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Anzahl der Publikationen: 35
Zeitschriftenartikel
Issels, Rolf D. 
ORCID: https://orcid.org/0000-0002-3494-6561; Böck, Stefan; Pelzer, Uwe; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Ghadjar, Pirus; Lindner, Lars H. ORCID: https://orcid.org/0000-0003-3708-8264; Albertsmeier, Markus ORCID: https://orcid.org/0000-0002-5028-5062; Angele, Martin K.; Schmidt, Michael ORCID: https://orcid.org/0000-0001-5898-9323; Xu, Yujun ORCID: https://orcid.org/0000-0002-8487-7584; Bahra, Marcus; Pratschke, Johann; Schoenberg, Michael; Thasler, Wolfgang E.; Salat, Christoph; Stoetzer, Oliver J.; Knoefel, Wolfram T.; Graf, Dirk; Wessalowski, Rüdiger; Keitel-Anselmino, Verena; Koenigsrainer, Alfred; Bitzer, Michael ORCID: https://orcid.org/0000-0002-4463-8263; Zips, Daniel; Bamberg, Michael; Fietkau, Rainer; Ott, Oliver; Kawecki, Maciej ORCID: https://orcid.org/0000-0001-7858-6214; Wyrwicz, Lucjan; Rutkowski, Piotr; Rentsch, Markus; Ababei, Juliana; Reichardt, Peter; Rigamonti, Marco; Weber, Bernhard; Abdel-Rahman, Sultan; Tschoep–Lechner, Katharina; Jauch, Karl-Walter; Bruns, Christiane J.; Oettle, Helmut; Bergwelt-Baildon, Michael von; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321 und Werner, Jens
(2023):
Regional hyperthermia with cisplatin added to gemcitabine versus gemcitabine in patients with resected pancreatic ductal adenocarcinoma: The HEAT randomised clinical trial.
In: European Journal of Cancer (EJC), Bd. 181: S. 155-165
ORCID: https://orcid.org/0000-0002-3494-6561; Böck, Stefan; Pelzer, Uwe; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Ghadjar, Pirus; Lindner, Lars H. ORCID: https://orcid.org/0000-0003-3708-8264; Albertsmeier, Markus ORCID: https://orcid.org/0000-0002-5028-5062; Angele, Martin K.; Schmidt, Michael ORCID: https://orcid.org/0000-0001-5898-9323; Xu, Yujun ORCID: https://orcid.org/0000-0002-8487-7584; Bahra, Marcus; Pratschke, Johann; Schoenberg, Michael; Thasler, Wolfgang E.; Salat, Christoph; Stoetzer, Oliver J.; Knoefel, Wolfram T.; Graf, Dirk; Wessalowski, Rüdiger; Keitel-Anselmino, Verena; Koenigsrainer, Alfred; Bitzer, Michael ORCID: https://orcid.org/0000-0002-4463-8263; Zips, Daniel; Bamberg, Michael; Fietkau, Rainer; Ott, Oliver; Kawecki, Maciej ORCID: https://orcid.org/0000-0001-7858-6214; Wyrwicz, Lucjan; Rutkowski, Piotr; Rentsch, Markus; Ababei, Juliana; Reichardt, Peter; Rigamonti, Marco; Weber, Bernhard; Abdel-Rahman, Sultan; Tschoep–Lechner, Katharina; Jauch, Karl-Walter; Bruns, Christiane J.; Oettle, Helmut; Bergwelt-Baildon, Michael von; Heinemann, Volker ORCID: https://orcid.org/0000-0002-1349-3321 und Werner, Jens
(2023):
Regional hyperthermia with cisplatin added to gemcitabine versus gemcitabine in patients with resected pancreatic ductal adenocarcinoma: The HEAT randomised clinical trial.
In: European Journal of Cancer (EJC), Bd. 181: S. 155-165
Lee, Lucas D.; Pozios, Ioannis; Liu, Verena; Nachbichler, Silke B.; Böhmer, Dirk; Kamphues, Carsten; Beyer, Katharina; Bruns, Christiane J.; Kreis, Martin E. und Seeliger, Hendrik
(2022):
Thymidine phosphorylase induction by ionizing radiation antagonizes 5-fluorouracil resistance in human ductal pancreatic adenocarcinoma.
