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Anzahl der Publikationen: 89
Zeitschriftenartikel
Burgers, Luisa D.; Li, Yanfen; Michalakis, Stylianos; Ciurus, Sarah; Zahler, Stefan; Mueller, Rolf und Fuerst, Robert
(2022):
The protein biosynthesis inhibitor vioprolide A evokes anti-angiogenic and pro-survival actions by targeting NOP14 and decreasing VEGF receptor 2and TAZ-signaling.
In: Biomedicine & Pharmacotherapy, Bd. 152, 113174
Zisis, Themistoklis; Brueckner, David B.; Brandstaetter, Tom; Siow, Wei Xiong; d'Alessandro, Joseph; Vollmar, Angelika M.; Broedersz, Chase P. und Zahler, Stefan
(2022):
Disentangling cadherin-mediated cell-cell interactions in collective cancer cell migration.
In: Biophysical Journal, Bd. 121, Nr. 1: S. 44-60
Wang, Pengyu; Klassmueller, Thomas; Karg, Cornelia A.; Kretschmer, Maibritt; Zahler, Stefan; Braig, Simone; Bracher, Franz; Vollmar, Angelika M. und Moser, Simone
(2022):
Using the yeast three-hybrid system for the identification of small molecule-protein interactions with the example of ethinylestradiol.
In: Biological Chemistry, Bd. 403, Nr. 4: S. 421-431
Deiringer, Natalie; Ruediger, Daniel; Luxbacher, Thomas; Zahler, Stefan und Friess, Wolfgang
(2022):
Catching Speedy Gonzales: Driving forces for Protein Film Formation on Silicone Rubber Tubing During Pumping.
In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 6: S. 1577-1586
Illes, Bernhard; Fuchs, Adrian; Gegenfurtner, Florian; Plötz, Evelyn; Zahler, Stefan; Vollmar, Angelika M. und Engelke, Hanna
(2021):
Spatio-selective activation of nuclear translocation of YAP with light directs invasion of cancer cell spheroids.
In: Iscience, Bd. 24, Nr. 3, 102185
Deiringer, Natalie; Haase, Christian; Wieland, Karin; Zahler, Stefan; Haisch, Christoph und Frieß, Wolfgang
(2021):
Finding the Needle in the Haystack: High-Resolution Techniques for Characterization of Mixed Protein Particles Containing Shed Silicone Rubber Particles Generated During Pumping.
In: Journal of Pharmaceutical Sciences, Bd. 110, Nr. 5: S. 2093-2104
Karg, Cornelia A.; Wang, Shuaijun; Al Danaf, Nader; Pemberton, Ryan P.; Bernard, Denzil; Kretschmer, Maibritt; Schneider, Sabine; Zisis, Themistoklis; Vollmar, Angelika M.; Lamb, Don C.; Zahler, Stefan und Moser, Simone
(2021):
Tetrapyrrolic Pigments from Heme- and Chlorophyll Breakdown are Actin-Targeting Compounds.
In: Angewandte Chemie-International Edition, Bd. 60, Nr. 41: S. 22578-22584
Kretschmer, Maibritt; Ruediger, Daniel und Zahler, Stefan
(2021):
Mechanical Aspects of Angiogenesis.
In: Cancers, Bd. 13, Nr. 19, 4987
Müller, Martin; Gerndt, Susanne; Chao, Yu-Kai; Zisis, Themistoklis; Ong, Nam Phuong Nguyen; Gerwien, Aaron; Urban, Nicole; Müller, Christoph; Gegenfurtner, Florian A.; Geisslinger, Franz; Ortler, Carina; Chen, Cheng-Chang; Zahler, Stefan; Biel, Martin; Schäfer, Michael; Grimm, Christian; Bracher, Franz; Vollmar, Angelika M. und Bartel, Karin
(2021):
Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth.
In: Cell Chemical Biology, Bd. 28, Nr. 8:
1119-
Passi, Mehak und Zahler, Stefan
(2021):
Mechano-Signaling Aspects of Hepatocellular Carcinoma.
In: Journal of Cancer, Bd. 12, Nr. 21: S. 6411-6421
Wang, Shuaijun; Meixner, Maximilian; Yu, Lushuang; Zhuo, Ling; Karmann, Lisa; Kazmaier, Uli; Vollmar, Angelika M.; Antes, Iris und Zahler, Stefan
(2021):
Turning the Actin Nucleating Compound Miuraenamide into Nucleation Inhibitors.
In: ACS Omega, Bd. 6, Nr. 34: S. 22165-22172
Zisis, Themistoklis; Schwarz, Jan; Balles, Miriam; Kretschmer, Maibritt; Nemethova, Maria; Chait, Remy; Hauschild, Robert; Lange, Janina; Guet, Calin; Sixt, Michael und Zahler, Stefan
(2021):
Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal Control.
