Article

Shir, Alexei and Ogris, Manfred and Wagner, Ernst and Levitzki, Alexander (2066): EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice. In: PLOS MEDICINE, Vol. 3, No. 1: pp. 125-135

Maier, Kevin and Martin, Irene and Wagner, Ernst (2012): Sequence Defined Disulfide-Linked Shuttle for Strongly Enhanced Intracellular Protein Delivery. In: Molecular pharmaceutics, Vol. 9, No. 12: pp. 3560-3568

Maier, Kevin and Wagner, Ernst (2012): Acid-Labile Traceless Click Linker for Protein Transduction. In: Journal of the American Chemical Society, Vol. 134, No. 24: pp. 10169-10173

Schaffert, David and Troiber, Christina and Wagner, Ernst (2012): New Sequence-Defined Polyaminoamides with Tailored Endosomolytic Properties for Plasmid DNA Delivery. In: Bioconjugate chemistry, Vol. 23, No. 6: pp. 1157-1165

Dohmen, Christian and Edinger, Daniel and Fröhlich, Thomas and Schreiner, Laura and Lächelt, Ulrich and Troiber, Christina and Rädler, Joachim O. and Hadwiger, Philipp and Vornlocher, Hans-Peter and Wagner, Ernst (2012): Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery. In: ACS nano, Vol. 6, No. 6: pp. 5198-5208

Terziyska, Nadia and Castro Alves, Catarina and Groiss, Volker and Schneider, Katja and Farkasova, Katarina and Ogris, Manfred and Wagner, Ernst and Ehrhardt, Harald and Brentjens, Renier J. and zur Stadt, Udo and Horstmann, Martin and Quintanilla-Martinez, Leticia and Jeremias, Irmela (2012): In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. In: PloS one, Vol. 7, No. 12: e52798

Kopp, Florian and Oak, Prajakta S. and Wagner, Ernst and Roidl, Andreas (2012): miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. In: PloS one, Vol. 7, No. 11: e50469

Wagner, Ernst (2011): Polymers for siRNA Delivery. Inspired by Viruses to be Targeted, Dynamic, and Precise. In: Accounts of chemical research, Vol. 45, No. 7: pp. 1005-1013

Troiber, Christina and Wagner, Ernst (2011): Nucleic Acid Carriers Based on Precise Polymer Conjugates. In: Bioconjugate chemistry, Vol. 22, No. 9: pp. 1737-1752

Yu, Haijun and Nie, Yu and Dohmen, Christian and Li, Yunqiu and Wagner, Ernst (2011): Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry. In: iomacromolecules, Vol. 12, No. 6: pp. 2039-2047

Schaffert, David and Badgujar, Naresh and Wagner, Ernst (2011): Novel Fmoc-Polyamino Acids for Solid-Phase Synthesis of Defined Polyamidoamines. In: Organic letters, Vol. 13, No. 7: pp. 1586-1589

Zintchenko, Arkadi and Philipp, Alexander and Dehshahri, Ali and Wagner, Ernst (2008): Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity. In: Bioconjugate chemistry, Vol. 19, No. 7: pp. 1448-1455

Meyer, Martin and Philipp, Alexander and Oskuee, Reza and Schmidt, Claudia and Wagner, Ernst (2008): Breathing Life into Polycations. Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA Delivery. In: Journal of the American Chemical Society, Vol. 130, No. 11: pp. 3272-3273

Curiel, Tyler J. and Cook, Deborah R. and Bogedain, Christoph and Jilg, Wolfgang and Harrison, Gail S. and Cotten, Matt and Curiel, David T. and Wagner, Ernst (1994): Efficient Foreign Gene Expression in Epstein-Barr Virus-Transformed Human B-Cells. In: Virology, Vol. 198, No. 2: pp. 577-585

Noe, Christian R. and Knollmüller, Max and Miculka, Christian and Dungler, Karin and Wagner, Ernst and Ettmayer, Peter (1994): Chirale Lactole, XI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler Alkanole. In: Chemische Berichte, Vol. 127, No. 5: pp. 887-892

Zatloukal, Kurt and Cotten, Matt and Berger, Manfred and Schmidt, Walter and Wagner, Ernst and Birnstiel, Max L. (1994): In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery. In: Proceedings of the National Academy of Science of the U S A, Vol. 91, No. 11: pp. 5148-5152

Plank, Christian and Oberhauser, Berndt and Mechtler, Karl and Koch, Christian and Wagner, Ernst (1994): The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. In: Journal of Biological Chemistry, Vol. 269: pp. 12918-12924

