|
Eine Ebene nach oben |
Gruppiert nach:
Dokumententyp
| Veröffentlichungsdatum
Springe zu: Zeitschriftenartikel | Buchbeitrag
Anzahl der Publikationen: 48
Zeitschriftenartikel
Janjic, Aleksandar; Wange, Lucas E.; Bagnoli, Johannes W.; Geuder, Johanna; Nguyen, Phong; Richter, Daniel; Vieth, Beate; Vick, Binje; Jeremias, Irmela; Ziegenhain, Christoph; Hellmann, Ines und Enard, Wolfgang
(31. März 2022):
Prime-seq, efficient and powerful bulk RNA sequencing.
In: Genome Biology, Bd. 23
[PDF, 2MB]
Carlet, Michela; Schmelz, Karin; Vergalli, Jenny; Herold, Tobias; Senft, Daniela; Jurinovic, Vindi; Hoffmann, Thomas; Proba, Jutta; Weichert, Nina; Junghanss, Christian; Roth, Mareike; Eschenburg, Georg; Barz, Malwine; Henze, Guenter; Eckert, Cornelia; Eggert, Angelika; Zuber, Johannes; Hundsdoerfer, Patrick und Jeremias, Irmela
(2022):
X-linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL.
In: EMBO Molecular Medicine, Bd. 15, Nr. 1, e14557
Janssen, Maike; Schmidt, Christina; Bruch, Peter-Martin; Blank, Maximilian F.; Rohde, Christian; Waclawiczek, Alexander; Heid, Daniel; Renders, Simon; Goellner, Stefanie; Vierbaum, Lisa; Besenbeck, Birgit; Herbst, Sophie A.; Knoll, Mareike; Kolb, Carolin; Przybylla, Adriana; Weidenauer, Katharina; Ludwig, Anne Kathrin; Fabre, Margarete; Gu, Muxin; Schlenk, Richard F.; Stoelzel, Friedrich; Bornhaeuser, Martin; Roellig, Christoph; Platzbecker, Uwe; Baldus, Claudia; Serve, Hubert; Sauer, Tim; Raffel, Simon; Pabst, Caroline; Vassiliou, George; Vick, Binje; Jeremias, Irmela; Trumpp, Andreas; Krijgsveld, Jeroen; Mueller-Tidow, Carsten und Dietrich, Sascha
(2022):
Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1.
In: Blood, Bd. 140, Nr. 24: S. 2594-2610
Wirth, Anna-Katharina; Wange, Lucas; Vosberg, Sebastian; Henrich, Kai-Oliver; Rausch, Christian; Oezdemir, Erbey; Zeller, Christina M.; Richter, Daniel; Feuchtinger, Tobias; Kaller, Markus; Hermeking, Heiko; Greif, Philipp A.; Senft, Daniela; Jurinovic, Vindi; Bahrami, Ehsan; Jayavelu, Ashok Kumar; Westermann, Frank; Mann, Matthias; Enard, Wolfgang; Herold, Tobias und Jeremias, Irmela
(2022):
In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance.
In: Leukemia, Bd. 36: S. 2863-2874
Koschade, Sebastian E.; Klann, Kevin; Shaid, Shabnam; Vick, Binje; Stratmann, Jan A.; Thölken, Marlyn; Meyer, Laura M.; Duy Nguyen, The; Campe, Julia; Moser, Laura M.; Hock, Susanna; Baker, Fatima; Meyer, Christian T.; Wempe, Frank; Serve, Hubert; Ullrich, Evelyn; Jeremias, Irmela; Muench, Christian und Brandts, Christian H.
(2022):
Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia.
In: Leukemia, Bd. 36, Nr. 10: S. 2396-2407
Philipp, Nora; Kazerani, Maryam; Nicholls, Alyssa; Vick, Binje; Wulf, Jan; Straub, Tobias; Scheurer, Michaela; Muth, Amelie; Hänel, Gerulf; Nixdorf, Daniel; Sponheimer, Monika; Ohlmeyer, Malte; Lacher, Sonja M.; Brauchle, Bettina; Marcinek, Anetta; Rohrbacher, Lisa; Leutbecher, Alexandra; Rejeski, Kai; Weigert, Oliver; Bergwelt-Baildon, Michael von; Theurich, Sebastian; Kischel, Roman; Jeremias, Irmela; Bücklein, Veit und Subklewe, Marion
(2022):
T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals.