In: ACS Applied Materials & Interfaces, Bd. 13, Nr. 30: S. 35545-35560
Rüdiger, Daniel; Kick, Kerstin; Goychuk, Andriy; Vollmar, Angelika M.; Frey, Erwin und Zahler, Stefan
(2020):
Cell-Based Strain Remodeling of a Nonfibrous Matrix as an Organizing Principle for Vasculogenesis.
In: Cell Reports, Bd. 32, Nr. 6, 108015
Unzue, Andrea; Jessen-Trefzer, Claudia; Spiliotopoulos, Dimitrios; Gaudio, Eugenio; Tarantelli, Chiara; Dong, Jing; Zhao, Hongtao; Pachmayr, Johanna; Zahler, Stefan; Bernasconi, Elena; Sartori, Giulio; Cascione, Luciano; Bertoni, Francesco; Sledz, Pawel; Caflisch, Amedeo und Nevado, Cristina
(2020):
Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors.
In: Rsc Medicinal Chemistry, Bd. 11, Nr. 6: S. 665-675
Borowiak, Malgorzata; Kuellmer, Florian; Gegenfurtner, Florian; Peil, Sebastian; Nasufovic, Veselin; Zahler, Stefan; Thorn-Seshold, Oliver; Trauner, Dirk und Arndt, Hans-Dieter
(2020):
Optical Manipulation of F-Actin with Photoswitchable Small Molecules.
In: Journal of the American Chemical Society, Bd. 142, Nr. 20: S. 9240-9249
Meena, Chhuttan L.; Singh, Dharmendra; Weinmueller, Michael; Reichart, Florian; Dangi, Abha; Marelli, Udaya Kiran; Zahler, Stefan und Sanjayan, Gangadhar J.
(2020):
Novel cilengitide-based cyclic RGD peptides as alpha nu beta(3) integrin inhibitors.
In: Bioorganic & Medicinal Chemistry Letters, Bd. 30, Nr. 8, 127039
Zahler, Stefan
(2020):
Nuclear actin in cancer biology.
In: International review of cell and molecular biology, Bd. 355: S. 53-66
Ploetz, Evelyn; Zimpel, Andreas; Cauda, Valentina; Bauer, David; Lamb, Don C.; Haisch, Christoph; Zahler, Stefan; Vollmar, Angelika M.; Wuttke, Stefan und Engelke, Hanna
(2020):
Metal–Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH.
In: Advanced Materials, Bd. 32, Nr. 19, 1907267
[PDF, 1MB]
Wang, Shuaijun; Crevenna, Alvaro H.; Ugur, Ilke; Marion, Antoine; Antes, Iris; Kazmaier, Uli; Hoyer, Maria; Lamb, Don C.; Gegenfurtner, Florian; Kliesmetes, Zane; Ziegenhain, Christoph; Enard, Wolfgang; Vollmar, Angelika und Zahler, Stefan
(2019):
Actin stabilizing compounds show specific biological effects due to their binding mode.
In: Scientific Reports, Bd. 9, 9731
[PDF, 5MB]
Ardelt, Maximilian A.; Fröhlich, Thomas; Martini, Emanuele; Müller, Martin; Kanitz, Veronika; Atzberger, Carina; Cantonati, Petra; Messner, Martina; Posselt, Laura; Lehr, Thorsten; Wojtyniak, Jan-Georg; Ulrich, Melanie; Arnold, Georg J.; König, Lars; Parazzoli, Dario; Zahler, Stefan; Rothenfusser, Simon; Mayr, Doris; Gerbes, Alexander; Scita, Giorgio; Vollmar, Angelika M. und Pachmayr, Johanna
(2019):
Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.
In: Hepatology, Bd. 69, Nr. 1: S. 376-393
Ljepoja, Bojan; Schreiber, Christoph; Gegenfurtner, Florian A.; Garcia-Roman, Jonathan; Köhler, Bianca; Zahler, Stefan; Rädler, Joachim O.; Wagner, Ernst und Roidl, Andreas
(2019):
Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A.
In: PLOS One 14(11), e0224314 [PDF, 2MB]
In: PLOS One 14(11), e0224314 [PDF, 2MB]
Geiger, Florian; Rüdiger, Daniel; Zahler, Stefan und Engelke, Hanna
(2019):
Fiber stiffness, pore size and adhesion control migratory phenotype of MDA-MB-231 cells in collagen gels.
