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Ley-Zaporozhan, Julia und Wielpuetz, Mark O. (2021): Bildgebung bei chronisch obstruktiver Lungenerkrankung und Asthma. Es gibt hier nichts zu sehen? In: Pneumologe, Bd. 18, Nr. 5: S. 280-296

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Abstract

Chronic obstructive pulmonary disease (COPD) is one of the most prevalent diseases worldwide and one of the three most common causes of death. Therefore, accurate diagnostics are of great importance. These can differentiate distinct phenotypes that can be potentially addressed by specific treatment. The most widely used method is chest X-ray. It depicts the general effects of the alterations. For a more detailed analysis, however, computed tomography (CT) is indispensable. It enables various phenotypes to be differentiated, the emphysema dominant and airway dominant types. Emphysema in turn can be subdivided into different subcategories, namely centrilobular emphysema, severe destructive and panlobular emphysema. Based on this classification various treatment and other differential diagnostic options arise, e.g. clarification of a possible alpha1 antitrypsin deficiency. In addition, CT images can be quantitatively analyzed, which enables a more precise grading and follow-up. In addition to static CT, dynamic CT can be used, e.g. to detect tracheobronchomalacia and to determine hyperinflated lung regions not participating in gas exchange. This information and knowledge about the integrity of pulmonary fissures is important for planning interventional treatment. In addition to these established imaging techniques further functional methods, especially with magnetic resonance imaging (MRI), can be employed but which are primarily for research purposes. In asthma the main indication for imaging is the diagnostics of surrounding tissues and exclusion of other differential diagnoses such as heart failure or COPD.

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