In: Blood, Bd. 140, Nr. 10: S. 1104-1118
Zanetti, Samanta Romina; Velasco-Hernandez, Talia; Gutierrez-Aguera, Francisco; Diaz, Victor M.; Romecin, Paola Alejandra; Roca-Ho, Heleia; Sanchez-Martinez, Diego; Tirado, Nestor; Baroni, Matteo Libero; Petazzi, Paolo; Torres-Ruiz, Raul; Molina, Oscar; Bataller, Alex; Fuster, Jose Luis; Ballerini, Paola; Juan, Manel; Jeremias, Irmela; Bueno, Clara und Menendez, Pablo
(2022):
A novel and efficient tandem CD19-and CD22-directed CAR for B cell ALL.
In: Molecular Therapy, Bd. 30, Nr. 2: S. 550-563
Kellner, Markus; Neubeck, Bettina von; Czogalla, Bastian; Feederle, Regina; Vick, Binje; Jeremias, Irmela und Zeidler, Reinhard
(2022):
A Novel Anti-CD73 Antibody That Selectively Inhibits Membrane CD73 Shows Antitumor Activity and Induces Tumor Immune Escape.
In: Biomedicines, Bd. 10, Nr. 4
[PDF, 5MB]
Heinrich, Kathrin; Miller-Phillips, Lisa; Ziemann, Frank; Hasselmann, Korbinian; Rühlmann, Katharina; Flach, Madeleine; Biro, Dorottya; Bergwelt-Baildon, Michael von; Holch, Julian; Herold, Tobias; Baumgarten, Louisa von; Greif, Philip A. 
ORCID: https://orcid.org/0000-0002-3744-7936; Jeremias, Irmela; Wuerstlein, Rachel; Casuscelli, Jozefina; Spitzweg, Christine; Seidensticker, Max; Renz, Bernhard; Corradini, Stefanie; Baumeister, Philipp; Goni, Elisabetta; Tufman, Amanda; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Klauschen, Frederick; Metzeler, Klaus H.; Heinemann, Volker und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2022):
Lessons learned: the first consecutive 1000 patients of the CCCMunich(LMU) Molecular Tumor Board.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 5: S. 1905-1915
[PDF, 728kB]
ORCID: https://orcid.org/0000-0002-3744-7936; Jeremias, Irmela; Wuerstlein, Rachel; Casuscelli, Jozefina; Spitzweg, Christine; Seidensticker, Max; Renz, Bernhard; Corradini, Stefanie; Baumeister, Philipp; Goni, Elisabetta; Tufman, Amanda; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Klauschen, Frederick; Metzeler, Klaus H.; Heinemann, Volker und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2022):
Lessons learned: the first consecutive 1000 patients of the CCCMunich(LMU) Molecular Tumor Board.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 5: S. 1905-1915
[PDF, 728kB]
Zeller, Christina ORCID: https://orcid.org/0000-0003-1834-965X; Richter, Daniel ORCID: https://orcid.org/0000-0003-1302-9083; Jurinovic, Vindi; Valtierra-Gutiérrez, Ilse A. ORCID: https://orcid.org/0000-0003-4128-5914; Jayavelu, Ashok Kumar; Mann, Matthias; Bagnoli, Johannes W. ORCID: https://orcid.org/0000-0003-0393-6157; Hellmann, Ines ORCID: https://orcid.org/0000-0003-0588-1313; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Enard, Wolfgang ORCID: https://orcid.org/0000-0002-4056-0550; Vick, Binje ORCID: https://orcid.org/0000-0003-1956-2778 und Jeremias, Irmela ORCID: https://orcid.org/0000-0003-1773-7677
(2022):
Adverse stem cell clones within a single patient’s tumor predict clinical outcome in AML patients.
