Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference

Frost, Bess; Rowe, James B.; Akinyemi, Rufus O.; Abisambra, Jose F.; Ashton, Nicholas J.; Brendel, Matthias ; Buée, Luc; Butler, David; Carrillo, Maria C.; Chung, Peter; Clelland, Claire D.; DeVos, Sarah L.; Diaz, Kristophe; Edelmayer, Rebecca M.; Elahi, Fanny M.; Ellajosyula, Ratnavalli; Ewen, Colin; Fontana, Igor Camargo; Galas, Marie‐Christine; Hansson, Oskar; Höglinger, Günter ; Horie, Kanta; Ibanez, Agustín; Jacobs, Linde; Maina, Mahmoud B.; Malpetti, Maura; McDade, Eric; McEwan, Will; Montoliu‐Gaya, Laia; Mummery, Catherine J.; Orr, Miranda E.; Rohrer, Jonathan D.; Rommel, Amy; Sastre, Carlos; Spires‐Jones, Tara L.; Tee, Boon Lead; Viney, Tim J.; Walker, Jamie M.; Wegmann, Susanne; Wildsmith, Kristin; Yadav, Ravi; Mahinrad, Simin und Sexton, Claire (2025): Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference. In: Alzheimer's & Dementia, Vol. 21, No. 5, e70078

Abstract

Recent years have seen major advances in tau-associated brain disorders through interdisciplinary research spanning molecular biology, neuroimaging, clinical trials, and therapeutic development. The Tau2024 Global Conference, hosted by the Alzheimer's Association, CurePSP, and Rainwater Charitable Foundation, showcased these efforts by bringing together researchers and experts worldwide to discuss the latest advancements in tau research. The conference aimed to attract talent and funding to study tauopathies, particularly among early-career researchers, and to foster interdisciplinary alignment and collaboration around challenges in tau research. In this manuscript, we summarize proceedings of the Tau2024 Global Conference, covering a wide range of topics, including lived experiences of individuals with genetic forms of tauopathies, global perspectives on tauopathies, and molecular mechanisms, brain microenvironments, biomarker developments, clinical trials, and therapeutic approaches to tauopathies. Through international, collaborative efforts, innovative research, and a commitment to inclusivity, researchers worldwide have demonstrated transformative breakthroughs toward diagnosing, treating, and, ultimately, preventing tau-related diseases.

• Item Type: Journal article
• Faculties: Medicine > Munich Cluster for Systems Neurology (SyNergy); Medicine > Medical Center of the University of Munich > Clinic and Polyclinic for Nuclear Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 1552-5260
• Language: English
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 390857198