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Kawula, Maria ORCID logoORCID: https://orcid.org/0000-0002-5039-8278; Marschner, Sebastian ORCID logoORCID: https://orcid.org/0000-0002-8121-358X; Wei, Chengtao; Ribeiro, Marvin F.; Corradini, Stefanie ORCID logoORCID: https://orcid.org/0000-0001-8709-7252; Belka, Claus ORCID logoORCID: https://orcid.org/0000-0002-1287-7825; Landry, Guillaume ORCID logoORCID: https://orcid.org/0000-0003-1707-4068 und Kurz, Christopher (2025): Personalized deep learning auto‐segmentation models for adaptive fractionated magnetic resonance‐guided radiation therapy of the abdomen. In: Medical Physics, Bd. 52, Nr. 4: S. 2295-2304 [PDF, 1MB]

Abstract

Background: Manual contour corrections during fractionated magnetic resonance (MR)-guided radiotherapy (MRgRT) are time-consuming. Conventional population models for deep learning auto-segmentation might be suboptimal for MRgRT at MR-Linacs since they do not incorporate manual segmentation from treatment planning and previous fractions.

Purpose: In this work, we investigate patient-specific (PS) auto-segmentation methods leveraging expert-segmented planning and prior fraction MR images (MRIs) to improve auto-segmentation on consecutive treatment days.

Conclusion: Personalized auto-segmentation models outperformed the population BMs. In most cases, PS(BM) delineations were judged to be directly usable for treatment adaptation without further corrections, suggesting a potential time saving during fractionated treatment.

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