In: Journal of Hematology & Oncology, Bd. 15, 25
[PDF, 1MB]
ORCID: https://orcid.org/0000-0003-1834-965X; Richter, Daniel ORCID: https://orcid.org/0000-0003-1302-9083; Jurinovic, Vindi; Valtierra-Gutiérrez, Ilse A. ORCID: https://orcid.org/0000-0003-4128-5914; Jayavelu, Ashok Kumar; Mann, Matthias; Bagnoli, Johannes W. ORCID: https://orcid.org/0000-0003-0393-6157; Hellmann, Ines ORCID: https://orcid.org/0000-0003-0588-1313; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Enard, Wolfgang ORCID: https://orcid.org/0000-0002-4056-0550; Vick, Binje ORCID: https://orcid.org/0000-0003-1956-2778 und Jeremias, Irmela ORCID: https://orcid.org/0000-0003-1773-7677
(2022):
Adverse stem cell clones within a single patient’s tumor predict clinical outcome in AML patients.
In: Journal of Hematology & Oncology, Bd. 15, 25
[PDF, 1MB]
Sanchez-Martinez, Diego; Gutierrez-Aguera, Francisco; Romecin, Paola; Vinyoles, Meritxell; Palomo, Marta; Tirado, Nestor; Romina Zanetti, Samanta; Juan, Manel; Carlet, Michela; Jeremias, Irmela und Menendez, Pablo
(2021):
Enforced sialyl-Lewis-X (sLeX) display in E-selectin ligands by exofucosylation is dispensable for CD19-CAR T-cell activity and bone marrow homing.
In: Clinical and Translational Medicine, Bd. 11, Nr. 2, e280
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. und Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357
(2021):
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of hematology & oncology, Bd. 14, 155
[PDF, 3MB]
ORCID: https://orcid.org/0000-0002-4528-8357
(2021):
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of hematology & oncology, Bd. 14, 155
[PDF, 3MB]
Augsberger, Christian; Hanel, Gerulf; Xu, Wei; Pulko, Vesna; Hanisch, Lydia Jasmin; Augustin, Angelique; Challier, John; Hunt, Katharina; Vick, Binje; Rovatti, Pier Eduardo; Krupka, Christina; Rothe, Maurine; Schonle, Anne; Sam, Johannes; Lezan, Emmanuelle; Ducret, Axel; Ortiz-Franyuti, Daniela; Walz, Antje-Christine; Benz, Jorg; Bujotzek, Alexander; Lichtenegger, Felix S.; Gassner, Christian; Carpy, Alejandro; Lyamichev, Victor; Patel, Jigar; Konstandin, Nikola; Tunger, Antje; Schmitz, Marc; Bergwelt-Baildon, Michael von; Spiekermann, Karsten; Vago, Luca; Jeremias, Irmela; Marrer-Berger, Estelle; Umana, Pablo; Klein, Christian und Subklewe, Marion
(2021):
Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody.
In: Blood, Bd. 138, Nr. 25: S. 2655-2669
Kempf, Julia M.; Weser, Sabrina; Bartoschek, Michael D.; Metzeler, Klaus H.; Vick, Binje; Herold, Tobias; Voelse, Kerstin; Mattes, Raphael; Scholz, Manuela; Wange, Lucas E.; Festini, Moreno; Ugur, Enes; Roas, Maike; Weigert, Oliver; Bultmann, Sebastian; Leonhardt, Heinrich; Schotta, Gunnar; Hiddemann, Wolfgang; Jeremias, Irmela und Spiekermann, Karsten
(2021):
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
In: Scientific Reports, Bd. 11, Nr. 1, 5838
Lenk, Lennart; Carlet, Michela; Vogiatzi, Fotini; Spory, Lea; Winterberg, Dorothee; Cousins, Antony; Vossen-Gajcy, Michaela; Ibruli, Olta; Vokuhl, Christian; Cario, Gunnar; El Ayoubi, Omar; Kramer, Lisa; Ritgen, Matthias; Bruggemann, Monika; Hasler, Robert; Schrappe, Martin; Fuhrmann, Stephan; Halsey, Christina; Jeremias, Irmela; Hobeika, Elias; Jumaa, Hassan; Alsadeq, Ameera und Schewe, Denis M.
(2021):
CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia.
