TY - JOUR IS - 6 A1 - Gutekunst, R. A1 - Valesky, A. A1 - Borisch, B. A1 - Hafermann, W. A1 - Kiffner, E. A1 - Thies, E. A1 - L?hrs, U. A1 - Scriba, Peter Christian ID - epub8532 SN - 0021-972X AV - public Y1 - 1986/// JF - The journal of clinical endocrinology & metabolism N2 - Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH. In 25 patients, localization of enlarged parathyroid glands was successful. In 2 patients, the tumors were located retrosternally and, thus, could not be detected by ultrasound. One patient had a multinodular goiter which impeded localization. In 1 patient with renal osteodystrophy, 2 enlarged parathyroid glands in the neck were not visualized preoperatively. Cytology was not diagnostic, although some cytological features were suggestive of parathyroid cells. Immunostaining of the aspirated smears for PTH, however, correctly diagnosed all preoperatively localized lesions. Ultrasound should be the routine procedure of choice for preoperative localization of abnormal parathyroid glands in primary hyperparathyroidism. Fine needle aspiration and immunocytochemistry can supply confirmation, if necessary. TI - Parathyroid localization SP - 1390 EP - 1393 UR - https://epub.ub.uni-muenchen.de/8532/ ER -