Abstract
Patients suffering from neurodegenerative disorders such as Parkinson's or Huntington's disease exhibit speech impairments that affect their communication capabilities. The automatic assessment of the speech of the patients allows to develop computer aided tools to support the diagnosis and to evaluate the disease severity, which helps clinicians to make timely decisions about the treatment of the patients. This paper extends our previous studies about methods to classify patients with neurodegenerative dis-eases from speech. The proposed approach considers convolutional neural networks trained with time frequency representations and a transfer learning strategy to classify different speech impairments in pa-tients that are native of different languages. The transfer learning schemes aim to improve the accuracy of the models when the weights of a neural network are initialized with utterances from a different cor-pus than the one used for the test set. The proposed methodology is evaluated with speech data from Parkinson's disease patients, who are Spanish, German, and Czech native speakers, Huntington's disease patients, who are Czech native speakers, and English native speakers affected by laryngeal impairments. We performed experiments in two scenarios: (1) transfer learning among languages, where a base model is transferred to classify patients with the same disease, but who speak a different language, and (2) transfer learning among diseases, where the base model is transferred to a corpus from patients with a different disease. The results suggest that the transfer learning schemes improve the accuracy in the tar-get corpus only when the base model is accurate enough to transfer the knowledge to the target corpus. This behavior is observed in different scenarios of both transfer learning among languages and diseases. (c) 2021 Elsevier B.V. All rights reserved.
Item Type: | Journal article |
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Faculties: | Medicine |
Subjects: | 600 Technology > 610 Medicine and health |
ISSN: | 0167-8655 |
Language: | English |
Item ID: | 102764 |
Date Deposited: | 05. Jun 2023, 15:41 |
Last Modified: | 17. Oct 2023, 15:12 |