Logo Logo
Switch Language to German

Burbano, Vanessa Granja; Wölfer, Teresa A.; Vlegels, Naomi; Quandt, Fanny; Zimmermann, Hanna; Wischmann, Johannes; Kellert, Lars; Liebig, Thomas; Dimitriadis, Konstantinos; Saver, Jeffrey L. and Tiedt, Steffen ORCID logoORCID: https://orcid.org/0000-0002-8817-8457 (2023): Association of the time of day of EVT with clinical outcomes and benefit from successful recanalization after stroke. In: Annals of Clinical and Translational Neurology, Vol. 10, No. 10: pp. 1917-1923 [PDF, 768kB]


Experimental and neuroimaging studies suggest an influence of the time of day on acute infarct growth, but whether this could inform patient selection for acute treatments is uncertain. In a multicenter cohort of 9357 stroke patients undergoing endovascular treatment, morning treatment (05:00–10:59) was associated with lowest 90-day mRS scores (adjusted odds ratio, 1.27 [95% CI, 1.08–1.47]; p = 0.004). The association between successful recanalization and outcome was stronger in morning compared to evening-treated patients (pia = 0.046) with treatment benefit persisting until 24 h for morning-treated compared to 11.5 h for evening-treated patients suggesting that the time of day might inform patient selection for EVT.

Actions (login required)

View Item View Item