Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla

Stanyon, Roscoe and Wienberg, Johannes and Romagno, D. and Bigoni, F. and Jauch, Anna and Cremer, Thomas (1992): Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla. In: American Journal of Physical Anthropology, Vol. 88, No. 2: pp. 245-250

Abstract

The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined with high-resolution banding, replication sequence analysis, and fluorochrome staining to demonstrate that a reciprocal translocation between ancestral chromosomes homologous to human chromosome 5 and 17 has indeed occurred. © 1992 Wiley-Liss, Inc.

• Item Type: Article
• Keywords: In situ hybridization, chromosome banding, phylogeny, primates
• Collections: Medicine
• Subjects: 600 Technology > 610 Medicine and health