In: Radiation and Environmental Biophysics, Bd. 61, Nr. 2: S. 255-262
Datta, Rabi R.; Schran, Simon; Persa, Oana-Diana; Aguilar, Claire; Thelen, Martin; Lehmann, Jonas; Garcia-Marquez, Maria A.; Wennhold, Kerstin; Preugszat, Ella; Zentis, Peter; Bergwelt-Baildon, Michael S. van; Quaas, Alexander; Bruns, Christiane J.; Kurschat, Christine; Mauch, Cornelia; Loeser, Heike; Stippel, Dirk L. und Schloesser, Hans A.
(2022):
Post-transplant Malignancies Show Reduced T-cell Abundance and Tertiary Lymphoid Structures as Correlates of Impaired Cancer Immunosurveillance.
In: Clinical Cancer Research, Bd. 28, Nr. 8: S. 1712-1723
Pozios, Ioannis; Hering, Nina A.; Günzler, Emily; Arndt, Marco; Elezkurtaj, Sefer; Knosel, Thomas; Bruns, Christiane J.; Margonis, Georgios A.; Beyer, Katharina und Seeliger, Hendrik
(2022):
Gp130 is expressed in pancreatic cancer and can be targeted by the small inhibitor molecule SC144.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 1: S. 271-280
Sun, Jialei; Zhou, Chenhao; Zhao, Yue; Zhang, Xiaofei; Chen, Wanyong; Zhou, Qiang; Hu, Bo; Gao, Dongmei; Raatz, Lisa; Wang, Zhefang; Nelson, Peter J.; Jiang, Yuchao; Ren, Ning; Bruns, Christiane J. und Zhou, Haijun
(2021):
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation.
In: Redox Biology, Bd. 41, 101942
Zhao, Yue; Li, Jiahui; Li, Dai; Wang, Zhefang; Zhao, Jiangang; Wu, Xiaolin; Sun, Qiye; Lin, Peter Ping; Plum, Patrick; Damanakis, Alexander; Gebauer, Florian; Zhou, Menglong; Zhang, Zhen; Schloesser, Hans; Jauch, Karl-Walter; Nelson, Peter J. und Bruns, Christiane J.
(2020):
Tumor biology and multidisciplinary strategies of oligometastasis in gastrointestinal cancers.
In: Seminars in Cancer Biology, Bd. 60: S. 334-343
Wang, Zhefang; Qin, Jie; Zhao, Jiangang; Li, Jiahui; Li, Dai; Popp, Marie; Popp, Felix; Alakus, Hakan; Kong, Bo; Dong, Qiongzhu; Nelson, Peter J.; Zhao, Yue und Bruns, Christiane J.
(2020):
Inflammatory IFIT3 renders chemotherapy resistance by regulating post-translational modification of VDAC2 in pancreatic cancer.
In: Theranostics, Bd. 10, Nr. 16: S. 7178-7192
Modest, Dominik Paul; Heinemann, Volker; Folprecht, Gunnar; Denecke, Timm; Pratschke, Johann; Lang, Hauke; Bemelmans, Marc; Becker, Thomas; Rentsch, Markus; Seehofer, Daniel; Bruns, Christiane J.; Gebauer, Bernhard; Held, Swantje; Stahler, Arndt; Heinrich, Kathrin; Einem, Jobst C. von; Stintzing, Sebastian; Neumann, Ulf P. und Ricard, Ingrid
(2020):
Factors That Influence Conversion to Resectability and Survival After Resection of Metastases in RAS WT Metastatic Colorectal Cancer (mCRC): Analysis of FIRE-3-AIOKRK0306.
In: Annals of Surgical Oncology, Bd. 27, Nr. 7: S. 2389-2401
Pozios, Ioannis; Seel, Nina N.; Hering, Nina A.; Hartmann, Lisa; Liu, Verena; Camaj, Peter; Müller, Mario H.; Lee, Lucas D.; Bruns, Christiane J.; Kreis, Martin E. und Seeliger, Hendrik
(2020):
Raloxifene inhibits pancreatic adenocarcinoma growth by interfering with ER beta and IL-6/gp130/STAT3 signaling.
In: Cellular Oncology, Bd. 44, Nr. 1: S. 167-177
Mahajan, Ujjwal M.; Goni, Elisabetta; Langhoff, Enno; Li, Qi; Costello, Eithne; Greenhalf, William; Kruger, Stephan; Ormanns, Steffen; Halloran, Christopher; Ganeh, Paula; Marron, Manuela; Laemmerhirt, Felix; Zhao, Yue; Beyer, Georg; Weiss, Frank-Ulrich; Sendler, Matthias; Bruns, Christiane J.; Kohlmann, Thomas; Kirchner, Thomas; Werner, Jens; D'Haese, Jan G.; Bergwelt, Michael von; Heinemann, Volker; Neoptolemos, John P.; Buechler, Markus W.; Belka, Claus; Boeck, Stefan; Lerch, Markus M. und Mayerle, Julia
(2020):
Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer.
