Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms?

Boshart, Michael and Nitsch, Doris and Schütz, Günther (1993): Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? In: Trends in Genetics, Vol. 9, No. 7: pp. 240-245

Abstract

Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell differentiation.

• Item Type: Article
• Collections: Biology
• Subjects: 500 Science > 570 Life sciences; biology