ORCID: https://orcid.org/0000-0002-4859-8000 and Hemmen, Jan Leo van
(26. April 2005):
Spiking Neurons Learning Phase Delays. How Mammals May Develop Auditory Time-Difference Sensitivity.
In: Physical Review Letters, Vol. 94, No. 16: p. 168102
[PDF, 170kB]

Abstract
Time differences between the two ears are an important cue for animals to azimuthally locate a sound source. The first binaural brainstem nucleus, in mammals the medial superior olive, is generally believed to perform the necessary computations. Its cells are sensitive to variations of interaural time differences of about 10 μs. The classical explanation of such a neuronal time-difference tuning is based on the physical concept of delay lines. Recent data, however, are inconsistent with a temporal delay and rather favor a phase delay. By means of a biophysical model we show how spike-timing-dependent synaptic learning explains precise interplay of excitation and inhibition and, hence, accounts for a physical realization of a phase delay.
Item Type: | Journal article |
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Form of publication: | Publisher's Version |
Faculties: | Biology > Department Biology II > Neurobiology |
Subjects: | 500 Science > 570 Life sciences; biology |
URN: | urn:nbn:de:bvb:19-epub-14755-7 |
ISSN: | 1079-7114 |
Annotation: | © 2005 The American Physical Society |
Language: | English |
Item ID: | 14755 |
Date Deposited: | 12. Mar 2013, 12:13 |
Last Modified: | 04. Nov 2020, 12:55 |