In: Jnci Cancer Spectrum, Bd. 4, Nr. 1, pkz060
Schloesser, Hans A.; Thelen, Martin; Lechner, Axel; Wennhold, Kerstin; Garcia-Marquez, Maria A.; Rothschild, Sacha I.; Staib, Elena; Zander, Thomas; Beutner, Dirk; Gathof, Birgit; Gilles, Ramona; Cukuroglu, Engin; Goke, Jonathan; Shimabukuro-Vornhagen, Alexander; Drebber, Uta; Quaas, Alexander; Bruns, Christiane J.; Hoelscher, Arnulf H. und Bergwelt-Baildon, Michael von
(2019):
B cells in esophago-gastric adenocarcinoma are highly differentiated, organize in tertiary lymphoid structures and produce tumor-specific antibodies.
In: Oncoimmunology, Bd. 8, Nr. 1, e1512458
Pfeiler, Susanne; Thakur, Manovriti; Grünauer, Petra; Megens, Remco T. A.; Joshi, Urjita; Coletti, Raffaele; Samara, Verena; Müller-Stoy, Geraldine; Ishikawa-Ankerhold, Hellen; Stark, Konstantin; Klingl, Andreas; Fröhlich, Thomas; Arnold, Georg J.; Woermann, Sonja; Bruns, Christiane J.; Alguel, Hana; Weber, Christian; Massberg, Steffen und Engelmann, Bernd
(2019):
CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis.
In: Faseb Journal, Bd. 33, Nr. 2: S. 1860-1872
Zhao, Jiangang; Schlosser, Hans A.; Wang, Zhefang; Qin, Jie; Li, Jiahui; Popp, Felix; Popp, Marie Christine; Alakus, Hakan; Chon, Seung-Hun; Hansen, Hinrich P.; Neiss, Wolfram E.; Jauch, Karl-Walter; Bruns, Christiane J. und Zhao, Yue
(2019):
Tumor-Derived Extracellular Vesicles Inhibit Natural Killer Cell Function in Pancreatic Cancer.
In: Cancers, Bd. 11, Nr. 6, 874
Stark, Konstantin; Schubert, Irene; Joshi, Urjita; Kilani, Badr; Hoseinpour, Parandis; Thakur, Manovriti; Grünauer, Petra; Pfeiler, Susanne; Schmidergall, Tobias; Stockhausen, Sven; Bäumer, Markus; Chandraratne, Sue; Brühl, Marie Luise von; Lorenz, Michael; Coletti, Raffaele; Reese, Sven ORCID: https://orcid.org/0000-0002-4605-9791; Laitinen, Ilina; Wörmann, Sonja Maria; Algül, Hana; Bruns, Christiane J.; Ware, Jerry; Mackman, Nigel; Engelmann, Bernd und Massberg, Steffen
(Februar 2018):
Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo.
In: Arteriosclerosis, thrombosis, and vascular biology, Bd. 38, Nr. 4: S. 772-786
[PDF, 7kB]
ORCID: https://orcid.org/0000-0002-4605-9791; Laitinen, Ilina; Wörmann, Sonja Maria; Algül, Hana; Bruns, Christiane J.; Ware, Jerry; Mackman, Nigel; Engelmann, Bernd und Massberg, Steffen
(Februar 2018):
Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo.
In: Arteriosclerosis, thrombosis, and vascular biology, Bd. 38, Nr. 4: S. 772-786
[PDF, 7kB]
Bösch, Florian; Bruns, Christiane J.; Guba, Markus; Werner, Jens; Angele, Martin K.; Hofmann, Katharina; Coenen, Michaela; Pratschke, Sebastian; Thomas, Michael und Knösel, Thomas
(2018):
Surgical treatment of pNET - Experience of a \textquotedblhigh-volume\textquotedbl center.
In: Surgical Oncology, Bd. 27, Nr. 3: S. 409-414
Modest, Dominik P.; Denecke, Timm; Pratschke, J.; Ricard, Ingrid; Lang, H.; Bemelmans, M.; Becker, T.; Rentsch, Markus; Seehofer, Daniel; Bruns, Christiane J.; Gebauer, B.; Modest, H. I.; Held, S.; Folprecht, Gunnar; Heinemann, Volker und Neumann, Ulf Peter
(2018):
Surgical treatment options following chemotherapy plus cetuximab or bevacizumab in metastatic colorectal cancer-central evaluation of FIRE-3.