In: Communications Biology, Bd. 4, Nr. 1, 73
Liu, Wen-Hsin; Völse, Kerstin; Senft, Daniela und Jeremias, Irmela
(2021):
A reporter system for enriching CRISPR/Cas9 knockout cells in technically challenging settings like patient models.
In: Scientific Reports, Bd. 11, Nr. 1, 12649
Messner, Martina; Mandl, Melanie M.; Hackl, Mathias W.; Reinhardt, Till; Ardelt, Maximilian A.; Szczepanowska, Karolina; Fraedrich, Julian E.; Waschke, Jens; Jeremias, Irmela; Fux, Anja; Stahl, Matthias; Vollmar, Angelika M.; Sieber, Stephan A. und Pachmayr, Johanna
(2021):
Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers.
In: Scientific Reports, Bd. 11, Nr. 1, 11185
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. und Hopfner, Karl-Peter
(2021):
SIRP alpha-alpha CD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of Hematology & Oncology, Bd. 14, Nr. 1, 155
Yankova, Eliza; Blackaby, Wesley; Albertella, Mark; Rak, Justyna; De Braekeleer, Etienne; Tsagkogeorga, Georgia; Pilka, Ewa S.; Aspris, Demetrios; Leggate, Dan; Hendrick, Alan G.; Webster, Natalie A.; Andrews, Byron; Fosbeary, Richard; Guest, Patrick; Irigoyen, Nerea; Eleftheriou, Maria; Gozdecka, Malgorzata; Dias, Joao M. L.; Bannister, Andrew J.; Vick, Binje; Jeremias, Irmela; Vassiliou, George S.; Rausch, Oliver; Tzelepis, Konstantinos und Kouzarides, Tony
(2021):
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
In: Nature, Bd. 593, Nr. 7860: S. 597-601
Jensen, Patrizia; Carlet, Michela; Schlenk, Richard F.; Weber, Andrea; Kress, Jana; Brunner, Ines; Slabicki, Mikolaj; Grill, Gregor; Weisemann, Simon; Cheng, Ya-Yun; Jeremias, Irmela; Scholl, Claudia und Froehling, Stefan
(2020):
Requirement for LIM kinases in acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 12: S. 3173-3185
Stief, Sophie M.; Hanneforth, Anna-Li; Weser, Sabrina; Mattes, Raphael; Carlet, Michela; Liu, Wen-Hsin; Bartoschek, Michael D.; Moreno, Helena Dominguez; Oettle, Matthias; Kempf, Julia; Vick, Binje; Ksienzyk, Bianka; Tizazu, Belay; Rothenberg-Thurley, Maja; Quentmeier, Hilmar; Hiddemann, Wolfgang; Vosberg, Sebastian; Greif, Philipp A.; Metzeler, Klaus H.; Schotta, Gunnar; Bultmann, Sebastian; Jeremias, Irmela; Leonhardt, Heinrich und Spiekermann, Karsten
(2020):
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 1: S. 50-62
Liu, Wen-Hsin; Mrozek-Gorska, Paulina; Wirth, Anna-Katharina; Herold, Tobias; Schwarzkopf, Larissa; Pich, Dagmar; Voelse, Kerstin; Melo-Narvaez, M. Camila; Carlet, Michela; Hammerschmidt, Wolfgang und Jeremias, Irmela
(2020):
Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL.
In: Biomarker Research, Bd. 8, Nr. 1, 46
Stenger, Dana; Stief, Tanja A.; Kaeuferle, Theresa; Willier, Semjon; Rataj, Felicitas; Schober, Kilian; Vick, Binje; Lotfi, Ramin; Wagner, Beate; Grünewald, Thomas G. P.; Kobold, Sebastian; Busch, Dirk H.; Jeremias, Irmela; Blaeschke, Franziska und Feuchtinger, Tobias
(2020):
Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR.
In: Blood, Bd. 136, Nr. 12: S. 1407-1418
Becker, Martin; Noll-Puchta, Heidi; Amend, Diana; Nolte, Florian; Fuchs, Christiane; Jeremias, Irmela und Braun, Christian J.
(2020):
CLUE: a bioinformatic and wet-lab pipeline for multiplexed cloning of custom sgRNA libraries.