In: PLOS One 14(11), e0225215 [PDF, 2MB]
In: PLOS One 14(11), e0225215 [PDF, 2MB]
Wang, Shuaijun; Gegenfurtner, Florian A.; Crevenna, Alvaro H.; Ziegenhain, Christoph; Kliesmete, Zane; Enard, Wolfgang; Müller, Rolf; Vollmar, Angelika M.; Schneider, Sabine und Zahler, Stefan
(2019):
Chivosazole A Modulates Protein Protein Interactions of Actin.
In: Journal of Natural Products, Bd. 82, Nr. 7: S. 1961-1970
Kern, Sarah; Truebenbach, Ines; Hoehn, Miriam; Gorges, Jan; Kazmaier, Uli; Zahler, Stefan; Vollmar, Angelika M. und Wagner, Ernst
(2019):
Combined antitumoral effects of pretubulysin and methotrexate.
In: Pharmacology Research & Perspectives, Bd. 7, Nr. 1, UNSP e00460
Bryce, Nicole S.; Failes, Tim W.; Stehn, Justine R.; Baker, Karen; Zahler, Stefan; Arzhaeva, Yulia; Bischof, Leanne; Lyons, Ciaran; Dedova, Irina; Arndt, Greg M.; Gaus, Katharina; Goult, Benjamin T.; Hardeman, Edna C.; Gunning, Peter W. und Lock, John G.
(2019):
High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained.
In: Cell Systems, Bd. 9, Nr. 5
Pfitzer, Lisa; Moser, Christina; Gegenfurtner, Florian; Arner, Anja; Foerster, Florian; Atzberger, Carina; Zisis, Themistoklis; Kubisch-Dohmen, Rebekka; Busse, Johanna; Smith, Rebecca; Timinszky, Gyula; Kalinina, Olga V.; Müller, Rolf; Wagner, Ernst; Vollmar, Angelika M. und Zahler, Stefan
(2019):
Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.
In: Cell Death & Disease, Bd. 10, UNSP 302
Koczian, Fabian; Naglo, Olga; Vomacka, Jan; Vick, Binje; Servatius, Phil; Zisis, Themistoklis; Hettich, Britta; Kazmaier, Uli; Sieber, Stephan A.; Jeremias, Irmela; Zahler, Stefan und Braig, Simone
(2019):
Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics.
In: Haematologica, Bd. 104, Nr. 3: S. 546-555
Praetner, Marc; Zuchtriegel, Gabriele; Holzer, Martin; Uhl, Bernd; Schaubaecher, Johanna; Mittmann, Laura; Fabritius, Matthias; Fürst, Robert; Zahler, Stefan; Funken, Dominik; Lerchenberger, Maximilian; Khandoga, Andrej; Kanse, Sandip; Lauber, Kirsten; Krombach, Fritz und Reichel, Christoph A.
(2018):
Plasminogen Activator Inhibitor-1 Promotes Neutrophil Infiltration and Tissue Injury on Ischemia–Reperfusion.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 4: S. 829-842
[PDF, 2MB]
Stoiber, Katharina; Naglo, Olga; Pernpeintner, Carla; Zhang, Siwei; Köberle, Andreas; Ulrich, Melanie; Werz, Oliver; Müller, Rolf; Zahler, Stefan; Lohmüller, Theobald; Feldmann, Jochen und Braig, Simone
(2018):
Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.
In: British Journal of Cancer, Bd. 118, Nr. 1: S. 43-51
Gegenfurtner, Florian A.; Jahn, Berenice; Wagner, Helga; Ziegenhain, Christoph; Enard, Wolfgang; Geistlinger, Ludwig; Rädler, Joachim O.; Vollmar, Angelika M. und Zahler, Stefan
(2018):
Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing.
In: Journal of Cell Science, Bd. 131, Nr. 10
Gegenfurtner, Florian A.; Zisis, Themistoklis; Al Danaf, Nader; Schrimpf, Waldemar; Kliesmete, Zane; Ziegenhain, Christoph; Enard, Wolfgang; Kazmaier, Uli; Lamb, Don C.; Vollmar, Angelika M. und Zahler, Stefan
(2018):
Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone.
In: Cellular and Molecular Life Sciences, Bd. 75, Nr. 24: S. 4539-4555
Rarova, Lucie; Sedlak, David; Oklestkova, Jana; Steigerova, Jana; Liebl, Johanna; Zahler, Stefan; Bartunek, Petr; Kolar, Zdenek; Kohout, Ladislav; Kvasnica, Miroslav und Strnad, Miroslav
(2018):
The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro.
In: Journal of Steroid Biochemistry and Molecular Biology, Bd. 178: S. 263-271
Yordanova, Yordanka; Vanderlinden, Willem; Stoll, Raphael; Rüdiger, Daniel; Tosstorff, Andreas; Zaremba, Wolfgang; Winter, Gerhard; Zahler, Stefan und Friess, Wolfgang
(2018):
Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils.
