Cardiac Phenotypes in Secondary Hypertension JACC State-of-the-Art Review

Januszewicz, Andrzej; Mulatero, Paolo; Dobrowolski, Piotr; Monticone, Silvia; Niepen, Patricia van der; Reincke, Martin; Rexhaj, Emrush; Eisenhofer, Graeme; Januszewicz, Magdalena; Kasiakogias, Alexandros; Kreutz, Reinhold; Lenders, Jacques W. M.; Muiesan, Maria Lorenza; Persu, Alexandre; Agabiti-Rosei, Enrico; Soria, Rodrigo; Spiewak, Mateusz; Prejbisz, Aleksander und Messerli, Franz H. (2022): Cardiac Phenotypes in Secondary Hypertension JACC State-of-the-Art Review. In: Journal of the American College of Cardiology, Bd. 80, Nr. 15: S. 1480-1497

Abstract

Several forms of secondary hypertension carry a high risk of cardiac morbidity and mortality. Evaluation of cardiac phenotypes in secondary hypertension provides a unique opportunity to study underlying hormonal and biochemical mechanisms affecting the heart. We review the characteristics of cardiac dysfunction in different forms of secondary hypertension and clarify the mechanisms behind the higher prevalence of heart damage in these patients than in those with primary hypertension. Attention to the specific clinical/biochemical phenotypes of these conditions may assist clinicians to screen for and confirm secondary forms of hypertension. Thereby, early signs of heart damage can be recognized and monitored, allowing individualized treatment to delay or prevent evolution toward more advanced disease. (C) 2022 by the American College of Cardiology Foundation.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 0735-1097
• Sprache: Englisch
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 314061271