Sleep duration in preschool age and later behavioral and cognitive outcomes

Guerlich, Kathrin; Avraam, Demetris; Cadman, Tim; Calas, Lucinda; Charles, Marie-Aline; Elhakeem, Ahmed; Fernandez-Barres, Silvia; Guxens, Monica; Heude, Barbara; Ibarluzea, Jesus; Inskip, Hazel; Julvez, Jordi; Lawlor, Deborah A.; Murcia, Mario; Salika, Theodosia; Sunyer, Jordi; Tafflet, Muriel; Koletzko, Berthold; Grote, Veit und Plancoulaine, Sabine (2024): Sleep duration in preschool age and later behavioral and cognitive outcomes. An individual participant data meta-analysis in five European cohorts. In: European Child & Adolescent Psychiatry, Bd. 33: S. 167-177

Abstract

Short sleep duration has been linked to adverse behavioral and cognitive outcomes in schoolchildren, but few studies examined this relation in preschoolers. We aimed to investigate the association between parent-reported sleep duration at 3.5 years and behavioral and cognitive outcomes at 5 years in European children. We used harmonized data from fve cohorts of the European Union Child Cohort Network: ALSPAC, SWS (UK); EDEN, ELFE (France); INMA (Spain). Associations were estimated through DataSHIELD using adjusted generalized linear regression models ftted separately for each cohort and pooled with random-efects meta-analysis. Behavior was measured with the Strengths and Difculties Questionnaire. Language and non-verbal intelligence were assessed by the Wechsler Preschool and Primary Scale of Intelligence or the McCarthy Scales of Children’s Abilities. Behavioral and cognitive analyses included 11,920 and 2981 children, respectively (34.0%/13.4% of the original sample). In meta-analysis, longer mean sleep duration per day at 3.5 years was associated with lower mean internalizing and externalizing behavior percentile scores at 5 years (adjusted mean diference: − 1.27, 95% CI [− 2.22, − 0.32] / − 2.39, 95% CI [− 3.04, − 1.75]). Sleep duration and language or non-verbal intelligence showed trends of inverse associations, however, with imprecise estimates (adjusted mean diference: − 0.28, 95% CI [− 0.83, 0.27] / − 0.42, 95% CI [− 0.99, 0.15]). This individual participant data meta-analysis suggests that longer sleep duration in preschool age may be important for children’s later behavior and highlight the need for larger samples for robust analyses of cognitive outcomes. Findings could be infuenced by confounding or reverse causality and require replication.

• Dokumententyp: Zeitschriftenartikel
• EU-Projekte: Horizon 2020 > RIA - Research and Innovation action > LIFECYCLE - Early-life stressors and LifeCycle health
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• Bemerkung: Published online 07 February 2023
• Sprache: Englisch