Die Dunkelfeld-Radiografie – ein neuer Weg zur Diagnostik von Gichterkrankungen bei Vögeln und Reptilien?

Roiser, Nathalie; Scholz, Josef; Kimm, Melanie A.; Andrejewski, Jana; Baumgartner, Christine; Braig, Eva; Herzen, Julia; Pfeiffer, Daniela und Korbel, Rüdiger (2022): Die Dunkelfeld-Radiografie – ein neuer Weg zur Diagnostik von Gichterkrankungen bei Vögeln und Reptilien? In: Tierärztliche Praxis / K, Kleintiere, Bd. 50, Nr. 3: S. 185-196

Abstract

Objective The aim of this study is to evaluate whether X-ray dark-field (DF) radiography is useful for the diagnosis of gout in birds and reptiles and whether this preclinical model could be helpful to establish this non-invasive imaging method in human medicine. Material and Methods A total of 18 limbs originating from 11 birds (7 different species) and 7 reptiles (4 different species) with and without suspected joint gout were measured using a grating-based X-ray dark-field setup and conventional X-ray examination, respectively. Each image acquisition generated a dark-field and a conventional absorption x-ray image. The results of the individual scans were compared with the results of a pathological examination and arthrocentesis. Results In 5 of the birds and 4 of the reptiles examined, gout was detected by pathologic examination. In each group, uric acid crystals were found in the joints of 3 animals by means of arthrocentesis. The uric acid crystals were detectable in 2 bird and 2 reptile limbs in the dark-field image. Conclusion The study demonstrated that the urate crystals evoke a clearly visible dark field signal, whereas this was not the case in the conventional radiographs.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Tiermedizin > Zentrum für Klinische Tiermedizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 1434-1239
• Sprache: Deutsch