In: Scientific Reports, Bd. 8, 11280
[PDF, 3MB]
Kappler, Sarah; Karmann, Lisa; Prudel, Cynthia; Herrmann, Jennifer; Caddeu, Giulia; Müller, Rolf; Vollmar, Angelika M.; Zahler, Stefan und Kazmaier, Uli
(2018):
Synthesis and Biological Evaluation of Modified Miuraenamides.
In: European Journal of Organic Chemistry, Nr. 48: S. 6952-6965
Pergola, Carlo; Schubert, Katrin; Pace, Simona; Ziereisen, Jana; Nikels, Felix; Scherer, Olga; Hüttel, Stephan; Zahler, Stefan; Vollmar, Angelika M.; Weinigel, Christina; Rummler, Silke; Müller, Rolf; Raasch, Martin; Mosig, Alexander; Koeberle, Andreas und Werz, Oliver
(2017):
Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy.
In: Scientific Reports, Bd. 7, 41434
[PDF, 3MB]
Paulus, Constanze; Rebets, Yuriy; Tokovenko, Bogdan; Nadmid, Suvd; Terekhova, Larisa P.; Myronovskyi, Maksym; Zotchev, Sergey B.; Rückert, Christian; Braig, Simone; Zahler, Stefan; Kalinowski, Jörn und Luzhetskyy, Andriy
(2017):
New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp MP131-18.
In: Scientific Reports, Bd. 7, 42382
[PDF, 2MB]
Pozo, Karine; Ishimatsu, Keisuke; Telange, Rahul; Takahashi, Masaya; Oltmann, Sarah; Zahler, Stefan und Bibb, James
(2017):
Novel Combinatorial Drug Therapy for MTC.
In: Pancreas, Bd. 46, Nr. 3: S. 428-429
Zhang, Peng; Steinborn, Benjamin; Lächelt, Ulrich; Zahler, Stefan und Wagner, Ernst
(2017):
Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery.
In: Biomacromolecules, Bd. 18, Nr. 8: S. 2509-2520
Moser, Christina; Rüdiger, Daniel; Foerster, Florian; Blume, Julia von; Yu, Peng; Kuster, Bernhard; Kazmaier, Uli; Vollmar, Angelika M. und Zahler, Stefan
(2017):
Persistent inhibition of pore-based cell migration by sub-toxic doses of miuraenamide, an actin filament stabilizer.
In: Scientific Reports, Bd. 7, 16407
[PDF, 1MB]
Fuchs, Simone; Bischoff, Iris; Willer, Elisabeth A.; Bräutigam, Jacqueline; Bubik, Martin F.; Erdelmeier, Clemens A. J.; Koch, Egon; Faleschini, Maria T.; Mieri, Maria de; Bauhart, Milena; Zahler, Stefan; Hensel, Andreas; Hamburger, Matthias; Potterat, Olivier und Fürst, Robert
(2017):
The Dual Edema-Preventing Molecular Mechanism of the Crataegus Extract WS 1442 Can Be Assigned to Distinct Phytochemical Fractions.
In: Planta Medica, Bd. 83, Nr. 8: S. 701-709
Merk, Henriette; Messer, Philipp; Ardelt, Maximilian A.; Lamb, Don C.; Zahler, Stefan; Müller, Rolf; Vollmar, Angelika M. und Pachmayr, Johanna
(2017):
Inhibition of the V-ATPase by Archazolid A: A New Strategy to Inhibit EMT.
In: Molecular Cancer therapeutics, Bd. 16, Nr. 11: S. 2329-2339
Schuster, Simon L.; Segerer, Felix J.; Gegenfurtner, Florian A.; Kick, Kerstin; Schreiber, Christoph; Albert, Max; Vollmar, Angelika M.; Rädler, Joachim O. und Zahler, Stefan
(2016):
Contractility as a global regulator of cellular morphology, velocity, and directionality in low-adhesive fibrillary micro-environments.
In: Biomaterials, Bd. 102: S. 137-147
Kick, Kerstin; Nekolla, Katharina; Rehberg, Markus; Vollmar, Angelika M. und Zahler, Stefan
(2016):
New View on Endothelial Cell Migration Switching Modes of Migration Based on Matrix Composition.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 12: S. 2346-2357
Herzog, Julia; Ehrlich, Sandra M.; Pfitzer, Lisa; Liebl, Johanna; Fröhlich, Thomas; Arnold, Georg J.; Mikulits, Wolfgang; Haider, Christine; Vollmar, Angelika M. und Zahler, Stefan
(2016):
Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1 alpha: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma.
