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Anzahl der Publikationen: 32
Zeitschriftenartikel
Groll, Tanja; Silva, Miguel; Sarker, Rim Sabrina Jahan; Tschurtschenthaler, Markus; Schnalzger, Theresa; Mogler, Carolin; Denk, Daniela; Schoelch, Sebastian; Schraml, Barbara U.; Ruland, Jürgen; Rad, Roland; Saur, Dieter; Weichert, Wilko; Jesinghaus, Moritz; Matiasek, Kaspar und Steiger, Katja
(2022):
Comparative Study of the Role of Interepithelial Mucosal Mast Cells in the Context of Intestinal Adenoma-Carcinoma Progression.
In: Cancers, Bd. 14, Nr. 9, 2248
Kuhn, Laura B.; Valentin, Stefanie; Stojanovic, Kristina; Strobl, Daniel C.; Babushku, Tea; Wang, Yan; Rambold, Ursula; Scheffler, Laura; Grath, Sonja; John-Robbert, Dorothy; Blum, Helmut; Feuchtinger, Annette; Blutke, Andreas; Weih, Falk; Kitamura, Daisuke; Rad, Roland; Strobl, Lothar J. und Zimber-Strobl, Ursula
(2022):
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.
In: Frontiers in Immunology, Bd. 13, 913275
Boos, Sophie L.; Loevenich, Leon P.; Vosberg, Sebastian; Engleitner, Thomas; Öllinger, Rupert; Kumbrink, Joerg; Rokavec, Matjaz; Michl, Marlies; Greif, Philipp A.; Jung, Andreas; Hermeking, Heiko; Neumann, Jens; Kirchner, Thomas; Rad, Roland und Jung, Peter
(2022):
Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.
In: Cellular and Molecular Gastroenterology and Hepatology, Bd. 13, Nr. 2: S. 517-540
Metzger, Rebecca; Winter, Lis; Bouznad, Nassim; Garzetti, Debora; Armansperg, Benedikt von; Rokavec, Matjaz; Lutz, Konstantin; Schafer, Yvonne; Krebs, Sabrina; Winheim, Elena; Friedrich, Verena; Matzek, Dana; Oellinger, Rupert; Rad, Roland; Stecher, Barbel; Hermeking, Heiko; Brocker, Thomas und Krug, Anne B.
(2022):
CCL17 Promotes Colitis-Associated Tumorigenesis Dependent on the Microbiota.
In: Journal of Immunology, Bd. 209, Nr. 11: S. 2227-2238
Braun, Christian J.; Adames, Andres Carbonell; Saur, Dieter und Rad, Roland
(2022):
Tutorial: design and execution of CRISPR in vivo screens.
In: Nature Protocols, Bd. 17, Nr. 9: S. 1903-1925
Sipol, Alexandra; Hameister, Erik; Xue, Busheng; Hofstetter, Julia; Barenboim, Maxim; Oellinger, Rupert; Jain, Gaurav; Prexler, Carolin; Rubio, Rebeca Alba; Baldauf, Michaela C.; Franchina, Davide G.; Petry, Andreas; Schmaeh, Juliane; Thiel, Uwe; Goerlach, Agnes; Cario, Gunnar; Brenner, Dirk; Richter, Guenther H. S.; Gruenewald, Thomas G. P.; Rad, Roland; Wolf, Elmar; Ruland, Juergen; Sorensen, Poul H. und Burdach, Stefan E. G.
(2022):
MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress.
In: Blood, Bd. 139, Nr. 8: S. 1184-1197
Kaltenbacher, Thorsten; Löprich, Jessica; Maresch, Roman; Weber, Julia; Müller, Sebastian; Oellinger, Rupert; Gross, Nina; Griger, Joscha; Andrade Krätzig, Niklas de; Avramopoulos, Petros; Ramanujam, Deepak; Brummer, Sabine; Widholz, Sebastian A.; Bärthel, Stefanie; Falcomata, Chiara; Pfaus, Anja; Alnatsha, Ahmed; Mayerle, Julia; Schmidt-Supprian, Marc; Reichert, Maximilian; Schneider, Günter; Ehmer, Ursula; Braun, Christian J.; Saur, Dieter; Engelhardt, Stefan und Rad, Roland
(2022):
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver.