In: Nucleic Acids Research, Bd. 48, Nr. 13, e78
Bamezai, Shiva; Demir, Deniz; Pulikkottil, Alex Jose; Ciccarone, Fabio; Fischbein, Elena; Sinha, Amit; Borga, Chiara; te Kronnie, Geertruy; Meyer, Lueder-Hinrich; Mohr, Fabian; Goetze, Maria; Caiafa, Paola; Debatin, Klaus-Michael; Doehner, Konstanze; Doehner, Hartmut; Gonzalez-Menendez, Irene; Quintanilla-Fend, Leticia; Herold, Tobias; Jeremias, Irmela; Feuring-Buske, Michaela; Buske, Christian und Rawat, Vijay P. S.
(2020):
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition.
In: Leukemia, Bd. 35, Nr. 2: S. 389-403
Ruzicka, Michael; König, Lars M.; Formisano, Simone; Boehmer, Daniel F. R.; Vick, Binje; Heuer, Eva-M.; Meinl, Hanna; Kocheise, Lorenz; Zeitlhoefler, Marcus; Ahlfeld, Julia; Kobold, Sebastian; Endres, Stefan; Subklewe, Marion; Duewell, Peter; Schnurr, Max; Jeremias, Irmela; Lichtenegger, Felix S. und Rothenfusser, Simon
(2020):
RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade.
In: Leukemia, Bd. 34, Nr. 4: S. 1017-1026
Salik, Basit; Yi, Hangyu; Hassan, Nunki; Santiappillai, Nancy; Vick, Binje; Connerty, Patrick; Duly, Alastair; Trahair, Toby; Woo, Andrew J.; Beck, Dominik; Liu, Tao; Spiekermann, Karsten; Jeremias, Irmela; Wang, Jianlong; Kavallaris, Maria; Haber, Michelle; Norris, Murray D.; Liebermann, Dan A.; D'Andrea, Richard J.; Murriel, Christopher und Wang, Jenny Y.
(2020):
Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia.
In: Cancer Cell, Bd. 38, Nr. 2: S. 263-278
Redondo Monte, Enric; Wilding, Anja; Leubolt, Georg; Kerbs, Paul; Bagnoli, Johannes W.; Hartmann, Luise; Hiddemann, Wolfgang; Chen-Wichmann, Linping; Krebs, Stefan; Blum, Helmut; Cusan, Monica; Vick, Binje; Jeremias, Irmela; Enard, Wolfgang; Theurich, Sebastian; Wichmann, Christian und Greif, Philipp A.
(2020):
ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells.
In: Oncogene, Bd. 39: S. 3195-3205
[PDF, 1MB]
Koczian, Fabian; Naglo, Olga; Vomacka, Jan; Vick, Binje; Servatius, Phil; Zisis, Themistoklis; Hettich, Britta; Kazmaier, Uli; Sieber, Stephan A.; Jeremias, Irmela; Zahler, Stefan und Braig, Simone
(2019):
Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics.
In: Haematologica, Bd. 104, Nr. 3: S. 546-555
Senft, Daniela und Jeremias, Irmela
(2019):
A rare subgroup of leukemia stem cells harbors relapse-inducing potential in acute lymphoblastic leukemia.
In: Experimental Hematology, Bd. 69: S. 1-10
Lynch, Jennifer R.; Salik, Basit; Connerty, Patrick; Vick, Binje; Leung, Halina; Pijning, Aster; Jeremias, Irmela; Spiekermann, Karsten; Trahair, Toby; Liu, Tao; Haber, Michelle; Norris, Murray D.; Woo, Andrew J.; Hogg, Philip; Wang, Jianlong und Wang, Jenny Y.
(2019):
JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis.
In: Leukemia, Bd. 33, Nr. 6: S. 1400-1410
Gaiser, Ann-Kathrin; Hafner, Susanne; Schmiech, Michael; Buchele, Berthold; Schafer, Patrick; Arnim, Christine A. von; Calzia, Enrico; Feuring-Buske, Michaela; Buske, Christian; Vick, Binje; Jeremias, Irmela; Syrovets, Tatiana und Simmet, Thomas
(2019):
Gold Nanoparticles with Selective Antileukemic Activity In Vitro and In Vivo Target Mitochondrial Respiration.
