. 119, Nr. 8: S. 1222-1236
Schmidt, Frank M.; Koch, Jenny; Nowak, Claudia; Holdt, Lesca M.; Teupser, Daniel; Hegerl, Ulrich und Himmeric, Hubertus
(2019):
Ligands and receptors of the TNF superfamily are decreased in major depression and during early antidepressant therapy.
In: Journal of Psychiatric Research, Bd. 119: S. 116-121
Geyer, Philipp E.; Voytik, Eugenia; Treit, Peter V.; Doll, Sophia; Kleinhempel, Alisa; Niu, Lili; Müller, Johannes B.; Buchholtz, Marie-Luise; Bader, Jakob M.; Teupser, Daniel; Holdt, Lesca M. und Mann, Matthias
(2019):
Plasma Proteome Profiling to detect and avoid sample-related biases in biomarker studies.
In: EMBO Molecular Medicine, e10427
Hennessy, Elizabeth J.; van Solingen, Coen; Scacalossi, Kaitlyn R.; Ouimet, Mireille; Afonso, Milessa S.; Prins, Jurrien; Koelwyn, Graeme J.; Sharma, Monika; Ramkhelawon, Bhama; Carpenter, Susan; Busch, Albert; Chernogubova, Ekaterina; Matic, Ljubica Perisic; Hedin, Ulf; Maegdefessel, Lars; Caffrey, Brian E.; Hussein, Maryem A.; Ricci, Emiliano P.; Temel, Ryan E.; Garabedian, Michael J.; Berger, Jeffrey S.; Vickers, Kasey C.; Kanke, Matthew; Sethupathy, Praveen; Teupser, Daniel; Holdt, Lesca M. und Moore, Kathryn J.
(2019):
The long noncoding RNA CHROME regulates cholesterol homeostasis in primates.
In: Nature Metabolism, Bd. 1, Nr. 1: S. 98-110
Kokje, Vivianne B. C.; Gäbel, Gabor; Dalman, Ron L.; Koole, Dave; Northoff, Bernd H.; Holdt, Lesca M.; Hamming, Jaap F. und Lindeman, Jan H. N.
(2018):
CXCL8 hyper-signaling in the aortic abdominal aneurysm.
In: Cytokine, Bd. 108: S. 96-104
Doderer, Stefan A.; Gäbel, Gabor; Kokje, Vivienne B. C.; Northoff, Bernd H.; Holdt, Lesca M.; Hamming, Jaap F. und Lindeman, Jan H. N.
(2018):
Adventitial adipogenic degeneration is an unidentified contributor to aortic wall weakening in the abdominal aortic aneurysm.
In: Journal of Vascular Surgery, Bd. 67, Nr. 6: S. 1891-1900
Schmidt, Frank M.; Sander, Christian; Minkwitz, Juliane; Mergl, Roland; Dalton, Bethan; Holdt, Lesca M.; Teupser, Daniel; Hegerl, Ulrich und Himmerich, Hubertus
(2018):
Serum Markers of Inflammation Mediate the Positive Association Between Neuroticism and Depression.
In: Frontiers in Psychiatry, Bd. 9, 609
[PDF, 440kB]
Nicolaou, Alexandros; Northoff, Bernd H.; Zhao, Zhen; Kohlmaier, Alexander; Sass, Kristina; Rose-John, Stefan; Steffens, Sabine; Weber, Christian; Teupser, Daniel und Holdt, Lesca M.
(2018):
The ADAM17 Metalloproteinase Maintains Arterial Elasticity.
In: Thrombosis and Haemostasis, Bd. 118, Nr. 1: S. 210-213
Kassumeh, Stefan A.; Wertheimer, Christian M.; Studnitz, Annabel von; Hillenmayer, Anna; Priglinger, Claudia; Wolf, Armin; Mayer, Wolfgang J.; Teupser, Daniel; Holdt, Lesca M.; Priglinger, Siegfried G. und Eibl-Lindner, Kirsten H.
(2018):
Poly(lactic-co-glycolic) Acid as a Slow-Release Drug-Carrying Matrix for Methotrexate Coated onto Intraocular Lenses to Conquer Posterior Capsule Opacification.
