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Otto, Sven und Ristow, Oliver (2022): Antiresorptiva-assoziierte Kiefernekrosen – ein Update. In: Mkg-Chirurg, Vol. 15, No. 1: pp. 59-74

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Abstract

Antiresorptive drug-related osteonecrosis of the jaw still poses major challenges for both patients and practitioners, as therapeutic measures must always be weighed up on a patient-specific basis in the overall context of the underlying diseases. However, in the almost 20 years since the first description of a relationship between the use of antiresorptive drugs and development of osteonecrosis of the jaw, significant progress has been made with regard to the perception, prevention, and treatment of this disease. Although a multifactorial pathogenesis is very likely, there is increasing evidence in the literature that soft tissue and odontogenic infections in the jaw region could play a key role in development of the disease. As a result, preventive measures, early diagnosis, and treatment are becoming increasingly important. Therefore, a good interdisciplinary exchange between all involved disciplines is of particular importance.

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