In: Advanced Therapeutics, Bd. 2, Nr. 6, UNSP 1800149
Pan, Chenchen; Schoppe, Oliver; Parra-Damas, Arnaldo; Cai, Ruiyao; Todorov, Mihail Ivilinov; Gondi, Gabor; Neubeck, Bettina von; Boeguercue-Seidel, Nuray; Seidel, Sascha; Sleiman, Katia; Veltkamp, Christian; Foerstera, Benjamin; Mai, Hongcheng; Rong, Zhouyi; Trompak, Omelyan; Ghasemigharagoz, Alireza; Reimer, Madita Alice; Cuesta, Angel M.; Coronel, Javier; Jeremias, Irmela; Saur, Dieter; Acker-Palmer, Amparo; Acker, Till; Garvalov, Boyan K.; Menze, Björn; Zeidler, Reinhard und Ertuerk, Ali
(2019):
Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.
In: Cell, Bd. 179, Nr. 7
Kirsch, Volker C.; Orgler, Christina; Braig, Simone; Jeremias, Irmela; Auerbach, David; Müller, Rolf; Vollmar, Angelika M. und Sieber, Stephan A.
(2019):
The Cytotoxic Natural Product Vioprolide A Targets Nucleolar Protein 14, which is Essential for Ribosome Biogenesis.
In: Angewandte Chemie-International Edition, Bd. 59, Nr. 4: S. 1595-1600
Sarrach, Sannia; Huang, Yuanchi; Niedermeyer, Sebastian; Hachmeister, Matthias; Fischer, Laura; Gille, Sebastian; Pan, Min; Mack, Brigitte; Kranz, Gisela; Libl, Darko; Merl-Pham, Juliane; Hauck, Stefanie M.; Tomada, Elisa Paoluzzi; Kieslinger, Matthias; Jeremias, Irmela; Scialdone, Antonio und Gires, Olivier
(2018):
Spatiotemporal patterning of EpCAM is important for murine embryonic endo- and mesodermal differentiation.
In: Scientific Reports, Bd. 8, 1801
[PDF, 9MB]
Tzelepis, Konstantinos; De Braekeleer, Etienne; Aspris, Demetrios; Barbieri, Isaia; Vijayabaskar, M. S.; Liu, Wen-Hsin; Gozdecka, Malgorzata; Metzakopian, Emmanouil; Toop, Hamish D.; Dudek, Monika; Robson, Samuel C.; Hermida-Prado, Francisco; Yang, Yu Hsuen; Babaei-Jadidi, Roya; Garyfallos, Dimitrios A.; Ponstingl, Hannes; Dias, Joao M. L.; Gallipoli, Paolo; Seiler, Michael; Buonamici, Silvia; Vick, Binje; Bannister, Andrew J.; Rad, Roland; Prinjha, Rab K.; Marioni, John C.; Huntly, Brian; Batson, Jennifer; Morris, Jonathan C.; Pina, Cristina; Bradley, Allan; Jeremias, Irmela; Bates, David O.; Yusa, Kosuke; Kouzarides, Tony und Vassiliou, George S.
(2018):
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.
In: Nature Communications, Bd. 9, 5378
[PDF, 2MB]
Göllner, Stefanie; öllerich, Thomas; Agrawal-Singh, Shuchi; Schenk, Tino; Klein, Hans-Ulrich; Rohde, Christian; Pabst, Caroline; Sauer, Tim; Lerdrup, Mads; Tavor, Sigal; Stölzel, Friedrich; Herold, Sylvia; Ehninger, Gerhard; Köhler, Gabriele; Pan, Kuan-Ting; Urlaub, Henning; Serve, Hubert; Dugas, Martin; Spiekermann, Karsten; Vick, Binje; Jeremias, Irmela; Berdel, Wolfgang E.; Hansen, Klaus; Zelent, Arthur; Wickenhauser, Claudia; Müller, Lutz P.; Thiede, Christian und Müller-Tidow, Carsten
(2017):
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.
