Cui, Tiantian; Chen, Yuan; Yang, Linlin; Mireskandari, Masoud; Knösel, Thomas; Zhang, Qing; Kohler, Lukas Herbert; Kunze, Almut; Presselt, Norbert; Petersen, Iver
Diagnostic and prognostic impact of desmocollins in human lung cancer.
In: Journal of clinical pathology, Vol. 65, No. 12: pp. 1100-1106
Desmosomes are intercellular junctions that confer strong cell-cell adhesion. Two main members of desmosomal cadherins, desmogleins (DSGs) and desmocollins (DSCs), are involved in carcinogenesis. However, their role in human lung cancer remained elusive. The aims of this study were to analyse the expression of DSCs and to evaluate their clinical application in lung cancer.