YeastMate: neural network-assisted segmentation of mating and budding events in Saccharomyces cerevisiae

Bunk, David; Moriasy, Julian; Thoma, Felix; Jakubke, Christopher; Osman, Christof und Hoerl, David (2022): YeastMate: neural network-assisted segmentation of mating and budding events in Saccharomyces cerevisiae. In: Bioinformatics, Bd. 38, Nr. 9: S. 2667-2669

Abstract

Here, we introduce YeastMate, a user-friendly deep learning-based application for automated detection and segmentation of Saccharomyces cerevisiae cells and their mating and budding events in microscopy images. We build upon Mask R-CNN with a custom segmentation head for the subclassification of mother and daughter cells during lifecycle transitions. YeastMate can be used directly as a Python library or through a standalone application with a graphical user interface (GUI) and a Fiji plugin as easy-to-use frontends.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Biologie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften; Biologie
• ISSN: 1367-4803
• Sprache: Englisch