In: Nature Medicine, Bd. 23, Nr. 1: S. 69-78
Finkenzeller, Cornelia; Carlet, Michela; Vosberg, Sebastian; Neumann, Martin; Riecken, Kristoffer; Cornils, Kerstin; Fehse, Boris; Baldus, Claudia D.; Greif, Philipp A. und Jeremias, Irmela
(2017):
Clones with and without Sensitivity towards Treatment in Vivo Co-Exist within a Single Sample of a Patient with ALL.
In: Annals of Hematology, Bd. 96:
S75-S75
Kläger, Susan; Heinzlmeir, Stephanie; Wilhelm, Mathias; Polzer, Harald; Vick, Binje; König, Paul-Albert; Reinecke, Maria; Ruprecht, Benjamin; Petzoldt, Svenja; Meng, Chen; Zecha, Jana; Reiter, Katrin; Qiao, Huichao; Helm, Dominic; Koch, Heiner; Schoof, Melanie; Canevari, Giulia; Casale, Elena; Depaolini, Stefania Re; Feuchtinger, Annette; Wu, Zhixiang; Schmidt, Tobias; Rückert, Lars; Becker, Wilhelm; Hünges, Jan; Garz, Anne-Kathrin; Gohlke, Björn-Oliver; Zolg, Daniel Paul; Kayser, Gian; Vooder, Tonu; Preissner, Robert; Hahne, Hannes; Tonisson, Neeme; Kramer, Karl; Götze, Katharina; Bassermann, Florian; Schlegl, Judith; Ehrlich, Hans-Christian; Aiche, Stephan; Walch, Axel; Greif, Philipp A.; Schneider, Sabine; Felder, Eduard Rudolf; Ruland, Jürgen; Medard, Guillaume; Jeremias, Irmela; Spiekermann, Karsten und Kuster, Bernhard
(2017):
The target landscape of clinical kinase drugs.
In: Science, Bd. 358, Nr. 6367, eaan4368
Ebinger, Sarah; Özdemir, Erbey Ziya; Ziegenhain, Christoph; Tiedt, Sebastian; Castro Alves, Catarina; Grunert, Michaela; Dworzak, Michael; Lutz, Christoph; Turati, Virginia A.; Enver, Tariq; Horny, Hans-Peter; Sotlar, Karl; Parekh, Swati; Spiekermann, Karsten; Hiddemann, Wolfgang; Schepers, Aloys; Polzer, Bernhard; Kirsch, Stefan; Hoffmann, Martin; Knapp, Bettina; Hasenauer, Jan; Pfeifer, Heike; Panzer-Grümayer, Renate; Enard, Wolfgang; Gires, Olivier und Jeremias, Irmela
(2016):
Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia.
In: Cancer Cell, Bd. 30, Nr. 6: S. 849-862
Vergalli, Jenny; Carlet, Michela; Vergalli, Jenny; Hoffmann, Thomas; Roth, Mareike; Zuber, Johannes und Jeremias, Irmela
(2016):
Novel genetically engineered patient-derived xenograft (GEPDX) models reveal that XIAP plays an essential role for patients’ all growing in mice.
In: Experimental Hematology, Bd. 44, Nr. 9:
S105-S105
Krupka, Christina; Kufer, Peter; Kischel, Roman; Zugmaier, Gerhard; Köhnke, Thomas; Lichtenegger, Felix; Altmann, Torben; Spiekermann, Karsten; Vick, Binje; Jeremias, Irmela; Hiddemann, Wolfgang; Riethmüller, Gert und Subklewe, Marion
(2016):
Characterization of covariables modulating CD33/CD3 BITE antibody construct mediated cytotoxicity against primary AML cells.
