Intravenöse Lipidinfusion bei Katzen als Therapieoption bei Intoxikationen

Walther, Sarah und Doerfelt, Rene (2022): Intravenöse Lipidinfusion bei Katzen als Therapieoption bei Intoxikationen. In: Kleintierpraxis, Bd. 67, Nr. 7: S. 392-402

Abstract

Poisoned patients are often presented as life-threatening emergencies. Specific antidotes are available for a few specific toxins only. In the last two decades, intravenous infusion of lipid emulsions has been propagated as a treatment option for severe lipophilic intoxications. The proposed mechanism of action is a lipid vehicle function to redistribute the lipophilic toxins from the site of action into systemic circulation. To date, only few case reports pertaining to treatment of cats using intravenous lipid infusion following intoxication with lipophilic toxins, and only one prospective study in cats with permethrin intoxication are published. A variety of suggested dosages can be found in literature. The currently preferred dosage is the intravenous application of 1,5 ml/kg bolus of a 20 % lipid emulsion, followed by a constant rate infusion of 0.25-0.5 ml/kg/min over 30-60 minutes. Due to potential side effects, such as fat overload syndrome, pancreatitis or sepsis following application of contaminated emulsions and a possible increase of toxin resorption from the gastrointestinal tract, patient stabilization and decontamination are mandatory before initiating lipid therapy. This review article describes the use of intravenous lipid therapy, its effects and side effects in cats based on currently published studies and case reports.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Tiermedizin > Zentrum für Klinische Tiermedizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0023-2076
• Sprache: Deutsch