Logo Logo
Hilfe
Hilfe
Switch Language to English

Remi, Constanze und Gerlach, Christina (2021): „Off label use“ in der Palliativmedizin. In: Onkologe, Bd. 27, Nr. 11: S. 1137-1150

Volltext auf 'Open Access LMU' nicht verfügbar.

Abstract

Palliative care serves to improve the quality of life in patients suffering from incurable diseases. Pharmacotherapy of distressing symptoms plays an important role. Off-label use refers to the use of drugs outside the marketing authorization. In addition to the indications off-label use may also be due to duration of treatment, route of administration and the admixture of substances. Off-label use is common in palliative and hospice care and is probably unavoidable in many cases. For treatment planning and realization of off-label therapy in clinical practice, patient-related aspects, information, therapy monitoring and documentation of therapy effects should be considered in addition to drug-related information. Only in this way it is possible to offer a scientifically adequate, appropriate and economic therapy that is linked to an appropriate risk-benefit ratio for the individual patient. Due to the lack of authorization studies, reporting is of particular importance.

Dokument bearbeiten Dokument bearbeiten