Synthesis of 13C—O-labelled tertiary alkanoic acids by the Koch-haaf-reaction

Langhals, Heinz and Mergelsberg, Ingrid and Rüchardt, Christoph (1981): Synthesis of 13C—O-labelled tertiary alkanoic acids by the Koch-haaf-reaction. In: Tetrahedron Letters, Vol. 22, No. 25: pp. 2365-2366

Abstract

Good yields of tertiary alkanoic acids are obtained from the Koch-Haaf-synthesis even when only stoichiometric amounts of carbinol and HCOOH are used. This offers a new approach to 13CO-labelled tertiary alkanoic acids. - An excess of HCOOH is generally used in the Koch-Haaf-synthesis1) of carboxylic acids from carbinols and HCOOH in conc. H2SO4.

• Item Type: Article
• Collections: Chemistry and Pharmacy
• Subjects: 500 Science > 540 Chemistry