In: Oncotarget, Bd. 7, Nr. 19: S. 27108-27121
Merk, Henriette; Zhang, Siwei; Lehr, Thorsten; Müller, Christoph; Ulrich, Melanie; Bibb, James A.; Adams, Ralf H.; Bracher, Franz; Zahler, Stefan; Vollmar, Angelika M. und Liebl, Johanna
(2016):
Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis.
In: Oncotarget, Bd. 7, Nr. 5: S. 6088-6104
Unzue, Andrea; Lafleur, Karine; Zhao, Hongtao; Zhou, Ting; Dong, Jing; Kolb, Peter; Liebl, Johanna; Zahler, Stefan; Caflisch, Amedeo und Nevado, Cristina
(2016):
Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation.
In: European Journal of Medicinal Chemistry, Bd. 112: S. 347-366
Segerer, Felix Jakob; Röttgermann, Peter Johan Friedrich; Schuster, Simon; Alberola, Alicia Piera; Zahler, Stefan und Rädler, Joachim O.
(2016):
Versatile method to generate multiple types of micropatterns.
In: Biointerphases, Bd. 11, Nr. 1, 11005
Pfeiler, Susanne; Khandagale, Avinash B.; Magenau, Astrid; Nichols, Maryana; Heijnen, Harry F. G.; Rinninger, Franz; Ziegler, Tilman; Seveau, Stephanie; Schubert, Sören; Zahler, Stefan; Verschoor, Admar; Latz, Eicke; Massberg, Steffen; Gaus, Katharina und Engelmann, Bernd
(2016):
Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI.
In: Scientific Reports, Bd. 6, 34440
[PDF, 6MB]
Reichel, Christoph A.; Hessenauer, Maximilian E. T.; Pflieger, Kerstin; Rehberg, Markus; Kanse, Sandip M.; Zahler, Stefan; Krombach, Fritz; Berghaus, Alexander und Strieth, Sebastian
(2015):
Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects.
In: PLOS ONE 10(2), e0116883 [PDF, 4MB]
In: PLOS ONE 10(2), e0116883 [PDF, 4MB]
Arends, Fabienna; Nowald, Constantin; Pflieger, Kerstin; Boettcher, Kathrin; Zahler, Stefan und Lieleg, Oliver
(2015):
The Biophysical Properties of Basal Lamina Gels Depend on the Biochemical Composition of the Gel.
In: PLOS ONE 10(2), e0118090 [PDF, 2MB]
In: PLOS ONE 10(2), e0118090 [PDF, 2MB]
Liebl, Johanna; Zhang, Siwei; Moser, Markus; Agalarov, Yan; Demir, Cansaran Saygili; Hager, Bianca; Bibb, James A.; Adams, Ralf H.; Kiefer, Friedemann; Miura, Naoyuki; Petrova, Tatiana V.; Vollmar, Angelika M. und Zahler, Stefan
(2015):
Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2.
In: Nature Communications, Bd. 6, 7274
[PDF, 2MB]
Braig, Simone; Schmidt, B. U. Sebastian; Stoiber, Katharina; Haendel, Chris; Moehn, Till; Werz, Oliver; Mueller, Rolf; Zahler, Stefan; Koeberle, Andreas; Kaes, Josef A. und Vollmar, Angelika M.
(2015):
Pharmacological targeting of membrane rigidity: implications on cancer cell migration and invasion.
In: New Journal of Physics, Bd. 17, 083007
[PDF, 1MB]
Menhofer, Magdalena H.; Kubisch, Rebekka; Schreiner, Laura; Zorn, Matthias; Foerster, Florian; Mueller, Rolf; Rädler, Joachim O.; Wagner, Ernst; Vollmar, Angelika M. und Zahler, Stefan
(2014):
The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility.
In: PLOS ONE 9(11), e112542 [PDF, 1MB]
In: PLOS ONE 9(11), e112542 [PDF, 1MB]
Mayer, Bettina A.; Rehberg, Markus; Erhardt, Annette; Wolf, Alexander; Reichel, Christoph A.; Kracht, Michael; Krombach, Fritz; Tiegs, Gisa; Zahler, Stefan; Vollmar, Angelika M. und Fürst, Robert
(23. Januar 2013):
Inhibitor of Apoptosis Proteins as Novel Targets in Inflammatory Processes.
In: Arteriosclerosis, thrombosis, and vascular biology, Bd. 31, Nr. 10: S. 2240-2250
[PDF, 1MB]
Weitensteiner, Sabine B.; Liebl, Johanna; Krystof, Vladimir; Havlíček, Libor; Gucký, Tomáš; Strnad, Miroslav; Fürst, Robert; Vollmar, Angelika M. und Zahler, Stefan
(2013):
Trisubstituted pyrazolopyrimidines as novel angiogenesis inhibitors.
