Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany

Erber, Johanna; Kappler, Verena; Haller, Bernhard; Mijocevic, Hrvoje; Galhoz, Ana; da Costa, Clarissa Prazeres; Gebhardt, Friedemann; Graf, Natalia; Hoffmann, Dieter; Thaler, Markus; Lorenz, Elke; Roggendorf, Hedwig; Kohlmayer, Florian; Henkel, Andreas; Menden, Michael P.; Ruland, Jürgen; Spinner, Christoph D.; Protzer, Ulrike; Knolle, Percy und Lingor, Paul (2022): Infection Control Measures and Prevalence of SARS-CoV-2 IgG among 4,554 University Hospital Employees, Munich, Germany. In: Emerging Infectious Diseases, Bd. 28, Nr. 3: S. 572-581

Abstract

Hospital staff are at high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during the coronavirus disease (COVID-19) pandemic. This cross-sectional study aimed to determine the prevalence of SARS-CoV-2 infection in hospital staff at the University Hospital rechts der Isar in Munich, Germany, and identify modulating factors. Overall seroprevalence of SARS-CoV-2-IgG in 4,554 participants was 2.4%. Staff engaged in direct patient care, including those working in COVID-19 units, had a similar probability of being seropositive as non-patient-facing staff. Increased probability of infection was observed in staff reporting interactions with SARS-CoV-2-infected coworkers or private contacts or exposure to COVID-19 patients without appropriate personal protective equipment. Analysis of spatiotemporal trajectories identified that distinct hotspots for SARS-CoV-2-positive staff and patients only partially overlap. Patient-facing work in a healthcare facility during the SARS-CoV-2 pandemic might be safe as long as adequate personal protective equipment is used and infection prevention practices are followed inside and outside the hospital

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Biologie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften; Biologie
• ISSN: 1080-6040
• Sprache: Englisch