Clinical application and new visualization techniques of 3D-quantitative motion analysis in epileptic seizures characterized by ictal automatic movements

Loesch-Biffar, Anna Mira; Karácsony, Tamás; Sattlegger, Leah; Vollmar, Christian ; Rémi, Jan ; Silva Cunha, João Paulo und Noachtar, Soheyl (2025): Clinical application and new visualization techniques of 3D-quantitative motion analysis in epileptic seizures characterized by ictal automatic movements. In: Epilepsy & Behavior, Bd. 170, 110486

Abstract

Purpose

Our aim was to test the capability of the NeuroKinect 3D-method, as a movement visualization technique and quantitative analysis to differentiate ictal movements such as hyperkinetic and focal seizures with manual automatisms. The dataset is extracted from the NeuroKinect dataset, which is a RGB-D-IR dataset of epileptic seizures. The dataset is recorded with Kinect v2 and consists of RGB, Infrared (IR) and depth streams.

Quantitative 3D-movement analysis of 20 motor seizures was performed. Velocity, acceleration, jerk, covered distance, displacement and movement extent of Regions of Interests (= ROI: head, right hand, left hand and trunk) were captured.

Results

Among the analyzed seizures were 10 hyperkinetic (n = 7: 4 male, 3 female; mean age 39.6 years (SD ± 9.7)) and 10 focal seizures with manual automatisms (n = 10: 2 male, 8 female; mean age 39.2 years (SD ± 17.6)). Hyperkinetic seizures exhibited higher mean velocity in all ROIs (e.g. head = 0.62 ± 0.28 (m/s) vs. 0.12 ± 0.07 (m/s)) as well as higher mean acceleration and mean jerk in most ROIs; these differences were statistically significant. Mean movement extent, covered distance, and displacement for all ROIs were larger for hyperkinetic seizures, however not significantly. The duration of ictal movements (80 s ± 38 s versus 26 s ± 14 s; p = 0.001) was significantly longer in focal seizures with manual automatisms.

Conclusions

This new visualization technique allows to reconstruct tracked movement via 3D viewer and supports a 3D movement quantification which is capable to differentiate seizures characterized by movements, which may help to localize the epileptogenic zone.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin > Klinikum der LMU München > Neurologische Klinik und Poliklinik mit Friedrich-Baur-Institut
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 15255050
• Sprache: Englisch