In: Current Eye Research, Bd. 43, Nr. 6: S. 702-708
Holdt, Lesca M.; Kohlmaier, Alexander und Teupser, Daniel
(2018):
Molecular roles and function of circular RNAs in eukaryotic cells.
In: Cellular and Molecular Life Sciences, Bd. 75, Nr. 6: S. 1071-1098
Holdt, Lesca M. und Teupser, Daniel
(2018):
Long Noncoding RNA ANRIL: Lnc-ing Genetic Variation at the Chromosome 9p21 Locus to Molecular Mechanisms of Atherosclerosis.
In: Frontiers in Cardiovascular Medicine, Bd. 5, 145
[PDF, 1MB]
Plesch, Eva; Chen, Cheng-Chang; Butz, Elisabeth; Rosato, Anna Scotto; Krogsaeter, Einar K.; Yinan, Hua; Bartel, Karin; Keller, Marco; Robaa, Dina; Teupser, Daniel; Holdt, Lesca M.; Vollmar, Angelika M.; Sippl, Wolfgang; Puertollano, Rosa; Medina, Diego; Biel, Martin; Wahl-Schott, Christian; Bracher, Franz und Grimm, Christian
(2018):
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells.
In: eLife, Bd. 7, e39720
[PDF, 4MB]
Franceschini, Nora; Giambartolomei, Claudia; Vries, Paul S. de; Finan, Chris; Bis, Joshua C.; Huntley, Rachael P.; Lovering, Ruth C.; Tajuddin, Salman M.; Winkler, Thomas W.; Graff, Misa; Kavousi, Maryam; Dale, Caroline; Smith, Albert V.; Hofer, Edith; Leeuwen, Elisabeth M. van; Nolte, Ilja M.; Lu, Lingyi; Scholz, Markus; Sargurupremraj, Muralidharan; Pitkanen, Niina; Franzen, Oscar; Joshi, Peter K.; Noordam, Raymond; Marioni, Riccardo E.; Hwang, Shih-Jen; Musani, Solomon K.; Schminke, Ulf; Palmas, Walter; Isaacs, Aaron; Correa, Adolfo; Zonderman, Alan B.; Hofman, Albert; Teumer, Alexander; Cox, Amanda J.; Uitterlinden, Andre G.; Wong, Andrew; Smit, Andries J.; Newman, Anne B.; Britton, Annie; Ruusalepp, Arno; Sennblad, Bengt; Hedblad, Bo; Pasaniuc, Bogdan; Penninx, Brenda W.; Langefeld, Carl D.; Wassel, Christina L.; Tzourio, Christophe; Fava, Cristiano; Baldassarre, Damiano; O'Leary, Daniel H.; Teupser, Daniel; Kuh, Diana; Tremoli, Elena; Mannarino, Elmo; Grossi, Enzo; Börwinkle, Eric; Schadt, Eric E.; Ingelsson, Erik; Veglia, Fabrizio; Rivadeneira, Fernando; Beutner, Frank; Chauhan, Ganesh; Heiss, Gerardo; Snieder, Harold; Campbell, Harry; Völzke, Henry; Markus, Hugh S.; Deary, Ian J.; Jukema, J. Wouter; Graaf, Jacqueline de; Price, Jacqueline; Pott, Janne; Hopewell, Jemma C.; Liang, Jingjing; Thiery, Joachim; Engmann, Jorgen; Gertow, Karl; Rice, Kenneth; Taylor, Kent D.; Dhana, Klodian; Kiemeney, Lambertus A. L. M.; Lind, Lars; Raffield, Laura M.; Launer, Lenore J. und Holdt, Lesca M.
(2018):
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
In: Nature Communications, Bd. 9, 5141
[PDF, 1MB]
Roth, Stefan; Singh, Vikramjeet; Tiedt, Steffen; Schindler, Lisa; Huber, Georg; Geerlof, Arie; Antoine, Daniel J.; Anfray, Antoine; Orset, Cyrille; Gauberti, Maxime; Fournier, Antoine; Holdt, Lesca M.; Harris, Helena Erlandsson; Engelhardt, Britta; Bianchi, Marco E.; Vivien, Denis; Haffner, Christof; Bernhagen, Jürgen; Dichgans, Martin und Liesz, Arthur
(2018):
Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke.