In: PLOS ONE 8(1), e54607 [PDF, 3MB]
In: PLOS ONE 8(1), e54607 [PDF, 3MB]
Egea, Virginia; Zahler, Stefan; Rieth, Nicole; Neth, Peter; Popp, Tanja; Kehe, Kai; Jochum, Marianne und Ries, Christian
(2012):
Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 109, Nr. 6, E309-E316
[PDF, 1MB]
Eirich, Jürgen; Burkhart, Jens L.; Ullrich, Angelika; Rudolf, Georg C.; Vollmar, Angelika M.; Zahler, Stefan; Kazmaier, Uli und Sieber, Stephan A.
(2012):
Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy.
In: Molecular BioSystems, Bd. 8, Nr. 8: S. 2067-2075
[PDF, 3MB]
Reichel, Christoph A.; Uhl, Bernd; Lerchenberger, Max; Puhr-Westerheide, Daniel; Rehberg, Markus; Liebl, Johanna; Khandoga, Andrej; Schmalix, Wolfgang; Zahler, Stefan; Deindl, Elisabeth; Lorenzl, Stefan; Declerck, Paul J.; Kanse, Sandip und Krombach, Fritz
(25. Oktober 2011):
Urokinase-Type Plasminogen Activator Promotes Paracellular Transmigration of Neutrophils Via Mac-1, But Independently of Urokinase-Type Plasminogen Activator Receptor.
In: Circulation, Bd. 124, Nr. 17: S. 1848-1859
[PDF, 4MB]
Reichel, Christoph A.; Lerchenberger, Max; Uhl, Bernd; Rehberg, Markus; Berberich, Nina; Zahler, Stefan; Wymann, Matthias P. und Krombach, Fritz
(Januar 2011):
Plasmin Inhibitors Prevent Leukocyte Accumulation and Remodeling Events in the Postischemic Microvasculature.
In: PLOS ONE 6(2), e17229 [PDF, 2MB]
In: PLOS ONE 6(2), e17229 [PDF, 2MB]
Schmerwitz, Ulrike K.; Sass, Gabriele; Khandoga, Alexander G.; Joore, Jos; Mayer, Bettina A.; Berberich, Nina; Totzke, Frank; Krombach, Fritz; Tiegs, Gisa; Zahler, Stefan; Vollmar, Angelika M. und Fürst, Robert
(2011):
Flavopiridol Protects Against Inflammation by Attenuating Leukocyte-Endothelial Interaction via Inhibition of Cyclin-Dependent Kinase 9.
In: Arteriosclerosis, thrombosis, and vascular biology, Bd. 31, Nr. 2: S. 280-288
[PDF, 979kB]
Zengel, Pamela; Ramp, Diana; Mack, Brigitte; Zahler, Stefan; Berghaus, Alexander; Muehlenweg, Bernd; Gires, Olivier und Schmitz, Suna
(2010):
Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis.
In: BMC cancer, Nr. 92
[PDF, 1MB]
Reichel, Christoph A.; Rehberg, Markus; Lerchenberger, Max; Berberich, Nina; Bihari, Peter; Khandoga, Alexander G.; Zahler, Stefan und Krombach, Fritz
(2009):
Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators.
In: Arteriosclerosis, thrombosis, and vascular biology, Bd. 29, Nr. 11: S. 1787-1793
[PDF, 381kB]
Hoffmann, F.; Sass, G.; Zillies, Jan; Zahler, Stefan; Fuchs, S.; Wagner, J.; Winter, Gerhard; Coester, C.; Gerbes, Alexander L. und Vollmar, Angelika M.
(2009):
A novel technique for selective NF-kappa B inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion.
In: Gut, Bd. 58:
1670-1678.
[PDF, 2MB]
Hartkorn, Andreas; Hoffmann, Florian; Ajamieh, Hussam; Vogel, Susanne; Heilmann, Jörg; Gerbes, Alexander L.; Vollmar, Angelika M. und Zahler, Stefan
(2009):
Antioxidant Effects of Xanthohumol and Functional Impact on Hepatic Ischemia-Reperfusion Injury.
In: Journal of natural products, Bd. 72: S. 1741-1747
[PDF, 2MB]
Rothmeier, Andrea S.; Ischenko, Ivan; Joore, Jos; Garczarczyk, Dorota; Fürst, Robert; Bruns, Christiane J.; Vollmar, Angelika M. und Zahler, Stefan
(2009):
Investigation of the marine compound spongistatin 1 links the inhibition of PKCα translocation to nonmitotic effects of tubulin antagonism in angiogenesis.
In: The FASEB journal, Bd. 23, Nr. 4: S. 1127-1137
[PDF, 923kB]
Fürst, Robert; Bubik, Martin F.; Bihari, Peter; Mayer, Bettina A.; Khandoga, Alexander G.; Hoffmann, Florian; Rehberg, Markus; Krombach, Fritz; Zahler, Stefan und Vollmar, Angelika M.
