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Anzahl der Publikationen: 15
Zeitschriftenartikel
Stock, Sophia 
ORCID: https://orcid.org/0000-0002-5072-5013; Benmebarek, Mohamed-Reda ORCID: https://orcid.org/0000-0002-1201-7067; Kluever, Anna-Kristina ORCID: https://orcid.org/0000-0001-6246-6082; Darowski, Diana ORCID: https://orcid.org/0000-0002-8778-7920; Jost, Christian ORCID: https://orcid.org/0000-0002-4169-5879; Stubenrauch, Kay-Gunnar; Benz, Joerg; Freimoser-Grundschober, Anne ORCID: https://orcid.org/0000-0001-5715-3639; Moessner, Ekkehard; Umana, Pablo; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.
In: Journal for ImmunoTherapy of Cancer, Bd. 10, Nr. 7, e005054
[PDF, 17MB]
ORCID: https://orcid.org/0000-0002-5072-5013; Benmebarek, Mohamed-Reda ORCID: https://orcid.org/0000-0002-1201-7067; Kluever, Anna-Kristina ORCID: https://orcid.org/0000-0001-6246-6082; Darowski, Diana ORCID: https://orcid.org/0000-0002-8778-7920; Jost, Christian ORCID: https://orcid.org/0000-0002-4169-5879; Stubenrauch, Kay-Gunnar; Benz, Joerg; Freimoser-Grundschober, Anne ORCID: https://orcid.org/0000-0001-5715-3639; Moessner, Ekkehard; Umana, Pablo; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.
In: Journal for ImmunoTherapy of Cancer, Bd. 10, Nr. 7, e005054
[PDF, 17MB]
Dickopf, Steffen; Buldun, Can; Vasic, Vedran; Georges, Guy; Hage, Carina; Mayer, Klaus; Forster, Matthias; Wessels, Uwe; Stubenrauch, Kay-Gunnar; Benz, Jörg; Ehler, Andreas; Lauer, Matthias E.; Ringler, Philippe; Kobold, Sebastian; Endres, Stefan; Klein, Christian und Brinkmann, Ulrich
(2022):
Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies.
In: Biological Chemistry, Bd. 403, Nr. 5-6: S. 495-508
Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35: S. 2243-2257
[PDF, 5MB]
ORCID: https://orcid.org/0000-0001-7594-7280; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35: S. 2243-2257
[PDF, 5MB]
Augsberger, Christian; Hanel, Gerulf; Xu, Wei; Pulko, Vesna; Hanisch, Lydia Jasmin; Augustin, Angelique; Challier, John; Hunt, Katharina; Vick, Binje; Rovatti, Pier Eduardo; Krupka, Christina; Rothe, Maurine; Schonle, Anne; Sam, Johannes; Lezan, Emmanuelle; Ducret, Axel; Ortiz-Franyuti, Daniela; Walz, Antje-Christine; Benz, Jorg; Bujotzek, Alexander; Lichtenegger, Felix S.; Gassner, Christian; Carpy, Alejandro; Lyamichev, Victor; Patel, Jigar; Konstandin, Nikola; Tunger, Antje; Schmitz, Marc; Bergwelt-Baildon, Michael von; Spiekermann, Karsten; Vago, Luca; Jeremias, Irmela; Marrer-Berger, Estelle; Umana, Pablo; Klein, Christian und Subklewe, Marion
(2021):
Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody.
In: Blood, Bd. 138, Nr. 25: S. 2655-2669
Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter und Kobold, Sebastian
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35, Nr. 8: S. 2243-2257
Strefford, Jonathan C.; Nowicka, Malgorzata; Hargreaves, Chantal E.; Burton, Cathy; Davies, Andrew; Ganderton, Rosalind; Hiddemann, Wolfgang; Iriyama, Chisako; Klapper, Wolfram; Latham, Kate V.; Martelli, Maurizio; Mir, Farheen; Parker, Helen; Potter, Kathleen N.; Rose-Zerilli, Matthew J. J.; Sehn, Laurie H.; Trneny, Marek; Vitolo, Umberto; Bolen, Christopher R.; Klein, Christian; Knapp, Andrea; Oestergaard, Mikkel Z. und Cragg, Mark S.
(2021):
Single-nucleotide Fc gamma receptor polymorphisms do not impact obinutuzumab/rituximab outcome in patients with lymphoma.
In: Blood Advances, Bd. 5, Nr. 15: S. 2935-2944
Geiger, Martina; Stubenrauch, Kay-Gunnar; Sam, Johannes; Richter, Wolfgang F.; Jordan, Gregor; Eckmann, Jan; Hage, Carina; Nicolini, Valeria; Freimoser-Grundschober, Anne; Ritter, Mirko; Lauer, Matthias E.; Stahlberg, Henning; Ringler, Philippe; Patel, Jigar; Sullivan, Eric; Grau-Richards, Sandra; Endres, Stefan; Kobold, Sebastian; Umana, Pablo; Bruenker, Peter und Klein, Christian
(2020):
Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody.
