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Klein, Alexander und Dürr, Hans Roland (2022): Biologische Rekonstruktionen: Was ist realistisch machbar? In: Onkologie, Bd. 28, Nr. 7: S. 589-594

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Abstract

Background Surgical resections are an important part in the treatment of bone tumors. For the restoration of function of the affected limb, there are two methods of reconstruction: endoprosthesis implantation or biological reconstruction. The first option allows early restoration of function but is associated with long-term problems, while biological reconstruction offers a permanent solution, especially for young patients but revisions are often required in the early course until bony consolidation. Methods Basically, the following methods are available for biological reconstructions: autologous (patient's own) bone, allogenic bone (donor bone) or alloplastic (industrially produced) materials. Combinations of these materials are also possible. Results and conclusion Several methods of reconstruction have been developed since the 19th century and are established in clinical practice. The use of allogenic bone chips and massive allografts, reconstruction with autologous fibula, replantation of the sterilized resected specimen and segment transfers. All methods have advantages and disadvantages;some methods can be combined. Consultation with an experienced orthopedic tumor surgeon is essential for selection of the optimal procedure.

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