(August 2008):
Atrial Natriuretic Peptide Protects against Histamine-Induced Endothelial Barrier Dysfunction in Vivo.
In: Molecular pharmacology, Bd. 74, Nr. 1
[PDF, 1MB]
Fürst, Robert; Zahler, Stefan und Vollmar, Angelika M.
(2008):
Dexamethasone-Induced Expression of Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Involves Activation of the Transcription Factors Activator Protein-1 and 3',5'-Cyclic Adenosine 5'-Monophosphate Response Element-Binding Protein and the Generation of Reactive Oxygen Species.
In: Endocrinology, Bd. 149, Nr. 7: S. 3635-3642
[PDF, 276kB]
Ries, Christian; Pitsch, Thomas; Mentele, Reinhard; Zahler, Stefan; Egea, Virginia; Nagase, Hideaki und Jochum, Marianne
(2007):
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells. (auto-)catalytic activation and resistance to inhibition by TIMP-1.
In: The biochemical journal, Nr. 405: S. 547-558
[PDF, 886kB]
Fürst, Robert; Schroeder, Timm; Eilken, Hanna M.; Bubik, Martin F.; Kiemer, Alexandra K.; Zahler, Stefan und Vollmar, Angelika M.
(2007):
MAPK phosphatase-1 represents a novel antiinflammatory target of glucocorticoids in the human endothelium.
In: The FASEB journal, Bd. 21, Nr. 1: S. 74-80
[PDF, 280kB]
Ladetzki-Baehs, Kathrin; Keller, Melanie; Kiemer, Alexandra K.; Koch, Elke; Zahler, Stefan; Wendel, Albrecht und Vollmar, Angelika M.
(2007):
Atrial Natriuretic Peptide, a Regulator of Nuclear Factor-κB Activation in Vivo.
In: Endocrinology, Bd. 148, Nr. 1: S. 332-336
[PDF, 185kB]
Fürst, Robert; Blumenthal, Signe B.; Kiemer, Alexandra K.; Zahler, Stefan und Vollmar, Angelika M.
(2006):
Nuclear Factor-κB-Independent Anti-Inflammatory Action of Salicylate in Human Endothelial Cells. Induction of Heme Oxygenase-1 by the c-Jun N-Terminal Kinase/Activator Protein-1 Pathway.
In: The journal of pharmacology and experimental therapeutics, Bd. 318, Nr. 1: S. 389-394
[PDF, 399kB]
Fürst, Robert; Brueckl, Corinna; Kuebler, Wolfgang M.; Zahler, Stefan; Krötz, Florian; Görlach, Agnes; Vollmar, Angelika M. und Kiemer, Alexandra K.
(2005):
Atrial Natriuretic Peptide Induces Mitogen-Activated Protein Kinase Phosphatase-1 in Human Endothelial Cells via Rac1 and NAD(P)H Oxidase/Nox2-Activation.
In: Circulation research, Bd. 96, Nr. 1: S. 43-53
[PDF, 671kB]
Blumenthal, Signe B.; Kiemer, Alexandra K.; Tiegs, Gisa; Seyfried, Stefan; Höltje, Monika; Brandt, Birte; Höltje, Hans-Dieter; Zahler, Stefan und Vollmar, Angelika M.
(2005):
Metalloporphyrins inactivate caspase-3 and -8.
In: The FASEB journal, Bd. 19, Nr. 10: S. 1272-1279
[PDF, 324kB]
Zahler, Stefan; Hoffmann, Anke; Gloe, Torsten und Pohl, Ulrich
(Januar 2003):
Gap-junctional coupling between neutrophils and endothelial cells. A novel modulator of transendothelial migration.
In: Journal of Leukocyte Biology, Bd. 73, Nr. 1: S. 118-126
[PDF, 429kB]
Sohn, Hae-Young; Krötz, Florian; Zahler, Stefan; Gloe, Torsten; Keller, Matthias; Theisen, Karl; Schiele, Thomas M.; Klauss, Volker und Pohl, Ulrich
(2003):
Crucial role of local peroxynitrite formation in neutrophil-induced endothelial cell activation.
In: Cardiovascular Research, Bd. 57, Nr. 3: S. 804-815
[PDF, 2MB]
Koczulla, Rembert; Degenfeld, Georges von; Kupatt, Christian; Krötz, Florian; Zahler, Stefan; Gloe, Torsten; Issbrücker, Katja; Unterberger, Pia; Zaiou, Mohamed; Lebherz, Corinna; Karl, Alexander; Raake, Philip; Pfosser, Achim; Boekstegers, Peter; Welsch, Ulrich; Hiemstra, Pieter S.; Vogelmeier, Claus; Gallo, Richard L.; Clauss, Matthias und Bals, Robert
(2003):
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.