In: Nature Protocols, Bd. 17, Nr. 4: S. 1142-1188
Falcomata, Chiara; Baerthel, Stefanie; Widholz, Sebastian A.; Schneeweis, Christian; Montero, Juan Jose; Toska, Albulena; Mir, Jonas; Kaltenbacher, Thorsten; Heetmeyer, Jeannine; Swietlik, Jonathan J.; Cheng, Jing-Yuan; Teodorescu, Bianca; Reichert, Oliver; Schmitt, Constantin; Grabichler, Kathrin; Coluccio, Andrea; Boniolo, Fabio; Veltkamp, Christian; Zukowska, Magdalena; Vargas, Angelica Arenas; Paik, Woo Hyun; Jesinghaus, Moritz; Steiger, Katja; Maresch, Roman; Oellinger, Rupert; Ammon, Tim; Baranov, Olga; Robles, Maria S.; Rechenberger, Julia; Kuster, Bernhard; Meissner, Felix; Reichert, Maximilian; Flossdorf, Michael; Rad, Roland; Schmidt-Supprian, Marc; Schneider, Guenter und Saur, Dieter
(2022):
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
In: Nature Cancer, Bd. 3, Nr. 3: S. 318-336
Mahajan, Ujjwal M.; Oehrle, Bettina; Sirtl, Simon; Alnatsha, Ahmed; Goni, Elisabetta; Regel, Ivonne; Beyer, Georg; Vornhuelz, Marlies; Vielhauer, Jakob; Chromik, Ansgar; Bahra, Markus; Klein, Fritz; Uhl, Waldemar; Fahlbusch, Tim; Distler, Marius; Weitz, Juergen; Gruetzmann, Robert; Pilarsky, Christian; Weiss, Frank Ulrich; Adam, M. Gordian; Neoptolemos, John P.; Kalthoff, Holger; Rad, Roland; Christiansen, Nicole; Bethan, Bianca; Kamlage, Beate; Lerch, Markus M. und Mayerle, Julia
(2022):
Independent Validation and Assay Standardization of Improved Metabolic Biomarker Signature to Differentiate Pancreatic Ductal Adenocarcinoma From Chronic Pancreatitis.
In: Gastroenterology, Bd. 163, Nr. 5: S. 1407-1422
Krauss, Lukas; Urban, Bettina C.; Hastreiter, Sieglinde; Schneider, Carolin; Wenzel, Patrick; Hassan, Zonera; Wirth, Matthias; Lankes, Katharina; Terrasi, Andrea; Klement, Christine; Cernilogar, Filippo M.; Öllinger, Rupert; Andrade Krätzig, Niklas de; Engleitner, Thomas; Schmid, Roland M.; Steiger, Katja; Rad, Roland; Krämer, Oliver H.; Reichert, Maximilian; Schotta, Gunnar; Saur, Dieter und Schneider, Günter
(2022):
HDAC2 Facilitates Pancreatic Cancer Metastasis.
In: Cancer Research, Bd. 82, Nr. 4: S. 695-707
Orben, Felix; Lankes, Katharina; Schneeweis, Christian; Hassan, Zonera; Jakubowsky, Hannah; Krauss, Lukas; Boniolo, Fabio; Schneider, Carolin; Schaefer, Arlett; Murr, Janine; Schlag, Christoph; Kong, Bo; Oellinger, Rupert; Wang, Chengdong; Beyer, Georg; Mahajan, Ujjwal M.; Xue, Yonggan; Mayerle, Julia; Schmid, Roland M.; Kuster, Bernhard; Rad, Roland; Braun, Christian J.; Wirth, Matthias; Reichert, Maximilian; Saur, Dieter und Schneider, Guenter
(2022):
Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype.
In: Jci Insight, Bd. 7, Nr. 10, 151353
Bozoglu, Tarik; Lee, Seungmin; Ziegler, Tilman; Jurisch, Victoria; Maas, Sanne; Baehr, Andrea; Hinkel, Rabea; Hoenig, Amelie; Hariharan, Anjana; Kim, Christina Inyeop; Decker, Simon; Sami, Haider; Koppara, Tobias; Oellinger, Ruppert; Müller, Oliver J.; Frank, Derk; Megens, Remco; Nelson, Peter; Weber, Christian; Schnieke, Angelika; Sperandio, Markus; Santamaria, Gianluca; Rad, Roland; Moretti, Alessandra; Laugwitz, Karl-Ludwig; Soehnlein, Oliver; Ogris, Manfred und Kupatt, Christian
(2022):
Endothelial Retargeting of AAV9 In Vivo.