In: Science Translational Medicine, Bd. 10, Nr. 432, eaao1313
Gomes, Delphina; Kries, Rüdiger von; Delius, Maria; Mansmann, Ulrich; Nast, Martha; Stubert, Martina; Langhammer, Lena; Haas, Nikolaus A.; Netz, Heinrich; Obermeier, Viola; Kuhle, Stefan; Holdt, Lesca M.; Teupser, Daniel; Hasbargen, Uwe; Roscher, Adelbert A. und Ensenauer, Regina
(2018):
Late-pregnancy dysglycemia in obese pregnancies after negative testing for gestational diabetes and risk of future childhood overweight: An interim analysis from a longitudinal mother-child cohort study.
In: PLOS Medicine 15(10), e1002681 [PDF, 1MB]
In: PLOS Medicine 15(10), e1002681 [PDF, 1MB]
Pott, Janne; Burkhardt, Ralph; Beutner, Frank; Horn, Katrin; Teren, Andrej; Kirsten, Holger; Holdt, Lesca M.; Schuler, Gerhard; Teupser, Daniel; Löffler, Markus; Thiery, Joachim und Scholz, Markus
(2017):
Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery.
In: Atherosclerosis, Bd. 259: S. 32-40
Georgi, Enrico; Walter, Mathias C.; Pfalzgraf, Marie-Theres; Northoff, Bernd H.; Holdt, Lesca M.; Scholz, Holger C.; Zöller, Lothar; Zange, Sabine und Antwerpen, Markus H.
(2017):
Whole genome sequencing of Brucella melitensis isolated from 57 patients in Germany reveals high diversity in strains from Middle East.
In: PLOS One 12(4), e0175425 [PDF, 7MB]
In: PLOS One 12(4), e0175425 [PDF, 7MB]
Herbst, Andreas; Vdovin, Nikolay; Gacesa, Sanja; Philipp, Alexander; Nagel, Dorothea; Holdt, Lesca M.; Winkel, Mark op den; Heinemann, Volker; Stieber, Petra; Graeven, Ullrich; Reinacher-Schick, Anke; Arnold, Dirk; Ricard, Ingrid; Mansmann, Ulrich; Hegewisch-Becker, Susanna und Kolligs, Frank T.
(2017):
Methylated free-circulating HPP1 DNA is an early response marker in patients with metastatic colorectal cancer.
In: International Journal of Cancer, Bd. 140, Nr. 9: S. 2134-2144
Winkels, Holger; Meiler, Svenja; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Hartwig, Helene; Holdt, Lesca M.; Hristov, Michael; Megens, Remco T. A.; Schmitt, Martin M.; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther und Gerdes, Norbert
(2017):
CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice.
In: European Heart Journal, Bd. 38, Nr. 48:
3590-U42
Nicolaou, Alexandros; Zhao, Zhen; Northoff, Bernd H.; Sass, Kristina; Herbst, Andreas; Kohlmaier, Alexander; Chalaris, Athena; Wolfrum, Christian; Weber, Christian; Steffens, Sabine; Rose-John, Stefan; Teupser, Daniel und Holdt, Lesca M.
(2017):
Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in Mice.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 37, Nr. 2: S. 247-257
Winkels, Holger; Meiler, Svenja; Smeets, Esther; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Rinne, Petteri; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Bossche, Jan van den; Holdt, Lesca M.; Megens, Remco T. A.; Schmitt, Martin M.; Winther, Menno de; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther und Gerdes, Norbert
(2017):
CD70 limits atherosclerosis and promotes macrophage function.
In: Thrombosis and Haemostasis, Bd. 117, Nr. 1: S. 164-175
Nicolaou, Alexandros; Northoff, Bernd H.; Sass, Kristina; Ernst, Jana; Kohlmaier, Alexander; Krohn, Knut; Wolfrum, Christian; Teupser, Daniel und Holdt, Lesca M.
(2017):
Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier.
In: Atherosclerosis, Bd. 265: S. 197-206
Vorst, Emiel P. C. van der; Zhao, Zhen; Rami, Martina; Holdt, Lesca M.; Teupser, Daniel; Steffens, Sabine und Weber, Christian
(2017):
Contrasting effects of myeloid and endothelial ADAM17 on atherosclerosis development.
