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Gattner, Michael J.; Ehrlich, Michael; Vrabel, Milan (29. August 2014): Sulfonyl azide-mediated norbornene aziridination for orthogonal peptide and protein labeling. In: Chemical Communications, Vol. 50, Nr. 83: S. 12568-12571
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Abstract

We describe a new bioconjugation reaction based on the aziridination of norbornenes using electron-deficient sulfonyl azides. The reaction enables to attach various useful tags to peptides and proteins under mild conditions.