Acute HIV infection syndrome mimicking COVID-19 vaccination side effects: a case report

Triebelhorn, Julian; Haschka, Stefanie; Hesse, Felix; Erber, Johanna; Weidlich, Simon; Lee, Marcel; Hoffmann, Dieter; Eberle, Josef and Spinner, Christoph D. (2021): Acute HIV infection syndrome mimicking COVID-19 vaccination side effects: a case report. In: Aids Research and Therapy, Vol. 18, No. 1, 78

Abstract

Background Symptoms of primary HIV infection, including fever, rash, and headache, are nonspecific and are often described as flu-like. COVID-19 vaccination side effects, such as fever, which occur in up to 10% of people following COVID-19 vaccination, can make the diagnosis of acute HIV infection even more challenging. Case presentation A 26-year-old man presented with fever and headache following COVID-19 vaccination. The symptoms were initially thought to be vaccine side effects. A diagnostic workup was conducted due to persisting fever and headache > 72 h following vaccination, and he was diagnosed with Fiebig stage II acute HIV infection, 3 weeks after having unprotected anal intercourse with another man. Conclusion Thorough anamnesis is key to estimating the individual risk of primary HIV infection, in patients presenting with flu-like symptoms. Early diagnosis and initiation of antiretroviral therapy is associated with better prognosis and limits transmission of the disease.

• Item Type: Journal article
• Faculties: Medicine
• Subjects: 600 Technology > 610 Medicine and health
• ISSN: 1742-6405
• Language: English