In: Thrombosis and Haemostasis, Bd. 117, Nr. 3: S. 644-646
Drefs, Moritz; Thomas, Michael N.; Guba, Markus; Angele, Martin K.; Werner, Jens; Conrad, Marcus; Steib, Christian J.; Holdt, Lesca M.; Andrassy, Joachim; Khandoga, Andrej und Rentsch, Markus
(2017):
Modulation of Glutathione Hemostasis by Inhibition of 12/15-Lipoxygenase Prevents ROS-Mediated Cell Death after Hepatic Ischemia and Reperfusion.
In: Oxidative Medicine and Cellular Longevity, 8325754
[PDF, 2MB]
Willecke, Florian; Gissler, Mark Colin; Michel, Nathaly Anto; Pfeiffer, Katharina; Haertner, Carmen; Hilgendorf, Ingo; Wolf, Dennis; Stachon, Peter; Lutgens, Esther; Holdt, Lesca M.; Bode, Christoph; Gerdes, Norbert und Zirlik, Andreas Zirlik
(2017):
CD40 deficiency in smooth muscle cells ameliorates atherogenesis and promotes a stable plaque phenotype in the aortic root.
In: Atherosclerosis, Bd. 263, E62-E63
Döring, Yvonne; Noels, Heidi; Vorst, Emiel P. C. van der; Neideck, Carlos; Egea, Virginia; Drechsler, Maik; Mandl, Manuela; Pawig, Lukas; Jansen, Yvonne; Schröder, Katrin; Bidzhekov, Kiril; Megens, Remco T. A.; Theelen, Wendy; Klinkhammer, Barbara M.; Boor, Peter; Schurgers, Leon; Gorp, Rick van; Ries, Christian; Kusters, Pascal J. H.; Wal, Allard van der; Hackeng, Tilman M.; Gäbel, Gabor; Brandes, Ralf P.; Söhnlein, Oliver; Lutgens, Esther; Vestweber, Dietmar; Teupser, Daniel; Holdt, Lesca M.; Rader, Daniel J.; Saleheen, Danish und Weber, Christian
(2017):
Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity Evidence From Mouse and Human Studies.
In: Circulation, Bd. 136, Nr. 4: S. 388-403
[PDF, 3MB]
Geyer, Philipp E.; Holdt, Lesca M.; Teupser, Daniel und Mann, Matthias
(2017):
Revisiting biomarker discovery by plasma proteomics.
In: Molecular Systems Biology, Bd. 13, Nr. 9, 942
Schmidt, Frank M.; Pschiebl, Annika; Sander, Christian; Kirkby, Kenneth C.; Thormann, Julia; Minkwitz, Juliane; Chittka, Tobias; Weschenfelder, Julia; Holdt, Lesca M.; Teupser, Daniel; Hegerl, Ulrich und Himmerich, Hubertus
(2016):
Impact of Serum Cytokine Levels on EEG-Measured Arousal Regulation in Patients with Major Depressive Disorder and Healthy Controls.
In: Neuropsychobiology, Bd. 73, Nr. 1: S. 1-9
[PDF, 172kB]
Bernhart, Stephan H.; Kretzmer, Helene; Holdt, Lesca M.; Jühling, Frank; Ammerpohl, Ole; Bergmann, Anke K.; Northoff, Bernd H.; Doose, Gero; Siebert, Reiner; Stadler, Peter F. und Hoffmann, Steve
(2016):
Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer.
In: Scientific Reports, Bd. 6, 37393
[PDF, 2MB]
Marzi, Carola; Holdt, Lesca M.; Fiorito, Giovanni; Tsai, Pei-Chien; Kretschmer, Anja; Wahl, Simone; Guarrera, Simonetta; Teupser, Daniel; Spector, Tim D.; Iacoviello, Licia; Sacerdote, Carlotta; Strauch, Konstantin; Lee, Serene; Thasler, Wolfgang E.; Peters, Annette; Thorand, Barbara; Wolf, Petra; Prokisch, Holger; Tumino, Rosario; Gieger, Christian; Krogh, Vittorio; Panico, Salvatore; Bell, Jordana T.; Matullo, Giuseppe; Waldenberger, Melanie; Grallert, Harald und Koenig, Wolfgang
(2016):
Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues.
