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Hubert, Jasmin; Schmidt, Vivien ORCID logoORCID: https://orcid.org/0009-0003-3006-3926; Wittmann, Esther ORCID logoORCID: https://orcid.org/0000-0003-2752-988X; Melder, Anja ORCID logoORCID: https://orcid.org/0000-0002-9214-7776; Lomidze, Anna; Smit, Nancy; Bulubas, Lucia ORCID logoORCID: https://orcid.org/0000-0002-5797-8742; Campana, Mattia ORCID logoORCID: https://orcid.org/0000-0003-4596-4287; Vogelmann, Ulrike ORCID logoORCID: https://orcid.org/0000-0001-5005-0709; Dornheim, Beate; Padberg, Frank ORCID logoORCID: https://orcid.org/0000-0001-7638-8310; Heinen, Florian ORCID logoORCID: https://orcid.org/0000-0002-3872-6136 und Landgraf, Mirjam N. ORCID logoORCID: https://orcid.org/0000-0002-6581-721X (2025): Transcranial magnetic stimulation in children with fetal alcohol spectrum disorder: A randomised, crossover pilot-trial. In: European Journal of Paediatric Neurology, Bd. 55: S. 111-120 [PDF, 4MB]

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Abstract

Highlights •First study of high-frequency rTMS (10Hz, iTBS) with real 1Hz-rTMS as control in children with FASD.

•Protocols were safe and well tolerated with only mild, self-limiting adverse events.

•10Hz–rTMS and iTBS led to improved task-performance in attention and self-assessment of social-emotional regulation.

•There were no TMS-effects on executive functions or quality of life.

•The preliminary evidence of positive TMS-effects calls for further investigation in larger, placebo-controlled trials.

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