What is personalized medicine: sharpening a vague term based on a systematic literature review

Schleidgen, Sebastian; Klingler, Corinna; Bertram, Teresa; Rogowski, Wolf H. und Marckmann, Georg (2013): What is personalized medicine: sharpening a vague term based on a systematic literature review. In: BMC Medical Ethics 14:55

Abstract

Background: Recently, individualized or personalized medicine (PM) has become a buzz word in the academic as well as public debate surrounding health care. However, PM lacks a clear definition and is open to interpretation. This conceptual vagueness complicates public discourse on chances, risks and limits of PM. Furthermore, stakeholders might use it to further their respective interests and preferences. For these reasons it is important to have a shared understanding of PM. In this paper, we present a sufficiently precise as well as adequate definition of PM with the potential of wide acceptance. Methods: For this purpose, in a first step a systematic literature review was conducted to understand how PM is actually used in scientific practice. PubMed was searched using the keywords "individualized medicine"

• Dokumententyp: Zeitschriftenartikel
• Publikationsform: Publisher's Version
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1472-6939
• Sprache: Englisch