In: PLOS ONE 11(11), e0166015 [PDF, 1MB]
In: PLOS ONE 11(11), e0166015 [PDF, 1MB]
Holdt, Lesca M.; Stahringer, Anika; Sass, Kristina; Pichler, Garwin; Kulak, Nils A.; Wilfert, Wolfgang; Kohlmaier, Alexander; Herbst, Andreas; Northoff, Bernd H.; Nicolaou, Alexandros; Gäbel, Gabor; Beutner, Frank; Scholz, Markus; Thiery, Joachim; Musunuru, Kiran; Krohn, Knut; Mann, Matthias und Teupser, Daniel
(2016):
Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans.
In: Nature Communications, Bd. 7, 12429
[PDF, 1MB]
Hennig, Georg; Homann, Christian; Teksan, Ilknur; Hasbargen, Uwe; Hasmüller, Stephan; Holdt, Lesca M.; Khaled, Nadia; Sroka, Ronald; Stauch, Thomas; Stepp, Herbert; Vogeser, Michael und Brittenham, Gary M.
(2016):
Non-invasive detection of iron deficiency by fluorescence measurement of erythrocyte zinc protoporphyrin in the lip.
In: Nature Communications, Bd. 7, 10776
[PDF, 526kB]
Geyer, Philipp E.; Kulak, Nils A.; Pichler, Garwin; Holdt, Lesca M.; Teupser, Daniel und Mann, Matthias
(2016):
Plasma Proteome Profiling to Assess Human Health and Disease.
In: Cell Systems, Bd. 2, Nr. 3: S. 185-195
Kokje, Vivianne B. C.; Gäbel, Gabor; Koole, Dave; Northoff, Bernd H.; Holdt, Lesca M.; Hamming, Jaap F. und Lindeman, Jan H. N.
(2016):
IL-6: A Janus-like factor in abdominal aortic aneurysm disease.
In: Atherosclerosis, Bd. 251: S. 139-146
Schmidt, Frank M.; Schröder, Thomas; Kirkby, Kenneth C.; Sander, Christian; Suslow, Thomas; Holdt, Lesca M.; Teupser, Daniel; Hegerl, Ulrich und Himmerich, Hubertus
(2016):
Pro- and anti-inflammatory cytokines, but not CRP, are inversely correlated with severity and symptoms of major depression.
In: Psychiatry Research, Bd. 239: S. 85-91
Ouimet, Mireille; Hennessy, Elizabeth J.; Solingen, Coen van; Koelwyn, Graeme J.; Hussein, Maryem A.; Ramkhelawon, Bhama; Rayner, Katey J.; Temel, Ryan E.; Perisic, Ljubica; Hedin, Ulf; Maegdefessel, Lars; Garabedian, Michael J.; Holdt, Lesca M.; Teupser, Daniel und Moore, Kathryn J.
(2016):
miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 5: S. 942-951
Himmerich, Hubertus; Wolf, Jörg-Egbert; Zimmermann, Peter; Bühler, Antje H.; Holdt, Lesca M.; Teupser, Daniel; Kirkby, Kenneth C.; Willmund, Gerd D. und Wesemann, Ulrich
(2016):
Serum Concentrations of Tumor Necrosis Factor-α and its Soluble Receptors in Soldiers with and Without Combat-related Posttraumatic Stress Disorder: Influence of Age and Body Mass Index.
In: Chinese Medical Journal, Bd. 129, Nr. 6: S. 751-752
Himmerich, Hubertus; Wesemann, Ulrich; Dalton, Bethan; Holdt, Lesca M.; Teupser, Daniel und Willmund, Gerd D.
(2016):
Exploring an association between hostility and serum concentrations of TNF-alpha and its soluble receptors.
In: Journal of Psychosomatic Research, Bd. 91: S. 87-88
Kolben, Thomas; Hary, Thomas; Holdt, Lesca M.; Schwarz, Theresa M.; Goess, Christine; Wuerstlein, Rachel; Gallwas, Julia; Toth, Bettina; Weissenbacher, Tobias; Jeschke, Udo; Harbeck, Nadia und Ditsch, Nina
(2016):
Thyroid Hormones and Vitamin D in Patients with Breast Cancer with Mutations in BRCA1 or BRCA2 Genes.