In: European Journal of Cancer (EJC), Bd. 88: S. 77-86
Seeliger, Hendrik; Pozios, Ioannis; Assmann, Gerald; Zhao, Yue; Müller, Mario H.; Knoesel, Thomas; Kreis, Martin E. und Bruns, Christiane J.
(2018):
Expression of estrogen receptor beta correlates with adverse prognosis in resected pancreatic adenocarcinoma.
In: BMC Cancer
18:1049
[PDF, 1MB]
Pozios, Ioannis; Knoesel, Thomas; Zhao, Yue; Assmann, Gerald; Pozios, Iraklis; Müller, Mario H.; Bruns, Christiane J.; Kreis, Martin E. und Seeliger, Hendrik
(2018):
Expression of phosphorylated estrogen receptor beta is an independent negative prognostic factor for pancreatic ductal adenocarcinoma.
In: Journal of Cancer Research and Clinical Oncology, Bd. 144, Nr. 10: S. 1887-1897
Renz, Bernhard W.; Khalil, Philippe N.; Mikhailov, Michael; Graf, Sandra; Schiergens, Tobias S.; Niess, Hanno; Boeck, Stefan; Heinemann, Volker; Hartwig, Werner; Werner, Jens; Bruns, Christiane J. und Kleespies, Axel
(2016):
Pancreaticoduodenectomy for adenocarcinoma of the pancreatic head is justified in elderly patients: A Retrospective Cohort Study.
In: International Journal of Surgery, Bd. 28: S. 118-125
Wang, Yan; Zhao, Yue; Herbst, Andreas; Kalinski, Thomas; Qin, Jiwei; Wang, Xiaoyan; Jiang, Zhenzhong; Benedix, Frank; Franke, Sabine; Wartman, Thomas; Camaj, Peter; Halangk, Walter; Kolligs, FrankT.; Jauch, Karl W.; Nelson, Peter J. und Bruns, Christiane J.
(2016):
miR-221 Mediates Chemoresistance of Esophageal Adenocarcinoma by Direct Targeting of DKK2 Expression.
In: Annals of Surgery, Bd. 264, Nr. 5: S. 804-814
[PDF, 1MB]
Hagenhoff, Anna; Bruns, Christiane J.; Zhao, Yue; Lüttichau, Irene von; Niess, Hanno; Spitzweg, Christine und Nelson, Peter J.
(2016):
Harnessing mesenchymal stem cell homing as an anticancer therapy.
In: Expert Opinion On Biological therapy, Bd. 16, Nr. 9: S. 1079-1092
Klein, Brianna J.; Wang, Xiaoyan; Cui, Gaofeng; Yuan, Chao; Botuyan, Maria Victoria; Lin, Kevin; Lu, Yue; Wang, Xiaolu; Zhao, Yue; Bruns, Christiane J.; Mer, Georges; Shi, Xiaobing und Kutateladze, Tatiana G.
(2016):
PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation.
In: Cell Reports, Bd. 17, Nr. 4: S. 1158-1170
[PDF, 10MB]
Gamba, Sebastian; Camaj, Peter; Heinemann, Volker; Laubender, Rüdiger P.; Wang, Yan; Zhao, Yue; Stintzing, Sebastian; Giessen, Clemens; Boeck, Stefan; Haertl, Christoph; Bruns, Christiane J. und Modest, Dominik P.
(2015):
Effect of KRAS exon 2 mutations on antitumor activity of afatinib and gefitinib.
In: Anti-Cancer Drugs, Bd. 26, Nr. 4: S. 371-378
[PDF, 251kB]
Niess, Hanno; Einem, Jobst C. von; Thomas, Michael N.; Michl, Marlies; Angele, Martin K.; Huss, Ralf; Günther, Christine; Nelson, Peter J.; Bruns, Christiane J. und Heinemann, Volker
(2015):
Treatment of advanced gastrointestinal tumors with genetically modified autologous mesenchymal stromal cells (TREAT-ME1): study protocol of a phase I/II clinical trial.
In: BMC Cancer
15:237
[PDF, 1MB]
Angele, Martin K.; Albertsmeier, Markus; Prix, Niclas; Hohenberger, Peter; Abdel-Rahman, Sultan; Dieterle, Nelli; Schmidt, Michael; Mansmann, Ulrich; Bruns, Christiane J.; Issels, Rolf D.; Jauch, Karl-Walter und Lindner, Lars H.