In: Advanced Science, Bd. 9, Nr. 7, 2103867
Paulmann, Carmen; Spallek, Ria; Karpiuk, Oleksandra; Heider, Michael; Schäffer, Isabell; Zecha, Jana; Klaeger, Susan; Walzik, Michaela; Öllinger, Rupert; Engleitner, Thomas; Wirth, Matthias; Keller, Ulrich; Krönke, Jan; Rudelius, Martina; Kossatz, Susanne; Rad, Roland; Kuster, Bernhard und Bassermann, Florian
(2022):
The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
In: EMBO Journal, Bd. 41, Nr. 20, e110871
Chu, Chang-Feng; Sabath, Florian; Fibi-Smetana, Silvia; Sun, Shan; Oellinger, Rupert; Noessner, Elfriede; Chao, Ying-Yin; Rinke, Linus; Winheim, Elena; Rad, Roland; Krug, Anne B.; Taher, Leila und Zielinski, Christina E.
(19. August 2021):
Convalescent COVID-19 Patients Without Comorbidities Display Similar Immunophenotypes Over Time Despite Divergent Disease Severities.
In: Frontiers in Immunology, Bd. 12
[PDF, 13MB]
Corradini, Stefanie; Niyazi, Maximilian; Verellen, Dirk; Valentini, Vincenzo; Walsh, Sean; Grosu, Anca-L.; Lauber, Kirsten; Giaccia, Amato; Unger, Kristian; Debus, Jürgen; Pieters, Bradley R.; Guckenberger, Matthias; Senan, Suresh; Budach, Wilfried; Rad, Roland; Mayerle, Julia und Belka, Claus
(2021):
X-change symposium: status and future of modern radiation oncology-from technology to biology.
In: Radiation Oncology, Bd. 16, Nr. 1, 27
Hiltensperger, Michael; Beltran, Eduardo; Kant, Ravi; Tyystjarvi, Sofia; Lepennetier, Gildas; Moreno, Helena Dominguez; Bauer, Isabel J.; Grassmann, Simon; Jarosch, Sebastian; Schober, Kilian; Buchholz, Veit R.; Kenet, Selin; Gasperi, Christiane; Ollinger, Rupert; Rad, Roland; Muschaweckh, Andreas; Sie, Christopher; Aly, Lilian; Knier, Benjamin; Garg, Garima; Afzali, Ali M.; Gerdes, Lisa Ann; Kumpfel, Tania; Franzenburg, Soren; Kawakami, Naoto; Hemmer, Bernhard; Busch, Dirk H.; Misgeld, Thomas; Dornmair, Klaus und Korn, Thomas
(2021):
Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity.
In: Nature Immunology, Bd. 22, Nr. 7: S. 880-892
Ecker, Veronika; Stumpf, Martina; Brandmeier, Lisa; Neumayer, Tanja; Pfeuffer, Lisa; Engleitner, Thomas; Ringshausen, Ingo; Nelson, Nina; Juecker, Manfred; Wanninger, Stefan; Zenz, Thorsten; Wendtner, Clemens; Manske, Katrin; Steiger, Katja; Rad, Roland; Mueschen, Markus; Ruland, Jürgen und Buchner, Maike
(2021):
Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia.
In: Nature Communications, Bd. 12, Nr. 1, 3526
Bortoluzzi, Sabrina; Dashtsoodol, Nyambayar; Engleitner, Thomas; Drees, Christoph; Helmrath, Sabine; Mir, Jonas; Toska, Albulena; Flossdorf, Michael; Oellinger, Rupert; Solovey, Maria; Colome-Tatche, Maria; Kalfaoglu, Bahire; Ono, Masahiro; Buch, Thorsten; Ammon, Tim; Rad, Roland und Schmidt-Supprian, Marc
(2021):
Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling.
