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Zierl, Stephan; Guertler, Anne; Hildebrand, Johannes A.; Clanner-Engelshofen, Benjamin M.; French, Lars E. und Reinholz, Markus (2021): A comprehensive epidemiological study of rosacea in Germany. In: European Journal of Dermatology, Bd. 31, Nr. 6: S. 744-751

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Abstract

Background: Rosacea is one of the most common skin diseases causing great distress in affected patients. For optimal patient care, epidemiological studies on disease distribution and clinical aspects are essential. Objectives: The goal of this study was to provide an updated perspective on the current state of rosacea epidemiology in Germany. Materials & Methods: A cohort of 777 rosacea patients was assessed based on a detailed online questionnaire. Information regarding patients' demographics, course and clinical presentation of rosacea, trigger factors, dermatological consultations, treatment adherence and satisfaction as well as quality of life were obtained. Results: There was a very high self-reported prevalence of primary and secondary rosacea features (flushing: n = 726, 93.4%;papules/pustules: n = 613, 79.0%;telangiectasia: n = 590, 75.9%;subjective symptoms: n = 691, 88.9%). However, these clinical findings were often underdiagnosed by the treating physicians, while changes in temperature and ultraviolet radiation were potent triggers across all patients (86.3%, 77.7%, respectively). Disease-related quality of life decreased with the number of drugs prescribed as well as with uncontrolled symptom activity, and was reduced in female patients. Conclusion: This study is the largest German-based assessment exclusively focusing on rosacea patients covering a variety of clinical aspects to optimize patient care.

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