In: Cancer Immunology Research, Bd. 4, Nr. 1
Townsend, Elizabeth C.; Murakami, Mark A.; Christodoulou, Alexandra; Christie, Amanda L.; Köster, Johannes; DeSouza, Tiffany A.; Morgan, Elizabeth A.; Kallgren, Scott P.; Liu, Huiyun; Wu, Shuo-Chieh; Plana, Olivia; Montero, Joan; Stevenson, Kristen E.; Rao, Prakash; Vadhi, Raga; Andreeff, Michael; Armand, Philippe; Ballen, Karen K.; Barzaghi-Rinaudo, Patrizia; Cahill, Sarah; Clark, Rachael A.; Cooke, Vesselina G.; Davids, Matthew S.; DeAngelo, Daniel J.; Dorfman, David M.; Eaton, Hilary; Ebert, Benjamin L.; Etchin, Julia; Firestone, Brant; Fisher, David C.; Freedman, Arnold S.; Galinsky, Ilene A.; Gao, Hui; Garcia, Jacqueline S.; Garnache-Ottou, Francine; Graubert, Timothy A.; Gutierrez, Alejandro; Halilovic, Ensar; Harris, Marian H.; Herbert, Zachary T.; Horwitz, Steven M.; Inghirami, Giorgio; Intlekoffer, Andrew M.; Ito, Moriko; Izraeli, Shai; Jacobsen, Eric D.; Jacobson, Caron A.; Jeay, Sebastien; Jeremias, Irmela; Kelliher, Michelle A.; Koch, Raphael; Konopleva, Marina; Kopp, Nadja; Kornblau, Steven M.; Kung, Andrew L.; Kupper, Thomas S.; LaBoeuf, Nicole; LaCasce, Ann S.; Lees, Emma; Li, Loretta S.; Look, A. Thomas; Murakami, Masato; Muschen, Markus; Neuberg, Donna; Ng, Samuel Y.; Odejide, Oreofe O.; Orkin, Stuart H.; Paquette, Rachel R.; Place, Andrew E.; Roderick, Justine E.; Ryan, Jeremy A.; Sallan, Stephen E.; Shoji, Brent; Silverman, Lewis B.; Soiffer, Robert J.; Steensma, David P.; Stegmaier, Kimberly; Stone, Richard M.; Tamburini, Jerome; Thorner, Aaron R.; Hummelen, Paul van; Wadleigh, Martha; Wiesmann, Marion; Weng, Andrew P.; Wuerthner, Jens U.; Williams, David A.; Wollison, Bruce M.; Lane, Andrew A.; Letai, Anthony; Bertagnolli, Monica M.; Ritz, Jerome; Brown, Myles; Long, Henry; Aster, Jon C.; Shipp, Margaret A.; Griffin, James D. und Weinstock, David M.
(2016):
The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.
In: Cancer Cell, Bd. 29, Nr. 4: S. 574-586
Vick, Binje; Rothenberg, Maja; Sandhöfer, Nadine; Carlet, Michela; Finkenzeller, Cornelia; Krupka, Christina; Grunert, Michaela; Trumpp, Andreas; Corbacioglu, Selim; Ebinger, Martin; André, Maya C.; Hiddemann, Wolfgang; Schneider, Stephanie; Subklewe, Marion; Metzeler, Klaus H.; Spiekermann, Karsten und Jeremias, Irmela
(2015):
An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging.
In: PLOS ONE 10(3), e0120925 [PDF, 3MB]
In: PLOS ONE 10(3), e0120925 [PDF, 3MB]
Wachter, Franziska; Grunert, Michaela; Blaj, Cristina; Weinstock, David M.; Jeremias, Irmela und Ehrhardt, Harald
(2013):
Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling.
In: Cell Communication and Signaling
11:27
[PDF, 443kB]
Terziyska, Nadia; Castro Alves, Catarina; Groiss, Volker; Schneider, Katja; Farkasova, Katarina; Ogris, Manfred; Wagner, Ernst; Ehrhardt, Harald; Brentjens, Renier J.; zur Stadt, Udo; Horstmann, Martin; Quintanilla-Martinez, Leticia und Jeremias, Irmela
(2012):
In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.
In: PLOS ONE 7(12), e52798 [PDF, 1MB]
In: PLOS ONE 7(12), e52798 [PDF, 1MB]
Hoefig, Ines; Ehrhardt, Harald und Jeremias, Irmela
(2012):
Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice.
In: Cell Communication and Signaling
10:8
[PDF, 1MB]
Buchbeitrag
Jeremias, Irmela und Schewe, Denis M.
(2018):
Characteristics and Therapeutic Targeting of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia.
In:
Springer. S. 127-139