In: Immunity, Bd. 54, Nr. 11: S. 2497-2513
Arnold, Frank; Mahaddalkar, Pallavi U.; Kraus, Johann M.; Zhong, Xiaowei; Bergmann, Wendy; Srinivasan, Dharini; Gout, Johann; Roger, Elodie; Beutel, Alica K.; Zizer, Eugen; Tharehalli, Umesh; Daiss, Nora; Russell, Ronan; Perkhofer, Lukas; Oellinger, Rupert; Lin, Qiong; Azoitei, Ninel; Weiss, Frank-Ulrich; Lerch, Markus M.; Liebau, Stefan; Katz, Sarah-Fee; Lechel, Andre; Rad, Roland; Seufferlein, Thomas; Kestler, Hans A.; Ott, Michael; Sharma, Amar Deep; Hermann, Patrick C. und Kleger, Alexander
(2021):
Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration.
In: Advanced Science, Bd. 8, Nr. 14, 2100626
Kober-Hasslacher, Maike; Oh-Strauss, Hyunju; Kumar, Dilip; Soberon, Valeria; Diehl, Carina; Lech, Maciej; Engleitner, Thomas; Katab, Eslam; Fernandez-Saiz, Jvanesa; Piontek, Guido; Li, Hongwei; Menze, Bjorn; Ziegenhain, Christoph; Enard, Wolfgang; Rad, Roland; Boettcher, Jan P.; Anders, Hans-Joachim; Rudelius, Martina und Schmidt-Supprian, Marc
(2020):
c-Rel gain in B cells drives germinal center reactions and autoantibody production.
In: Journal of Clinical Investigation, Bd. 130, Nr. 6: S. 3270-3286
Weber, Julia; Braun, Christian J.; Saur, Dieter und Rad, Roland
(2020):
In vivo functional screening for systems-level integrative cancer genomics.
In: Nature Reviews Cancer, Bd. 20, Nr. 10: S. 573-593
Hidalgo-Sastre, Ana; Lubeseder-Martellato, Clara; Engleitner, Thomas; Steiger, Katja; Zhong, Suyang; Desztics, Judit; Öllinger, Rupert; Rad, Roland; Schmid, Roland M.; Hermeking, Heiko; Siveke, Jens T. und Figura, Guido von
(2020):
Mir34a constrains pancreatic carcinogenesis.
In: Scientific Reports, Bd. 10, Nr. 1, 9654
[PDF, 4MB]
Müller, Sebastian; Lange, Sebastian; Collins, Katharina A. N.; Krebs, Stefan; Blum, Helmut; Schneider, Guenter; Rad, Lena; Saur, Dieter und Rad, Roland
(2020):
Linkage of genetic drivers and strain-specific germline variants confound mouse cancer genome analyses.
In: Nature Communications, Bd. 11, Nr. 1, 4474
[PDF, 921kB]
Garg, Garima; Muschaweckh, Andreas; Moreno, Helena; Vasanthakumar, Ajithkumar; Floess, Stefan; Lepennetier, Gildas; Oellinger, Rupert; Zhan, Yifan; Regen, Tommy; Hiltensperger, Michael; Peter, Christian; Aly, Lilian; Knier, Benjamin; Palam, Lakshmi Reddy; Kapur, Reuben; Kaplan, Mark H.; Waisman, Ari; Rad, Roland; Schotta, Gunnar; Huehn, Jochen; Kallies, Axel und Korn, Thomas
(2019):
Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.
In: Cell Reports, Bd. 26, Nr. 7
Brandl, Lydia; Zhang, Yina; Kirstein, Nina; Sendelhofert, Andrea; Boos, Sophie Luise; Jung, Peter; Greten, Florian; Rad, Roland und Menssen, Antje
(2019):
Targeting c-MYC through Interference with NAMPT and SIRT1 and Their Association to Oncogenic Drivers in Murine Serrated Intestinal Tumorigenesis.
In: Neoplasia, Bd. 21, Nr. 10: S. 974-988
Tzelepis, Konstantinos; De Braekeleer, Etienne; Aspris, Demetrios; Barbieri, Isaia; Vijayabaskar, M. S.; Liu, Wen-Hsin; Gozdecka, Malgorzata; Metzakopian, Emmanouil; Toop, Hamish D.; Dudek, Monika; Robson, Samuel C.; Hermida-Prado, Francisco; Yang, Yu Hsuen; Babaei-Jadidi, Roya; Garyfallos, Dimitrios A.; Ponstingl, Hannes; Dias, Joao M. L.; Gallipoli, Paolo; Seiler, Michael; Buonamici, Silvia; Vick, Binje; Bannister, Andrew J.; Rad, Roland; Prinjha, Rab K.; Marioni, John C.; Huntly, Brian; Batson, Jennifer; Morris, Jonathan C.; Pina, Cristina; Bradley, Allan; Jeremias, Irmela; Bates, David O.; Yusa, Kosuke; Kouzarides, Tony und Vassiliou, George S.
