ORCID: https://orcid.org/0000-0002-8817-8457
(2023):
Association of the time of day of EVT with clinical outcomes and benefit from successful recanalization after stroke.
In: Annals of Clinical and Translational Neurology, Vol. 10, No. 10: pp. 1917-1923
[PDF, 768kB]
Abstract
Experimental and neuroimaging studies suggest an influence of the time of day on acute infarct growth, but whether this could inform patient selection for acute treatments is uncertain. In a multicenter cohort of 9357 stroke patients undergoing endovascular treatment, morning treatment (05:00–10:59) was associated with lowest 90-day mRS scores (adjusted odds ratio, 1.27 [95% CI, 1.08–1.47]; p = 0.004). The association between successful recanalization and outcome was stronger in morning compared to evening-treated patients (pia = 0.046) with treatment benefit persisting until 24 h for morning-treated compared to 11.5 h for evening-treated patients suggesting that the time of day might inform patient selection for EVT.
Item Type: | Journal article |
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Faculties: | Medicine > Institute for Stroke and Dementia Research (ISD) |
Subjects: | 600 Technology > 610 Medicine and health |
URN: | urn:nbn:de:bvb:19-epub-116302-6 |
ISSN: | 2328-9503 |
Language: | English |
Item ID: | 116302 |
Date Deposited: | 08. May 2024, 08:55 |
Last Modified: | 08. May 2024, 08:55 |
DFG: | Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 491502892 |