ORCID: https://orcid.org/0000-0002-1313-4089; Dawson, Simon J.; Langhorn, Line M.; Howard, Ryan T.; Kwon, Sunbum ORCID: https://orcid.org/0000-0003-0027-6990; Douat, Céline ORCID: https://orcid.org/0000-0003-2678-1047; Suga, Hiroaki ORCID: https://orcid.org/0000-0002-5298-9186 und Huc, Ivan ORCID: https://orcid.org/0000-0001-7036-9696
(2025):
Display selection of peptide ligands for helical aromatic foldamers.
In: Organic & Biomolecular Chemistry, Vol. 23, No. 19: pp. 4641-4647
[PDF, 1MB]
Abstract
Helical aromatic oligoamide foldamers with a cluster of five biogenic side chains at their surface were designed and synthesized. Display selection of thioether macrocyclic peptides against these targets generated low micromolar binders that are highly selective for the side-chain arrangement.
| Item Type: | Journal article |
|---|---|
| Faculties: | Chemistry and Pharmacy > Department of Pharmacy |
| Subjects: | 500 Science > 540 Chemistry |
| URN: | urn:nbn:de:bvb:19-epub-129281-7 |
| ISSN: | 1477-0520 |
| Language: | English |
| Item ID: | 129281 |
| Date Deposited: | 05. Nov 2025 08:49 |
| Last Modified: | 05. Nov 2025 08:49 |
| DFG: | Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 325871075 |
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