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Haum, Magda ORCID logoORCID: https://orcid.org/0000-0001-5241-4692; Steffen, Julius ORCID logoORCID: https://orcid.org/0000-0002-8807-7365; Sadoni, Sebastian; Theiss, Hans; Stark, Konstantin ORCID logoORCID: https://orcid.org/0000-0002-5369-8399; Estner, Heidi; Massberg, Steffen ORCID logoORCID: https://orcid.org/0000-0001-7387-3986; Deseive, Simon ORCID logoORCID: https://orcid.org/0000-0001-8768-1184 und Lackermair, Korbinian ORCID logoORCID: https://orcid.org/0000-0002-6009-960X (2024): Pacing Using Cardiac Implantable Electric Device During TAVR. In: JACC Cardiovascular Interventions, Bd. 17, Nr. 8: S. 1020-1028 [PDF, 808kB]

Abstract

Background: Transcatheter aortic valve replacement (TAVR) is an effective and safe therapy for severe aortic stenosis. Rapid or fast pacing is required for implantation, which can be performed via a pre-existing cardiac implantable electric device (CIED). However, safety data on CIEDs for pacing in TAVR are missing. Objectives: The aim of this study was to elucidate procedural safety and feasibility of internal pacing with a CIED in TAVR. Methods: Patients undergoing TAVR with a CIED were included in this analysis. Baseline characteristics, procedural details, and complications according to Valve Academic Research Consortium 3 (VARC-3) criteria after TAVR were compared between both groups. Results: A total of 486 patients were included. Pacing was performed using a CIED in 150 patients and a transient pacemaker in 336 patients. No differences in technical success according to VARC-3 criteria or procedure duration occurred between the groups. The usage of transient pacers for pacing was associated with a significantly higher bleeding rate (bleeding type ≥2 according to VARC-3-criteria; 2.0% vs 13.1%; P < 0.01). Furthermore, impairment of the CIED appeared in 2.3% of patients after TAVR only in the group in which pacing was performed by a transient pacer, leading to surgical revision of the CIED in 1.3% of all patients when transient pacemakers were used. Conclusions: Internal pacing using a CIED is safe and feasible without differences of procedural time and technical success and might reduce bleeding rates. Furthermore, pacing using a CIED circumvents the risk of lead dislocation. Our data provide an urgent call for the use of a CIED for pacing during a TAVR procedure in general.

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