Boshart, Michael and Nitsch, Doris and Schütz, Günther
Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms?
In: Trends in Genetics, Vol. 9, No. 7: pp. 240-245
Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell differentiation.