In: Anticancer Research, Bd. 36, Nr. 6: S. 3185-3190
Himmerich, Hubertus; Willmund, Gerd D.; Zimmermann, Peter; Wolf, Jörg-Egbert; Bühler, Antje H.; Kirkby, Kenneth C.; Dalton, Bethan; Holdt, Lesca M.; Teupser, Daniel und Wesemann, Ulrich
(2016):
Serum concentrations of TNF-α and its soluble receptors during psychotherapy in German soldiers suffering from combat-related PTSD.
In: Psychiatria Danubina, Bd. 28, Nr. 3: S. 293-298
Schmidt, Frank M.; Weschenfelder, Julia; Sander, Christian; Minkwitz, Juliane; Thormann, Julia; Chittka, Tobias; Mergl, Roland; Kirkby, Kenneth C.; Fasshauer, Mathias; Stumvoll, Michael; Holdt, Lesca M.; Teupser, Daniel; Hegerl, Ulrich und Himmerich, Hubertus
(2015):
Inflammatory Cytokines in General and Central Obesity and Modulating Effects of Physical Activity.
In: PLOS ONE 10(3), e0121971 [PDF, 238kB]
In: PLOS ONE 10(3), e0121971 [PDF, 238kB]
Burkhardt, Ralph; Kirsten, Holger; Beutner, Frank; Holdt, Lesca M.; Gross, Arnd; Teren, Andrej; Toenjes, Anke; Becker, Susen; Krohn, Knut; Kovacs, Peter; Stumvoll, Michael; Teupser, Daniel; Thiery, Joachim; Ceglarek, Uta und Scholz, Markus
(2015):
Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.
In: PLOS Genetics 11(9), e1005510 [PDF, 1MB]
In: PLOS Genetics 11(9), e1005510 [PDF, 1MB]
Tolios, Alexander; Teupser, Daniel und Holdt, Lesca M.
(2015):
Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood.
In: PLOS ONE 10(12), e0143889 [PDF, 2MB]
In: PLOS ONE 10(12), e0143889 [PDF, 2MB]
Hoffmann, Steve; Otto, Christian; Doose, Gero; Tanzer, Andrea; Langenberger, David; Christ, Sabina; Kunz, Manfred; Holdt, Lesca M.; Teupser, Daniel; Hackermüller, Jörg und Stadler, Peter F.
(2014):
A multi-split mapping algorithm for circular RNA, splicing, trans-splicing and fusion detection.
In: Genome Biology
15:R34
[PDF, 645kB]
Grimm, Christian; Holdt, Lesca M.; Chen, Cheng-Chang; Hassan, Sami; Müller, Christoph; Jörs, Simone; Cuny, Hartmut; Kissing, Sandra; Schröder, Bernd; Butz, Elisabeth; Northoff, Bernd; Castonguay, Jan; Luber, Christian A.; Moser, Markus; Spahn, Saskia; Luellmann-Rauch, Renate; Fendel, Christina; Klugbauer, Norbert; Griesbeck, Oliver; Haas, Albert; Mann, Matthias; Bracher, Franz; Teupser, Daniel; Saftig, Paul; Biel, Martin und Wahl-Schott, Christian
(2014):
High susceptibility to fatty liver disease in two-pore channel 2-deficient mice.
In: Nature Communications, Bd. 5, 4699
[PDF, 3MB]
Häntzsch, Madlen; Tolios, Alexander; Beutner, Frank; Nagel, Dorothea; Thiery, Joachim; Teupser, Daniel und Holdt, Lesca M.
(2014):
Comparison of Whole Blood RNA Preservation Tubes and Novel Generation RNA Extraction Kits for Analysis of mRNA and MiRNA Profiles.
In: PLOS ONE 9(12), e113298 [PDF, 1MB]
In: PLOS ONE 9(12), e113298 [PDF, 1MB]
Holdt, Lesca M. und Teupser, Daniel
(Oktober 2013):
From genotype to phenotype in human atherosclerosis - recent findings.
In: Current Opinion in Lipidology, Bd. 24, Nr. 5: S. 410-418
[PDF, 1MB]