Cheng, Qi and Cant, Charles and Moll, Thomas and Hofer-Warbinek, Renate and Wagner, Ernst and Birnstiel, Max L. and Bach, Fritz H. and Martin, Rainer de (1994): NK-kappa B subunit-specific regulation of the I kappa B alpha promoter. In: Journal of Biological Chemistry, Vol. 269: pp. 13551-13557

Wagner, Ernst and Curiel, David T. and Cotten, Matt (1994): Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. In: Advanced Drug Delivery Reviews, Vol. 14, No. 1: pp. 113-135

Thurnher, Martin and Wagner, Ernst and Clausen, Henrik and Mechtler, Karl and Rusconi, Sandro and Dinter, André and Birnstiel, Max L. and Berger, Eric G. and Cotten, Matt (1994): Carbohydrate receptor-mediated gene transfer to human T leukaemic cells. In: Glycobiology, Vol. 4: pp. 429-435

Cotten, Matt and Baker, A. and Saltik, Mediyha and Wagner, Ernst and Buschle, M. (1994): Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary cells in the presence of adenovirus. In: Gene Therapy, Vol. 1: pp. 239-246

Zelphati, Olivier and Wagner, Ernst and Leserman, Lee (1994): Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes. In: Antiviral Research, Vol. 25, No. 1: pp. 13-25

Batra, R. K. and Wang-Johanning, F. and Wagner, Ernst and Garver, R. I. and Curiel, David T. (1994): Receptor-mediated gene delivery employing lectin-binding specificity. In: Gene Therapy, Vol. 1: pp. 255-260

Cotten, Matt and Saltik, Mediyha and Kursa, Malgorzata and Wagner, Ernst and Maass, Gerd and Birnstiel, Max L. (1994): Psoralen Treatment of Adenovirus Particles Eliminates Virus Replication and Transcription While Maintaining the Endosomolytic Activity of the Virus Capsid. In: Virology, Vol. 205, No. 1: pp. 254-261

Frank, Sasa and Krasznai, Krisztina and Durovic, Srdan and Lobentanz, Eva-Maria and Dieplinger, Hans and Wagner, Ernst and Zatloukal, Kurt and Cotten, Matt and Utermann, Gerd and Kostner, Gerd M. and Zechner, Rudolf (1994): High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection". The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein. In: Biochemistry, Vol. 33, No. 40: pp. 12329-12339

Zatloukal, Kurt and Schneeberger, A. and Berger, M. and Koszik, F. and Schmidt, Walter and Wagner, Ernst and Cotten, Matt and Buschle, M. and Maass, Gerd and Stingl, Georg and Birnstiel, Max L. (1994): Genetic modification of cells by receptor-mediated adenovirus-augmented gene delivery. A new approach for immunotherapy of cancer. In: Verhandlungen der Deutschen Gesellschaft für Pathologie, Vol. 78: pp. 171-176

Cook, Deborah R. and Maxwell, I. H. and Glode, L. M. and Maxwell, F. and Stevens, J. O. and Purner, M. B. and Wagner, Ernst and Curiel, David T. and Curiel, Tyler J. (1994): Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate. In: Cancer Biotherapy, Vol. 9: pp. 131-141

Cotten, Matt and Wagner, Ernst and Birnstiel, Max L. (1993): Receptor mediated transport of DNA into eukariotic cells. In: Methods in Enzymology, Vol. 217: pp. 618-644

Gao, L. and Wagner, Ernst and Cotten, Matt and Agarwal, Santosh and Harris, C. E. and Romer, M. and Miller, L. and Hu, P.-C. and Curiel, David T. (1993): Direct in vivo gene transfer to the airway epithelium employing adenovirus-polylysine-DNA complexes. In: Human Gene Therapy, Vol. 4: pp. 17-24

Michael, S. I. and Huang, C. H. and Romer, M. and Wagner, Ernst and Hu, P.-C. and Curiel, David T. (1993): Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway. In: Journal of Biological Chemistry, Vol. 268: pp. 6866-6869

Cotten, Matt and Wagner, Ernst and Zatloukal, Kurt and Birnstiel, Max L. (1993): Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants. In: Journal of Virology, Vol. 67, No. 7: pp. 3777-3785

Cotten, Matt and Wagner, Ernst (1993): Non-viral approaches to gene therapy. In: Current Opinion in Biotechnology, Vol. 4, No. 6: pp. 705-710

Zatloukal, Kurt and Schmidt, Walter and Cotten, Matt and Wagner, Ernst and Stingl, Georg and Birnstiel, Max L. (1993): Somatic gene therapy for cancer. The utility of transferrinfection in generating ‘tumor vaccines’. In: Gene, Vol. 135, No. 1-2: pp. 199-207