In: The Journal of Clinical Investigation, Bd. 111, Nr. 11: S. 1665-1672
[PDF, 2MB]
Willeke, Thomas; Schymeinsky, Jürgen; Prange, Peggy; Zahler, Stefan und Walzog, Barbara
(2003):
A role for Syk-kinase in the control of the binding cycle of the β2 integrins (CD11/CD18) in human polymorphonuclear neutrophils.
In: Journal of Leukocyte Biology, Bd. 74, Nr. 2: S. 260-269
[PDF, 413kB]
Hoffmann, Anke; Gloe, Torsten; Pohl, Ulrich und Zahler, Stefan
(2003):
Nitric oxide enhances de novo formation of endothelial gap junctions.
In: Cardiovascular Research, Bd. 60, Nr. 2: S. 421-430
[PDF, 635kB]
Gilles, Stefanie; Zahler, Stefan; Welsch, Ulrich; Sommerhoff, Christian P. und Becker, Bernhard F.
(2003):
Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers.
In: Cardiovascular Research, Bd. 60, Nr. 3: S. 608-616
[PDF, 637kB]
Müller, Ingrid; Klocke, Antje; Alex, Meike; Kotzsch, Matthias; Luther, Thomas; Morgenstern, Eberhard; Zieseniss, Susanne; Zahler, Stefan; Preissner, Klaus und Engelmann, Bernd
(2003):
Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets.
In: The FASEB Journal, Bd. 17, Nr. 3: S. 476
[PDF, 1MB]
Becker, Bernhard F.; Gilles, Stefanie; Sommerhoff, Christian P. und Zahler, Stefan
(2002):
Application of Peptides Containing the Cleavage Sequence of Pro-TNFα in Assessing TACE Activity of Whole Cells.
In: Biological chemistry, Bd. 383, Nr. 11: S. 1821-1826
[PDF, 189kB]
Zahler, Stefan; Kupatt, Christian und Becker, Bernhard F.
(2000):
Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α.
In: The FASEB journal, Bd. 14, Nr. 3: S. 555-564
[PDF, 417kB]
Kupatt, Christian; Habazettl, Helmut; Goedecke, Axel; Wolf, Dieter A.; Zahler, Stefan; Boekstegers, Peter; Kelly, Ralph A. und Becker, Bernhard F.
(5. März 1999):
Tumor Necrosis Factor-α Contributes to Ischemia- and Reperfusion-Induced Endothelial Activation in Isolated Hearts.
In: Circulation research, Bd. 84, Nr. 4: S. 392-400
[PDF, 300kB]
Zahler, Stefan; Massoudy, Parwis; Hartl, Heinz; Hähnel, Christoph; Meisner, Hans und Becker, Bernhard F.
(1999):
Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass.
In: Cardiovascular Research, Bd. 41, Nr. 3: S. 722-730
[PDF, 272kB]
Heindl, Bernhard; Zahler, Stefan; Welsch, Ulrich und Becker, Bernhard F.
(1998):
Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts.
In: Cardiovascular Research, Bd. 38, Nr. 2: S. 383-394
[PDF, 1MB]
Kupatt, Christian; Habazettl, Helmut; Zahler, Stefan; Weber, Christian; Becker, Bernhard F.; Messmer, Konrad und Gerlach, Eckehart
(1997):
ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury.
In: Cardiovascular Research, Bd. 36, Nr. 3: S. 386-395
[PDF, 2MB]
Zahler, Stefan; Becker, Bernhard F.; Raschke, P. und Gerlach, E.
(1994):
Stimulation of endothelial adenosine Al receptors enhances adhesion of neutrophils in the intact guinea pig coronary system.
In: Cardiovascular research, Bd. 28, Nr. 9: S. 1366-1372
[PDF, 895kB]
Schumacher, U.; Zahler, Stefan; Horny, H.-P.; Heidemann, Günter; Skirnisson, K. und Welsch, U.
(1993):
Histological investigations on the thyroid glands of marine mammals (Phoca vitulina, Phocoena phocoena) and the possible implications of marine pollution.
In: Journal of wildlife diseases, Bd. 29, Nr. 1: S. 103-108
[PDF, 896kB]
Gardner, A.; Odebralski, J.; Zahler, Stefan; Korman, R. Z. und Aronson, A. I.
(1982):
Glutamine synthetase subunit mixing and regulation in Bacillus subtilis partial diploids.
In: Journal of Bacteriology, Bd. 149, Nr. 1: S. 378-380
[PDF, 476kB]