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Schwach, Jonathan and Stengl, Andreas (2022): Antikörperkonjugate — Präzisionswerkzeuge mit grenzenloser Vielfalt. In: BIOspektrum, Vol. 28, No. 6: pp. 612-614 [PDF, 531kB]

Abstract

Antibody conjugates are a prime example of Aristotle’s famous quote: “The whole is more than the sum of its parts”. Connecting the antibody’s high binding specificity with molecules such as toxins, dyes and nucleic acids opens the doors wide to a world of high precision molecules with high versatility. In this article, we outline the concept of antibody conjugates, describe why the conjugation method matters and introduce two prominent examples that have made their way into the clinic and research labs.

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