(2018):
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.
In: Nature Communications, Bd. 9, 5378
[PDF, 2MB]
Mahajan, Ujjwal Mukund; Langhoff, Eno; Goni, Elisabetta; Costello, Eithne; Greenhalf, William; Halloran, Christopher; Ormanns, Steffen; Kruger, Stephan; Böck, Stefan; Ribback, Silvia; Beyer, Georg; Dombroswki, Frank; Weiss, Frank-Ulrich; Neoptolemos, John P.; Werner, Jens; D'Haese, Jan G.; Bazhin, Alexandr; Peterhansl, Julian; Pichlmeier, Svenja; Büchler, Markus W.; Kleeff, Jörg; Ganeh, Paula; Sendler, Matthias; Palmer, Daniel H.; Kohlmann, Thomas; Rad, Roland; Regel, Ivonne; Lerch, Markus M. und Mayerle, Julia
(2018):
Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma.
In: Gastroenterology, Bd. 155, Nr. 5: S. 1625-1639
Knier, Benjamin; Hiltensperger, Michael; Sie, Christopher; Aly, Lilian; Lepennetier, Gildas; Engleitner, Thomas; Garg, Garima; Muschaweckh, Andreas; Mitsdoerffer, Meike; Koedel, Uwe; Hoechst, Bastian; Knolle, Percy; Gunzer, Matthias; Hemmer, Bernhard; Rad, Roland; Merkler, Doron und Korn, Thomas
(2018):
Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity.
In: Nature Immunology, Bd. 19, Nr. 12: S. 1341-1351
Höckendorf, Ulrike; Yabal, Monica; Herold, Tobias; Munkhbaatar, Enkhtsetseg; Rott, Stephanie; Jilg, Stefanie; Kauschinger, Johanna; Magnani, Giovanni; Reisinger, Florian; Heuser, Michael; Kreipe, Hans; Sotlar, Karl; Engleitner, Thomas; Rad, Roland; Weichert, Wilko; Peschel, Christian; Ruland, Jürgen; Heikenwalder, Mathias; Spiekermann, Karsten; Slotta-Huspenina, Julia; Groß, Olaf und Jost, Philipp J.
(2016):
RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.
In: Cancer Cell, Bd. 30, Nr. 1: S. 75-91
Maresch, Roman; Mueller, Sebastian; Veltkamp, Christian; Öllinger, Rupert; Friedrich, Mathias; Heid, Irina; Steiger, Katja; Weber, Julia; Engleitner, Thomas; Barenboim, Maxim; Klein, Sabine; Louzada, Sandra; Banerjee, Ruby; Strong, Alexander; Stauber, Teresa; Gross, Nina; Geumann, Ulf; Lange, Sebastian; Ringelhan, Marc; Varela, Ignacio; Unger, Kristian; Yang, Fengtang; Schmid, Roland M.; Vassiliou, George S.; Braren, Rickmer; Schneider, Günter; Heikenwalder, Mathias; Bradley, Allan; Saur, Dieter und Rad, Roland
(2016):
Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.
In: Nature Communications, Bd. 7, 10770
[PDF, 2MB]
Bassani-Sternberg, Michal; Bräunlein, Eva; Klar, Richard; Engleitner, Thomas; Sinitcyn, Pavel; Audehm, Stefan; Straub, Melanie; Weber, Julia; Slotta-Huspenina, Julia; Specht, Katja; Martignoni, Marc E.; Werner, Angelika; Hein, Rüdiger; Busch, Dirk H.; Peschel, Christian; Rad, Roland; Cox, Jürgen; Mann, Matthias und Krackhardt, Angela M.
(2016):
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry.
In: Nature Communications, Bd. 7, 13404
[PDF, 1MB]
Voland, Petra; Besig, Sophie; Rad, Roland; Braun, Thomas; Baur, Dorothee M.; Perren, Aurel; Langer, Rupert; Hoefler, Heinz und Prinz, Christian
(2009):
Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival.
In: Neuroendocrinology, Nr. 1: S. 66-78
[PDF, 573kB]