Harris, C. E. and Agarwal, Santosh and Hu, P.-C. and Wagner, Ernst and Curiel, David T. (1993): Receptor-mediated gene transfer to airway epithelial cells in primary culture. In: American journal of respiratory cell and molecular biology, Vol. 9: pp. 441-447

Plank, Christian and Zatloukal, Kurt and Cotten, Matt and Mechtler, Karl and Wagner, Ernst (1992): Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand. In: Bioconjugate Chemistry, Vol. 3, No. 6: pp. 533-539

Oberhauser, Berndt and Wagner, Ernst (1992): Effective incorporation of 2'-O-methyl-oligoribonucleotides into liposomes and enhanced cell association through modification with thiocholesterol. In: Nucleic Acids Resarch, Vol. 20: pp. 533-538

Curiel, David T. and Wagner, Ernst and Cotten, Matt and Birnstiel, Max L. and Agarwal, Santosh and Li, C.-M. and Loechel, S. and Hu, P.-C. (1992): High-efficiency gene transfer by adenovirus coupled to DNA-polylysine complexes. In: Human Gene Therapy, Vol. 3, No. 2: pp. 147-154

Wagner, Ernst and Zatloukal, Kurt and Cotten, Matt and Kirlappos, Helen and Mechtler, Karl and Curiel, David T. and Birnstiel, Max L. (1992): Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. In: Proceedings of the National Academy of Science of the U S A, Vol. 89, No. 13: pp. 6099-6103

Curiel, David T. and Agarwal, Santosh and Romer, N. and Wagner, Ernst and Cotten, Matt and Birnstiel, Max L. and Boucher, R. C. (1992): Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway. In: American Journal of Respiratory Cell and Molecular Biology, Vol. 6: pp. 247-252

Cotten, Matt and Wagner, Ernst and Zatloukal, Kurt and Phillips, Stephen and Curiel, David T. and Birnstiel, Max L. (1992): High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. In: Proceedings of the National Academy of Science of the U S A, Vol. 89, No. 13: pp. 6094-6098

Wagner, Ernst and Plank, Christian and Zatloukal, Kurt and Cotten, Matt and Birnstiel, Max L. (1992): Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes. Toward a synthetic virus-like gene-transfer vehicle. In: Proceedings of the National Academy of Science of the U S A, Vol. 89, No. 17: pp. 7934-7938

Zatloukal, Kurt and Wagner, Ernst and Cotten, Matt and Phillips, Stephen and Plank, Christian and Steinlein, Peter and Curiel, David T. and Birnstiel, Max L. (1992): Transferrinfection. A Highly Efficient Way to Express Gene Constructs in Eukaryotic Cells. In: Annals of the New York Academy of Sciences, Vol. 660, No. 1: pp. 136-153

Wagner, Ernst and Cotten, Matt and Foisner, Roland and Birnstiel, Max L. (1991): Transferrin-polycation-DNA complexes. The effect of polycations on the structure of the complex and DNA delivery to cells. In: Proceedings of the National Academy of Science of the U S A, Vol. 88, No. 10: pp. 4255-4259

Curiel, David T. and Agarwal, Santosh and Wagner, Ernst and Cotten, Matt (1991): Adenovirus enhancement of transferrin-polylysine-mediated gene delivery. In: Proceedings of the National Academy of Science of the U S A, Vol. 88, No. 19: pp. 8850-8854

Wagner, Ernst and Cotten, Matt and Mechtler, Karl and Kirlappos, Helen and Birnstiel, Max L. (1991): DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety. In: Bioconjugate Chemistry, Vol. 2, No. 4: pp. 226-231

Cotten, Matt and Oberhauser, Berndt and Brunar, Helmut and Holzner, Armin and Issakides, Georg and Noe, Christian R. and Schaffner, Gotthold and Wagner, Ernst and Birnstiel, Max L. (1991): 2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event. In: Nucleic Acids Research, Vol. 19: pp. 2629-2635

Wagner, Ernst and Oberhauser, Berndt and Holzner, Armin and Brunar, Helmut and Issakides, Georg and Schaffner, Gotthold and Cotten, Matt and Knollmüller, Max and Noe, Christian R. (1991): A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites. In: Nucleic Acids Research, Vol. 19: pp. 5965-5971

Noe, Christian R. and Knollmüller, Max and Steinbauer, Gerhard and Wagner, Ernst and Kürner, H. and Ettmayer, Peter and Völlenkle, Horst (1991): Eine einfache Methode zur Steuerung der Reduktion von α-Alkoxy-carbonylverbindungen. In: Monatshefte für Chemie / Chemical Monthly, Vol. 122, No. 4: pp. 299-317

