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Nicolai, Leo ORCID logoORCID: https://orcid.org/0000-0003-0776-5885 und Massberg, Steffen ORCID logoORCID: https://orcid.org/0000-0001-7387-3986 (2024): Myeloid cells take ischemic insult to heart. In: Trends in Immunology, Bd. 45, Nr. 10: S. 735-737

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Abstract

Morbidity and mortality associated with stroke cannot be attributed solely to the acute ischemic event, but are also rooted in long-term complications, including heart disease. Simats, Zhang, and colleagues now demonstrate that interleukin (IL)-1ß-mediated innate immune memory after brain ischemic stroke leads to proinflammatory changes in the heart causing myocardial fibrosis.

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