Abstract
Olson and Wijsman (1993) have proposed a robust linkage analysis between quantitative traits and a marker locus using all relative pairs. We extend their work to estimate the recombination fraction using minimum distance estimation after robust linkage analysis requiring a single marker locus. The relevant parameters of the genetic model can also be estimated in the presence of linkage. We illustrate our approach by simulations.
| Item Type: | Paper |
|---|---|
| Faculties: | Mathematics, Computer Science and Statistics > Statistics > Collaborative Research Center 386 Special Research Fields > Special Research Field 386 |
| Subjects: | 500 Science > 510 Mathematics |
| Language: | English |
| Item ID: | 1459 |
| Date Deposited: | 04. Apr 2007 |
| Last Modified: | 11. May 2017, 14:07 |
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