Wagner, Ernst and Xiang, Yi-Bin and Baumann, Karl and Gück, Jürgen and Eschenmoser, Albert (1990): Chemie von alpha-Aminonitrilen. Aziridin-2-carbonitril, ein Vorläufer von rca-O3-Phosphoserinnitril und Glycolaldehyd-phosphat. In: Helvetica Chimica Acta, Vol. 73, No. 5: pp. 1391-1409

Müller, Daniel and Pitsch, Stefan and Kittaka, Atsushi and Wagner, Ernst and Wintner, Claude E. and Eschenmoser, Albert (1990): Chemie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die Reaktionshauptprodukte. In: Helvetica Chimica Acta, Vol. 73, No. 5: pp. 1410-1468

Wagner, Ernst and Zenke, Martin and Cotten, Matt and Beug, Hartmut and Birnstiel, Max L. (1990): Transferrin-polycation conjugates as carriers for DNA uptake into cells. In: Proceedings of the National Academy of Science of the U S A, Vol. 87, No. 9: pp. 3410-3414

Zenke, Martin and Steinlein, Peter and Wagner, Ernst and Cotten, Matt and Beug, Hartmut and Birnstiel, Max L. (1990): Receptor-mediated endocytosis of transferrin-polycation conjugates. An efficient way to introduce DNA into hematopoietic cells. In: Proceedings of the National Academy of Science of the U S A, Vol. 87, No. 10: pp. 3655-3659

Cotten, Matt and Längle-Rouault, Francoise and Kirlappos, Helen and Wagner, Ernst and Mechtler, Karl and Zenke, Martin and Beug, Hartmut and Birnstiel, Max L. (1990): Transferrin-polycation-mediated introduction of DNA into human leukemic cells. Stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels. In: Proceedings of the National Academy of Science of the U S A, Vol. 87, No. 11: pp. 4033-4037

Noe, Christian R. and Knollmüller, Max and Oberhauser, Berndt and Steinbauer, Gerhard and Wagner, Ernst (1986): Chirale Lactole, VI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler alpha-hydroxysubstituierter Nitrile, Alkine und Aldehyde. In: Chemische Berichte, Vol. 119, No. 2: pp. 729-743

Noe, Christian R. and Knollmüller, Max and Wagner, Ernst (1986): Ein einfaches Verfahren zur Herstellung anellierter Thiophene. In: Monatshefte für Chemie / Chemical Monthly, Vol. 117, No. 5: pp. 621-629

Noe, Christian R. and Knollmüller, Max and Wagner, Ernst and Völlenkle, Horst (1985): Chirale Lactole, IV. Selektivitäten bei Acetalisierungsreaktionen enantiomerenreiner Lactole am Beispiel von Octahydro-8,9,9-trimethyl-5,8-methano-2H-1-benzopyran-2-ol. In: Chemische Berichte, Vol. 118, No. 5: pp. 1733-1745

Noe, Christian R. and Knollmüller, Max and Wagner, Ernst and Völlenkle, Horst (1985): Kohlenhydrat-Modelle, I. Kinetische und thermodynamische Effekte bei Acetalisierungsreaktionen enantiomerenreiner Thiolactole. In: Chemische Berichte, Vol. 118, No. 8: pp. 3299-3310

Book Section

Wagner, Ernst and Cotten, Matt and Plank, Christian and Mechtler, Karl and Zatloukal, Kurt and Birnstiel, Max L. (1994): Receptor-mediated gene delivery into mammalian cells. In: Spier, R. E. (ed.) , Animal cell technology: Products of today, prospects for tomorrow. Oxford: Butterworth Heinemann. pp. 30-34

Maass, Gerd and Zatloukal, Kurt and Schmidt, Walter and Berger, M. and Cotten, Matt and Wagner, Ernst and Birnstiel, Max L. and Buschle, M. (1994): The generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells. In: Skouteris, George G. (ed.) , Liver carcinogenesis. Berlin u.a.: Springer. pp. 467-479

Wagner, Ernst (1993): Gentherapie. Neue Wege in der Krebsbehandlung. In: Gerbel, K. (ed.) , Genetische Kunst - Künstliches Leben. Wien: PVS Verleger. pp. 151-154

Conference or Workshop Item

Wagner, Ernst and Buschle, M. and Cotten, Matt and Plank, Christian and Zauner, W. and Birnstiel, Max L. (1994): Synthetic virus-like gene delivery systems. 21. International Symposium on controlled release of bioactive materials, 27-30 Juni 1994, Nizza.