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Postl, Lukas; Mücke, Thomas; Hunger, Stefan; Wuersching, Sabina Noreen; Holberg, Svenia; Bissinger, Oliver; Burgkart, Rainer; Malek, Michael und Krennmair, Stefan (2022): Biopsies of osseous jaw lesions using 3D-printed surgical guides: a clinical study. In: European Journal of Medical Research, Bd. 27, Nr. 1, 104

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Abstract

Background Bone biopsies are often necessary to make a diagnosis in the case of irregular bone structures of the jaw. A 3D-printed surgical guide may be a helpful tool for enhancing the accuracy of the biopsy and for ensuring that the tissue of interest is precisely removed for examination. This study was conducted to compare the accuracy of biopsies performed with 3D-printed surgical guides to that of free-handed biopsies. Methods Computed tomography scans were performed on patients with bony lesions of the lower jaw. Surgical guides were planned via computer-aided design and manufactured by a 3D-printer. Biopsies were performed with the surgical guides. Bone models of the lower jaw with geometries identical to the patients' lower jaws were produced using a 3D-printer. The jaw models were fitted into a phantom head model and free-handed biopsies were taken as controls. The accuracy of the biopsies was evaluated by comparing the parameters for the axis, angle and depth of the biopsies to the planned parameters. Results Eight patients were included. The mean deviation between the biopsy axes was significantly lower in guided procedures than in free-handed biopsies (1.4 mm +/- 0.9 mm;3.6 mm +/- 1.0 mm;p = 0.0005). The mean biopsy angle deviation was also significantly lower in guided biopsies than in free-handed biopsies (6.8 degrees +/- 4.0;15.4 degrees +/- 3.6;p = 0.0005). The biopsy depth showed no significant difference between the guided and the free-handed biopsies. Conclusions Computer-guided biopsies allow significantly higher accuracy than free-handed procedures.

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