In: Nature Communications, Bd. 11, Nr. 1, 3196
[PDF, 3MB]
Karches, Clara H.; Benmebarek, Mohamed-Reda; Schmidbauer, Moritz L.; Kurzay, Mathias; Klaus, Richard; Geiger, Martina; Rataj, Felicitas; Cadilha, Bruno L.; Lesch, Stefanie; Heise, Constanze; Murr, Ramona; vom Berg, Johannes; Jastroch, Martin; Lamp, Daniel; Ding, Jian; Duewell, Peter; Niederfellner, Gerhard; Sustmann, Claudio; Endres, Stefan; Klein, Christian und Kobold, Sebastian
(2019):
Bispecific Antibodies Enable Synthetic Agonistic Receptor-Transduced T Cells for Tumor Immunotherapy.
In: Clinical Cancer Research, Bd. 25, Nr. 19: S. 5890-5900
Darowski, Diana; Jost, Christian; Stubenrauch, Kay; Wessels, Uwe; Benz, Jörg; Ehler, Andreas; Freimoser-Grundschober, Anne; Bruenker, Peter; Moessner, Ekkehard; Umana, Pablo; Kobold, Sebastian und Klein, Christian
(2019):
P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation.
In: Protein Engineering Design & Selection, Bd. 32, Nr. 5: S. 207-218
Darowski, Diana; Kobold, Sebastian; Jost, Christian und Klein, Christian
(2019):
Combining the best of two worlds: highly flexible chimeric antigen receptor adaptor molecules (CAR-adaptors) for the recruitment of chimeric antigen receptor T cells.
In: Mabs, Bd. 11, Nr. 4: S. 621-631
Rataj, Felicitas; Jacobi, Severin J.; Stoiber, Stefan; Asang, Florian; Ogonek, Justyna; Tokarew, Nicholas; Cadilha, Bruno L.; van Puijenbroek, Erwin; Heise, Constanze; Duewell, Peter; Endres, Stefan; Klein, Christian und Kobold, Sebastian
(2019):
High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy.
In: British Journal of Cancer, Bd. 120, Nr. 1: S. 79-87
Klanova, Magdalena; Oestergaard, Mikkel Z.; Trneny, Marek; Hiddemann, Wolfgang; Marcus, Robert; Sehn, Laurie H.; Vitolo, Umberto; Bazeos, Alexandra; Goede, Valentin; Zeuner, Harald; Knapp, Andrea; Sahin, Deniz; Spielewoy, Nathalie; Bolen, Christopher R.; Cardona, Andres; Klein, Christian; Venstrom, Jeffrey M.; Nielsen, Tina und Fingerle-Rowson, Guenter
(2019):
Prognostic Impact of Natural Killer Cell Count in Follicular Lymphoma and Diffuse Large B-cell Lymphoma Patients Treated with Immunochemotherapy.
In: Clinical Cancer Research, Bd. 25, Nr. 15: S. 4634-4643
Sustmann, Claudio; Dickopf, Steffen; Regula, Jörg T.; Kettenberger, Hubert; Molhoj, Michael; Gassner, Christian; Weininger, Diana; Fenn, Sebastian; Manigold, Tobias; Kling, Lothar; Kuenkele, Klaus-Peter; Schwaiger, Manfred; Bossenmaier, Birgit; Griese, Julia J.; Hopfner, Karl-Peter; Graff-Meyer, Alexandra; Stahlberg, Henning; Ringler, Philippe; Lauer, Matthias E.; Brinkmann, Ulrich; Schäfer, Wolfgang und Klein, Christian
(2019):
DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity.
In: Mabs, Bd. 11, Nr. 8: S. 1402-1414
Castoldi, Raffaella; Schanzer, Jürgen; Panke, Christian; Jucknischke, Ute; Neubert, Natalie J.; Croasdale, Rebecca; Scheuer, Werner; Auer, Johannes; Klein, Christian; Niederfellner, Gerhard; Kobold, Sebastian und Sustmann, Claudio
(2016):
TetraMabs: simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations.
In: Protein Engineering Design & Selection, Bd. 29, Nr. 10: S. 467-475
Fenn, Sebastian; Schiller, Christian B.; Griese, Julia J.; Duerr, Harald; Imhof-Jung, Sabine; Gassner, Christian; Moelleken, Joerg; Regula, Joerg Thomas; Schaefer, Wolfgang; Thomas, Markus; Klein, Christian; Hopfner, Karl-Peter und Kettenberger, Hubert
(2013):
Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
In: PLOS ONE 8(4), e61953 [PDF, 2MB]
In: PLOS ONE 8(4), e61953 [PDF, 2MB]