(2014):
Effectiveness of Regional Hyperthermia With Chemotherapy for High-Risk Retroperitoneal and Abdominal Soft-Tissue Sarcoma After Complete Surgical Resection. A Subgroup Analysis of a Randomized Phase-III Multicenter Study.
In: Annals of Surgery, Bd. 260, Nr. 5: S. 749-756
[PDF, 294kB]
Joka, Mareile; Boeck, Stefan; Zech, Christoph J.; Seufferlein, Thomas; Wichert, Götz von; Licht, Thomas; Krause, Annekatrin; Jauch, Karl-Walter; Heinemann, Volker und Bruns, Christiane J.
(2014):
Combination of antiangiogenic therapy using the mTOR-inhibitor everolimus and low-dose chemotherapy for locally advanced and/or metastatic pancreatic cancer: a dose-finding study.
In: Anti-Cancer Drugs, Bd. 25, Nr. 9: S. 1095-1101
[PDF, 364kB]
Zhao, L.; Zhao, Y.; Bao, Q.; Niess, H.; Jauch, Karl-Walter und Bruns, Christiane J.
(2012):
Clinical Implication of Targeting of Cancer Stem Cells.
In: European Surgical Research, Nr. 1: S. 8-15
[PDF, 159kB]
Khalil, Philipe N.; Kleespies, Axel; Rentsch, Markus; Thasler, Wolfgang E.; Jauch, Karl-Walter und Bruns, Christiane J.
(2010):
Description and evaluation of a bench porcine model for teaching surgical residents vascular anastomosis skills.
In: BMC Research Notes
3:189
[PDF, 655kB]
Rothmeier, Andrea S.; Ischenko, Ivan; Joore, Jos; Garczarczyk, Dorota; Fürst, Robert; Bruns, Christiane J.; Vollmar, Angelika M. und Zahler, Stefan
(2009):
Investigation of the marine compound spongistatin 1 links the inhibition of PKCα translocation to nonmitotic effects of tubulin antagonism in angiogenesis.
In: The FASEB journal, Bd. 23, Nr. 4: S. 1127-1137
[PDF, 923kB]
Camaj, Peter; Seeliger, Hendrik; Ischenko, Ivan; Krebs, Stefan; Blum, Helmut; De Toni, Enrico N.; Faktorova, Dagmar; Jauch, Karl-Walter und Bruns, Christiane J.
(2009):
EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells.
In: Biological Chemistry, Bd. 390, Nr. 12: S. 1293-1302
[PDF, 218kB]
Boeck, Stefan; Bruns, Christiane J.; Sargent, Mirja; Schäfer, Claus; Seufferlein, Thomas; Jauch, Karl-Walter und Heinemann, Volker
(2009):
Current Oncological Treatment of Patients with Pancreatic Cancer in Germany: Results from a National Survey on behalf of the Arbeitsgemeinschaft Internistische Onkologie and the Chirurgische Arbeitsgemeinschaft Onkologie of the Germany Cancer Society.
In: Oncology, Nr. 1: S. 40-48
[PDF, 306kB]
Walz, Christian; Zedler, Siegfried; Schneider, Christian P.; Albertsmeier, Markus; Loehe, Florian; Bruns, Christiane J.; Faist, Eugen; Chaudry, Irshad H. und Angele, Martin K.
(2009):
The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage.
In: Innate Immunity, Bd. 15, Nr. 4: S. 233-241
[PDF, 194kB]
Conrad, Claudius; Niess, Hanno; Jauch, Karl-Walter; Bruns, Christiane J.; Hartl, Wolfgang H. und Welker, Lorenz
(2007):
Overture for growth hormone: Requiem for interleukin-6?
In: Critical Care Medicine, Bd. 35, Nr. 12: S. 2709-2713
Boeck, Stefan; Wilkowski, Ralf; Bruns, Christiane J.; Issels, Rolf-Dieter; Schulz, Christoph; Moosmann, Nicolas; Laessig, Dorit; Haas, Michael; Golf, Alexander und Heinemann, Volker
(2007):
Oral capecitabine in gemcitabine-pretreated patients with advanced pancreatic cancer.
In: Oncology, Nr. 3-4: S. 221-227
[PDF, 330kB]
Kleespies, A.; Bruns, Christiane J. und Jauch, Karl-Walter
(2005):
Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies.
In: Onkologie, Nr. 5: S. 281-288
[PDF, 70kB]